Results 41 to 50 of about 3,653,794 (230)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Linking denitrifiers with sulfamethoxazole biodegradation: insights from DNA-based stable isotope probing

Biocontaminant
Antibiotics are widespread in estuarine and coastal ecosystems, posing ecological risks to organisms and microbially mediated nitrogen cycling. This study, for the first time, employed 15N tracing and DNA-stable-isotope probing (DNA-SIP) techniques to ...
Chuangchuang Li, Xiufeng Tang, Guoyu Yin, Ping Han, Cheng Chen, Jiongyu Pan, Zhiyu Zhou, Ye Li, Lijun Hou, Min Liu   +9 more
doaj   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

DNA and RNA Stable Isotope Probing of Methylotrophic Methanogenic Archaea.

, 2019
Methylotrophic methanogenic archaea are an integral part of the carbon cycle in various anaerobic environments. Different from methylotrophic bacteria, methylotrophic methanogens assimilate both, the methyl compound and dissolved inorganic carbon.
Yin, X., Kulkarni, A., Michael W. Friedrich, Xiuran Yin, Friedrich, M., Ajinkya C. Kulkarni   +5 more
core   +1 more source

Targeted metagenomics of active microbial populations with stable-isotope probing [PDF]

, 2016
The ability to explore microbial diversity and function has been enhanced by novel experimental and computational tools. The incorporation of stable isotopes into microbial biomass enables the recovery of labeled nucleic acids from active microorganisms,
Josh D Neufeld, Jennifer Pratscher, Coyotzi, Sara, Murrell, J. Colin, Neufeld, Josh D., Pratscher, Jennifer, J Colin Murrell, Sara Coyotzi   +7 more
core   +1 more source

Stable Isotope Probing-RNA Strategy to Study Plant/Fungus Interactions

, 2023
The use of stable-isotope probing (SIP) allows tracing specific labeled substrates into fungi leading to a better understanding of their role in biogeochemical cycles and their relationship with their environment.
Vandenkoornhuyse, Philippe, Duhamel, Marie, Lê Van, Amandine, Quaiser, Achim   +3 more
core   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Stable Isotope Probing: Methods in Molecular Biology

, 2019
This book provides definitive methods to perform stable isotope probing (SIP) experiments, covering a wide spectrum of stable isotope techniques used in microbial ecology, such as methods to target and analyze labeled DNA, rRNA, mRNA, protein, and PLFA ...
Dumont, Marc, Hernández, Marcela
core   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Quantitative microbial ecology through stable isotope probing

, 2015
Bacteria grow and transform elements at different rates, yet quantifying this variation in the environment is difficult. Determining isotope enrichment with fine taxonomic resolution after exposure to isotope tracers could help, but there are few ...
J Gregory Caporaso, Ember M Morrissey, Cindy M Liu, Paul Dijkstra, Egbert Schwartz, Bruce A Hungate, Jane C Marks, Natasja van Gestel, Rebecca L Mau, Theresa A McHugh, Benjamin J Koch, Lance B Price   +11 more
core   +1 more source