Results 1 to 10 of about 26,277 (245)

Comparison of EM-seq and PBAT methylome library methods for low-input DNA

open access: yesEpigenetics, 2022
DNA methylation is the most studied epigenetic mark involved in regulation of gene expression. For low input samples, a limited number of methods for quantifying DNA methylation genome-wide has been evaluated.
Yanara Marincevic-Zuniga, Amanda Raine
exaly   +2 more sources

Methylome-wide analysis in systemic microbial-induced experimental periodontal disease in mice with different susceptibility

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectiveThe study delved into the epigenetic factors associated with periodontal disease in two lineages of mice, namely C57bl/6 and Balb/c. Its primary objective was to elucidate alterations in the methylome of mice with distinct genetic backgrounds ...
Ricardo D Coletta   +2 more
exaly   +3 more sources

Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion

open access: yesEpigenetics, 2017
Exposure to particulate matter (PM) is recognized as a major health hazard, but molecular responses are still insufficiently described. We analyzed the epigenetic impact of ambient PM2.5 from biomass combustion on the methylome of primary human bronchial
Gwang-Jin Kim   +2 more
exaly   +2 more sources

Grass Meal Acts as a Probiotic in Chicken

open access: yesMicrobiology Research, 2023
Probiotics can act as an alternative to antibiotics in animal feeding, but their use is minimal due to their expensive production. Dry grass is rich with bacteria beneficial for animal feeding and can be used as a probiotic.
Elena S. Bogdanova   +7 more
doaj   +1 more source

Complete genome assembly and methylome dissection of Methanococcus aeolicus PL15/Hp

open access: yesFrontiers in Microbiology, 2023
Although restriction-modification systems are found in both Eubacterial and Archaeal kingdoms, comparatively less is known about patterns of DNA methylation and genome defense systems in archaea.
Alexey Fomenkov   +4 more
doaj   +1 more source

Non-Association of Driver Alterations in PTEN with Differential Gene Expression and Gene Methylation in IDH1 Wildtype Glioblastomas

open access: yesBrain Sciences, 2023
During oncogenesis, alterations in driver genes called driver alterations (DAs) modulate the transcriptome, methylome and proteome through oncogenic signaling pathways.
Mrinmay Kumar Mallik   +2 more
doaj   +1 more source

Integration of Transcriptome and Methylome Highlights the Roles of Cell Cycle and Hippo Signaling Pathway in Flatfish Sexual Size Dimorphism

open access: yesFrontiers in Cell and Developmental Biology, 2021
Sexual size dimorphism (SSD) is the difference in segments or body size between sexes prevalent in various species. Understanding the genetic architecture of SSD has remained a significant challenge owing to the complexity of growth mechanisms and the ...
Na Wang   +23 more
doaj   +1 more source

Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome

open access: yesEpigenetics, 2022
Few recurrent DNA mutations are seen in aggressive canine B cell lymphomas (cBCL), suggesting other frequent drivers. The methylated island recovery assay (MIRA-seq) or methylated CpG-binding domain sequencing (MBD-seq) was used to define the genome-wide
Shirley Chu   +3 more
doaj   +1 more source

Whole‐genome DNA methylation patterns of Oryza sativa (L.) and Oryza glumaepatula (Steud) genotypes associated with aluminum response

open access: yesPlant Direct, 2022
Epigenetic mechanisms in crops have emerged as a fundamental factor in plant adaptation and acclimation to biotic and abiotic stresses. Among described epigenetic mechanisms, DNA methylation has been defined as the most studied epigenetic modification ...
Jenny Johana Gallo‐Franco   +5 more
doaj   +1 more source

Differences in the Accessory Genomes and Methylomes of Strains of Streptococcus equi subsp. equi and of Streptococcus equi subsp. zooepidemicus Obtained from the Respiratory Tract of Horses from Texas

open access: yesMicrobiology Spectrum, 2022
Streptococcus equi subsp. equi (SEE) is a host-restricted equine pathogen considered to have evolved from Streptococcus equi subsp. zooepidemicus (SEZ). SEZ is promiscuous in host range and is commonly recovered from horses as a commensal.
Ellen Ruth A. Morris   +4 more
doaj   +1 more source

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