Results 151 to 160 of about 62,579 (262)

Manual validation finds ultra-long-read sequencing best enables faithful, population-level structural variant calling in Drosophila melanogaster euchromatin with nanopore. [PDF]

G3 (Bethesda)
Hemker JA, Gellert HR, Smiley-Rhodes JA, Kim BY, Petrov DA.   +4 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Hybrid genome assembly of the cannabis powdery mildew agent Golovinomyces ambrosiae uncovers important resources for deciphering virulence factors. [PDF]

BMC Genomics
Roy FA, Asselin Y, Labbé C, Nguyen GQH, Mohammadi S, Gauthier J, Cinget B, Torkamaneh D, Levesque RC, Bélanger RR.   +9 more
europepmc   +1 more source

Host‐specific and deterministic microbiome assembly in major coleopteran stored‐grain pests

iMetaOmics, EarlyView.
Dual DNA‐ and RNA‐based sequencing profiled the microbiomes of five major coleopteran stored‐grain pests and their wheat flour substrate. The microbiomes differed significantly among hosts and from flour, yet 11 core bacterial and 9 core fungal taxa were shared across hosts. RNA data revealed host‐specific active microbiota.
Abrar Muhammad, Xiaoqiang Shen, Lichao Chen, Enhui Guo, Huarui Zhang, Xiaoyu Lei, Chao Sun, Jianhua Lv, Yongqi Shao   +8 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

Host-Parasite Interactions Revisited: Evidence of Horizontal Transfer of a Transposable Element Between a Snail and Its Parasite. [PDF]

Genome Biol Evol
Brann T, Souza de Oliveira F, Iriarte A, Protasio AV.   +3 more
europepmc   +1 more source

Mammary Tumor Virus DNA: A Glucocorticoid-responsive Transposable Element

Cold Spring Harbor Symposia on Quantitative Biology, 1978
K R, Yamamoto, M R, Stallcup, J, Ring, G M, Ringold   +3 more
openaire   +2 more sources

Warm‐wet transition restructures arid lake microbiomes and functional potential

iMetaOmics, EarlyView.
This study summarizes how a long‐term warm‐dry to warm‐wet transition restructures microbiomes and functional potential in Lake Bosten, an arid lake in northwestern China. Warm‐wet hydroclimatic change increased water level and hydrological connectivity, while decreasing salinity and total nitrogen.
Zhen Shen, Xingchen Li, Zhijun Gong, Yang Hu, Yongjiu Cai, Keqiang Shao, Guang Gao, Robbie M. Martin, Xiangming Tang   +8 more
wiley   +1 more source

Longitudinal Repeatome Remodeling in Peripheral Blood Following Parkinson's Disease Diagnosis. [PDF]

Genes (Basel)
Kulski JK, Koks S.
europepmc   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

iMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei, Tengxiang Lian, Liying Chen, Lanxiang Wang, Junjie Ye, Xiaofang Yao, Shilong Duan, Ziyu Lu, Jinji Tu, Hongfu Li, Xin‐Yue Xu, Jie Zhou, Junliang He, Feiying Zhu, Paola Bonfante, Lam‐Son Phan Tran, Zhiqiang Pang, Xin Zhou, Zhihui Xu, Lin Zhang, Mengcen Wang, Xiaolin Wang, Chang‐Fu Tian, Yong‐Xin Liu, Kai Sun, Ertao Wang, Xianan Xie   +26 more
wiley   +1 more source