Results 161 to 170 of about 115,106 (246)

The SWIB domain-containing DNA topoisomerase I of <i>Chlamydia trachomatis</i> mediates DNA relaxation. [PDF]

J Bacteriol
Shen L, Swoboda AR, Diggs C, Ferdous S, Terrebonne A, Santos A, Wolf N, Lorenzo Carvajal L, Zhong G, Ouellette SP, Tse-Dinh Y-C.   +10 more
europepmc   +1 more source

Phenotypic Discovery of Thiocarbohydrazone with Anticancer Properties and Catalytic Inhibition of Human DNA Topoisomerase IIα. [PDF]

Pharmaceuticals (Basel), 2023
Cvijetić IN, Herlah B, Marinković A, Perdih A, Bjelogrlić SK.   +4 more
europepmc   +1 more source

Molecular and cellular effects of the combined treatment with Camptothecin and Roscovitine in human lung and colon adenocarcinoma cells [PDF]

, 2008
De Mattia, Roberta
core   +1 more source

Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025.
Kedi Wang, Dongjiang Xu, Yan Gao, Wen Zhao, Kaihui Ma   +4 more
wiley   +1 more source

Targeting DNA Topoisomerase IIα in Retinoblastoma: Implications in EMT and Therapeutic Strategies. [PDF]

Biologics
Wei Q, Lin N, Wang L.
europepmc   +1 more source

Retracted: DNA Topoisomerase II-α Regulated by miR-22-5p Promotes Hepatocellular Carcinoma Invasion and Migration through the Hippo Pathway. [PDF]

Oxid Med Cell Longev, 2023
Longevity OMAC.
europepmc   +1 more source

Leveraging Knowledge of Traditional Italian Maize Landrace Diversity to Identify Signals of Local Adaptation

Evolutionary Applications, Volume 19, Issue 2, February 2026.
ABSTRACT Climate change is the greatest challenge to modern agriculture. It significantly impacts agricultural systems through an increased frequency and intensity of extreme environmental events. Maize, a vital crop for global food security, is particularly vulnerable to these changes, highlighting the urgent need to develop resilient varieties.
Alessandra Lezzi, Lorenzo Stagnati, Leonardo Caproni, Matteo Dell'Acqua, Matteo Busconi, Alessandra Lanubile, Adriano Marocco   +6 more
wiley   +1 more source

The DNA Topoisomerase 1 Contributes to Stress Response in <i>Saccharomyces cerevisiae</i>, Regardless Its Catalytic Activity. [PDF]

Biology (Basel)
D'Alfonso A, Egidi A, Proietti L, Camilloni G.   +3 more
europepmc   +1 more source

Autoantibodies against DNA topoisomerase I promote renal allograft rejection by increasing alloreactive T cell responses. [PDF]

Am J Transplant, 2023
Gorbacheva V, Fan R, Miyairi S, Fairchild RL, Baldwin WM, Valujskikh A.   +5 more
europepmc   +1 more source

Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor. [PDF]

Cell Rep Med
Wang R, Fang P, Chen X, Ji J, Yu D, Mei F, Wang Z, Zhou W, Peng W, Wang R, Wang J, Guo C, Wu H, Liu D, Tan X, Gui X.   +15 more
europepmc   +1 more source