Results 171 to 180 of about 1,265,065 (269)
Journal of Raman Spectroscopy, Volume 57, Issue 9, Page 1554-1564, September 2026.Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira +3 more
wiley +1 more source
MedComm, Volume 7, Issue 9, September 2026.This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng +9 more
wiley +1 more source
MedComm, Volume 7, Issue 9, September 2026.We report a proof‐of‐concept combination of topoisomerase inhibition and FLASH radiotherapy showing enhanced antitumor activity in head and neck carcinoma biomodels, supporting further investigation of this strategy in more clinically representative models and treatment settings. ABSTRACT Locally advanced head and neck carcinoma remains associated with
Patrizia Sarogni +17 more
wiley +1 more source
MedComm – Oncology, Volume 5, Issue 3, September 2026.The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley +1 more source
DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation. [PDF]
PLoS One, 2015 Roedgaard M +4 more
europepmc +1 more source
New Zealand Journal of Botany, Volume 64, Issue 3, September 2026.Introduction: Cardiotoxicity is an undesirable side effect of chemotherapy that limits the effectiveness of cancer treatment. Almost all cardiotoxic agents cause cardiovascular complications, leading to oxidative stress and other pathological conditions.
Susanna Badalyan +2 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Three benzimidazolium derivatives bearing fluoro, chloro, and methoxy substituents are synthesized and evaluated for anticancer activity. Compound 2b shows the highest antiproliferative activity and induces apoptosis through caspase‐3 activation and PARP1 cleavage. In this study, three novel benzimidazolium derivatives (2a–c) bearing 4‐fluoro, 3‐chloro,
Gulay Dilek, Senem Akkoc
wiley +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Eight chalcone‐sulfonamide hybrids (12a–h) are synthesized via Claisen–Schmidt condensation and evaluated for antibacterial, antioxidant, and anti‐inflammatory activity. The compounds show potent radical scavenging, strong protein‐denaturation inhibition surpassing diclofenac, and favorable docking against DHPS, myeloperoxidase, COX‐2, and ...
Mlis Belete +5 more
wiley +1 more source
The Plant Genome, Volume 19, Issue 3, September 2026.Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang +6 more
wiley +1 more source