Results 121 to 130 of about 12,251 (152)
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DNA topoisomerases as targets for chemotherapy
The FASEB Journal, 1988DNA topoisomerases are ubiquitous enzymes that alter the configuration or topology of DNA. These enzymes play an important role in replicational, recombinational, and transcriptional events and are a key to cell growth processes.
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DNA topoisomerase: the mechanism of resistance to DNA topoisomerase II inhibitor VP-16. [PDF]
Hiroshima journal of medical sciences, 1990 K6-1 and 50B-3 cell lines, resistant to VP-16, a DNA topoisomerase II inhibitor, were established from two different types of cells respectively: human T-cell derived acute lymphoblastic leukemia cell line RPMI8402 and mouse mammary tumor cell line FM3A.
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Emerging roles of DNA topoisomerases in the regulation of R-loops
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2022Razqallah Hakem +2 more
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Cellular roles of DNA topoisomerases: a molecular perspective
Nature Reviews Molecular Cell Biology, 2002James C Wang
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Eukaryotic DNA topoisomerases I
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1995M, Gupta, A, Fujimori, Y, Pommier
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Antitumor Inhibitors of DNA Topoisomerases
Current Pharmaceutical Design, 1995Giovanni Capranico, F Zunino
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