Results 41 to 50 of about 26,277 (245)

The Methylome of Vertebrate Sex Chromosomes [PDF]

Genes, 2018
DNA methylation is a key epigenetic modification in vertebrate genomes known to be involved in the regulation of gene expression, X chromosome inactivation, genomic imprinting, chromatin structure, and control of transposable elements. DNA methylation is common to all eukaryote genomes, but we still lack a complete understanding of the variation in DNA
Waters, SA, Capraro, A, McIntyre, KL, Graves, JAM, Waters, PD   +4 more
openaire   +3 more sources

VerenaDietrich/Spermatogenesis-Methylome: final version for manuscript

, 2023
No description ...
Verena Dietrich
core   +1 more source

Novel Identification of Bacterial Epigenetic Regulations Would Benefit From a Better Exploitation of Methylomic Data

Frontiers in Microbiology, 2021
DNA methylation can be part of epigenetic mechanisms, leading to cellular subpopulations with heterogeneous phenotypes. While prokaryotic phenotypic heterogeneity is of critical importance for a successful infection by several major pathogens, the exact ...
Amaury Payelleville, Amaury Payelleville, Julien Brillard   +2 more
doaj   +1 more source

Prodigious plant methylomes [PDF]

Genome Biology, 2016
Schmitz and colleagues recently investigated DNA methylation patterns in diverse flowering plant species, finding substantial variation in the extent and distribution of methylation in angiosperms.Please see related Research article: http://www.doi.org/10.1186/s13059-016-1059-0.
openaire   +4 more sources

Intraspecific epigenomics divergence in brown bears (Ursus arctos): insights from genome-wide DNA methylation patterns

Frontiers in Ecology and Evolution
Epigenetic mechanisms such as methylation can influence gene expression and play a crucial role in the adaptation to local environmental conditions, thereby introducing non-genetic variability within species.
Paolo Colangelo, Paolo Colangelo, Ian Marc Bonapace, Laura Gramolini, Emanuela Solano, Emanuela Solano, Elisa Desiato, Paolo Franchini, Leonardo Gentile, Roberto Guadagnini, Oddmund Kleven, Jonas Kindberg, Jonas Kindberg, Alexander Kopatz, Paolo Ciucci   +14 more
doaj   +1 more source

Identification of Putative Markers of Non-infectious Bud Failure in Almond [Prunus dulcis (Mill.) D.A. Webb] Through Genome Wide DNA Methylation Profiling and Gene Expression Analysis in an Almond × Peach Hybrid Population

Frontiers in Plant Science, 2022
Almond [Prunus dulcis (Mill.) D.A. Webb] is an economically important nut crop susceptible to the genetic disorder, Non-infectious Bud Failure (NBF). Despite the severity of exhibition in several prominent almond cultivars, no causal mechanism has been ...
Katherine M. D’Amico-Willman, Gina M. Sideli, Brian J. Allen, Elizabeth S. Anderson, Thomas M. Gradziel, Jonathan Fresnedo-Ramírez, Jonathan Fresnedo-Ramírez   +6 more
doaj   +1 more source

Effects of micronutrient supplementation on performance and epigenetic status in dairy cows

Animal, 2020
The postpartum period is crucial in dairy cows and is marked by major physiological and metabolic changes that affect milk production, immune response and fertility.
M. Gasselin, M. Boutinaud, A. Prézelin, P. Debournoux, M. Fargetton, E. Mariani, J. Zawadzki, H. Kiefer, H. Jammes   +8 more
doaj   +1 more source

Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy

Frontiers in Oncology, 2022
Epithelial ovarian carcinoma (EOC) is known for high mortality due to diagnosis at advanced stages and frequent therapy resistance. Previous findings suggested that the DNA repair system is involved in the therapeutic response of cancer patients and DNA ...
Karolina Seborova, Karolina Seborova, Viktor Hlavac, Viktor Hlavac, Petr Holy, Petr Holy, Petr Holy, Sunniva S. Bjørklund, Thomas Fleischer, Lukas Rob, Martin Hruda, Jiri Bouda, Marcela Mrhalova, Mohammad Moufaq Khatar Al Obeed Allah, Pavel Vodicka, Pavel Vodicka, Pavel Vodicka, Ondrej Fiala, Ondrej Fiala, Pavel Soucek, Pavel Soucek, Vessela N. Kristensen, Ludmila Vodickova, Ludmila Vodickova, Ludmila Vodickova, Radka Vaclavikova, Radka Vaclavikova   +26 more
doaj   +1 more source

Epigenetic therapies by targeting aberrant histone methylome in AML:molecular mechanisms, current preclinical and clinical development [PDF]

, 2016
While the current epigenetic-drug development is still largely restricted to target DNA methylome, emerging evidence indicates that histone methylome is indeed another major epigenetic determinant for gene expression and frequently deregulated in acute ...
So, Chi Wai Eric, Tsai, Chiou-Tsun
core   +7 more sources

Identification and Mechanism of Action of the Global Secondary Metabolism Regulator SaraC in Stereum hirsutum

Microbiology Spectrum, 2022
DNA methylation is an important factor in the regulation of gene expression. In analyzing genomic data of Stereum hirsutum FP-91666, we found a hypothetical bifunctional transcription regulator/O6Meguanine-DNA methyltransferase (named SaraC), which is ...
Qian-Yi Hu, Xue-Juan Pu, Guo-Hong Li, Chun-Qiang Li, Hong-Mei Lei, Ke-Qin Zhang, Pei-Ji Zhao   +6 more
doaj   +1 more source