Results 51 to 60 of about 34,995 (285)

Fluorescent microplate-based analysis of protein-DNA interactions II: immobilized DNA

open access: yesBioTechniques, 2003
A simple protein-DNA interaction analysis has been developed using both a high-affinity/high-specificity zinc finger protein and a low-specificity zinc finger protein with nonspecific DNA binding capability.
Zhan-Ren Zhang   +4 more
doaj   +1 more source

Base eversion and shuffling by DNA methyltransferases

open access: yesChemistry & Biology, 1996
The structures of two DNA cytosine methyltransferases reveal two novel methods of gaining access to the substrate cytosine residue, both of which involve eversion of the cytosine in a process that may require DNA bending. In one instance there is also widespread base shuffling and distortion of the DNA.
Nelsons, Hillary C.M.   +1 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Breaking an Image Encryption Algorithm Based on DNA Encoding and Spatiotemporal Chaos

open access: yesEntropy, 2019
Recently, an image encryption algorithm based on DNA encoding and spatiotemporal chaos (IEA-DESC) was proposed. In IEA-DESC, pixel diffusion, DNA encoding, DNA-base permutation and DNA decoding are performed successively to generate cipher-images from ...
Heping Wen, Simin Yu, Jinhu Lü
doaj   +1 more source

Barlow-Hall in vitro Evolution Protocol [PDF]

open access: yes, 2008
The Barlow-Hall method for in vitro evolution is a simple alternative to methods such as DNA shuffling and is particularly applicable to predicting the evolution of target genes in nature.
Barry G. Hall, Miriam Barlow
core   +1 more source

Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes

open access: yes, 2008
By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin   +20 more
core   +1 more source

Memory beyond memory in heart beating: an efficient way to detect pathological conditions [PDF]

open access: yes, 2001
We study the long-range correlations of heartbeat fluctuations with the method of diffusion entropy. We show that this method of analysis yields a scaling parameter $\delta$ that apparently conflicts with the direct evaluation of the distribution of ...
A. L. Goldberger   +14 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Enhanced production of tanshinone IIA in endophytic fungi Emericella foeniculicola by genome shuffling

open access: yesPharmaceutical Biology, 2018
Context: Tanshinone IIA, commercially produced from Salvia miltiorrhiza Bunge (C.Y.Wu) (Labiatae), has various biological benefits. Currently, this compound is mainly extracted from plants.
Pengyu Zhang   +5 more
doaj   +1 more source

Complexity-entropy analysis at different levels of organization in written language

open access: yes, 2019
Written language is complex. A written text can be considered an attempt to convey a meaningful message which ends up being constrained by language rules, context dependence and highly redundant in its use of resources.
Estevez-Moya, D.   +2 more
core   +2 more sources

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