Results 131 to 140 of about 256,848 (381)
BMC GenomicsTransposable elements (TEs) are DNA sequences that can move or replicate within a genome, and their study has become increasingly important in understanding genome evolution and function.
Hashim Khan +4 more
doaj +1 more source
Automatic curation of LTR retrotransposon libraries from plant genomes through machine learning
Journal of Integrative Bioinformatics, 2022 Transposable elements are mobile sequences that can move and insert themselves into chromosomes, activating under internal or external stimuli, giving the organism the ability to adapt to the environment.
Orozco-Arias Simon +6 more
doaj +1 more source
Loops are Geometric Catalysts for DNA Integration [PDF]
arXiv, 2023 The insertion of HIV and other DNA elements within genomes underpins both genetic diversity and disease when unregulated. Most of these insertions are not random and occupy specific positions within the genome but the physical mechanisms underlying the integration site selection are poorly understood.
arxiv
Advanced Science, EarlyView.The study identifies a positive feed‐forward loop that intertwines DNA methylation regulator UHRF1 with Homeobox genes‐NKX2‐5/LHX1 via UMRs as a critical driver of ESCC. Pharmacological inhibition of UHRF1 and DNMT activity inhibits ESCC growth, which may represent a promising therapeutic approach to treat ESCC patients dependent on NKX2‐5/LHX1/UHRF1 ...
Xukun Li +13 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 1998 Examination of the reported nucleotide sequences containing avirulence genes of Pseudomonas syringae pathovars suggested that avrA, avrB, avrC, avrPphC, avrRpm1, and avrPpiA1 are bordered by sequences similar to those of transposable elements of gram ...
Jihyun F. Kim +4 more
doaj +1 more source
Identification and characterization of unique to human regulatory sequences in embryonic stem cells reveal associations with transposable elements, distal enhancers, non-coding RNA, and DNA methylation-driven mechanisms of genome editing [PDF]
arXiv, 2014 Despite significant progress in structural and functional characterization of human genome, understanding of mechanisms underlying the genetic basis of human phenotypic uniqueness remains limited. We report that non-randomly distributed transposable element-derived sequences, most notably HERV-H/LTR7 and L1HS, are associated with creation of 99.8 ...
arxiv
DNA transposons have colonized the genome of the giant virus Pandoravirus salinus [PDF]
, 2015 BACKGROUND: Transposable elements are mobile DNA sequences that are widely distributed in prokaryotic and eukaryotic genomes, where they represent a major force in genome evolution.
Cheng Sun +3 more
core +1 more source
Structural and sequence diversity of eukaryotic transposable elements.
Genes & Genetic Systems, 2019 The majority of eukaryotic genomes contain a large fraction of repetitive sequences that primarily originate from transpositional bursts of transposable elements (TEs).
K. Kojima
semanticscholar +1 more source
Advanced Science, EarlyView.In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao +19 more
wiley +1 more source
RNA polymerase V-dependent small RNAs in Arabidopsis originate from small, intergenic loci including most SINE repeats. [PDF]
, 2012 In plants, heterochromatin is maintained by a small RNA-based gene silencing mechanism known as RNA-directed DNA methylation (RdDM). RdDM requires the non-redundant functions of two plant-specific DNA-dependent RNA polymerases (RNAP), RNAP IV and RNAP V.
Chen, Xuemei +7 more
core +2 more sources