Results 131 to 140 of about 60,956 (264)

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez   +4 more
wiley   +1 more source

The repetitive genome of the Ixodes ricinus tick reveals transposable elements have driven genome evolution in ticks. [PDF]

open access: yesGenome Biol
Ronai I   +9 more
europepmc   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng   +11 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

Chromosome-scale genome assembly for yellow wood sorrel, Oxalis stricta. [PDF]

open access: yesG3 (Bethesda)
Wood JC   +5 more
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Identification and Characterisation of five novel Miniature Inverted-repeat Transposable Elements (MITEs) in amphioxus (Branchiostoma floridae)

open access: yesInternational Journal of Biological Sciences, 2006
As the sister group to vertebrates, amphioxus is consistently used as a model of genome evolution for understanding the invertebrate/vertebrate transition.
doaj  

Temperature and genetic background drive mobilization of diverse transposable elements in a global human fungal pathogen. [PDF]

open access: yesPLoS Genet
Mackey AI   +8 more
europepmc   +1 more source

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