Results 31 to 40 of about 37,526 (188)

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma [PDF]

, 2015
Accurate assessment of neuroblastoma outcome prediction remains challenging. Therefore, this study aims at establishing novel prognostic tumor DNA methylation biomarkers.
, Berbegall, Ana P., Bienertova-Vasku, Julie, Bown, Nick, Cannoodt, Robrecht, Clément, Nathalie, Combaret, Valérie, De Preter, Katleen, De Wilde, Bram, Decock, Anneleen, Haber, Michelle, Hoyoux, Claire, Laureys, Geneviève, Murray, Jayne, Noguera, Rosa, Ongenaert, Maté, Pierron, Gaelle, Schleiermacher, Gudrun, Schulte, Johannes H., Speleman, Frank, Stallings, Ray L., Tweddle, Deborah A., Van Roy, Nadine, Vandesompele, Jo, Verniers, Kimberly   +24 more
core   +2 more sources

Trisomy 21 alters DNA methylation in parent-of-origin-dependent and independent manners [PDF]

, 2016
The supernumerary chromosome 21 in Down syndrome differentially affects the methylation statuses at CpG dinucleotide sites and creates genome-wide transcriptional dysregulation of parental alleles, ultimately causing diverse pathologies.
Alves da Silva, Antônio Francisco, Biselli-Périco, Joice Matos, Chuva de Sousa Lopes, Susana Marina, Fernandes, Maria Gomes, Francisco Junior, Ronaldo da Silva, Lopes Rios, Álvaro Fabricio, Machado, Douglas Terra, Machado, Filipe Brum, Medina-Acosta, Enrique, Mozer Rodrigues, Pedro Thyago, Pavarino, Érika Cristina, Santos-Rebouças, Cíntia Barros, Zampieri, Bruna Lancia   +12 more
core   +3 more sources

DNA Hydroxymethylation at the Interface of the Environment and Nonalcoholic Fatty Liver Disease. [PDF]

, 2019
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent forms of chronic liver disorders among adults, children, and adolescents, and a growing epidemic, worldwide.
Besaratinia, Ahmad, Tommasi, Stella
core   +1 more source

Insights into the role of DNA methylation in diatoms by genome-wide profiling in Phaeodactylum tricornutum [PDF]

, 2013
DNA cytosine methylation is a widely conserved epigenetic mark in eukaryotes that appears to have critical roles in the regulation of genome structure and transcription.
Ahmed, Ikhlak, Allen, Andrew, Bhavsar, Jaysheel, Bondurant, Sandra Splinter, Bowler, Chris, Creasy, Todd, Crom, Stéphane Le, Farrant, Gregory K., Lin, Xin, Maumus, Florian, O'Brien, Kimberly, Olson, Sue A., Rabinowicz, Pablo D., Rayko, Edda, Rivarola, Maximo Lisandro, Sengamalay, Naomi A., Sgro, Jean-Yves, Smith, Andrew D., Sussman, Michael R., Tallon, Luke J., Tirichine, Leïla, Veluchamy, Alaguraj   +21 more
core   +2 more sources

Remodeling of the methylation landscape in breast cancer metastasis. [PDF]

PLoS ONE, 2014
The development of breast cancer metastasis is accompanied by dynamic transcriptome changes and dramatic alterations in nuclear and chromatin structure. The basis of these changes is incompletely understood.
Marsha Reyngold, Sevin Turcan, Dilip Giri, Kasthuri Kannan, Logan A Walsh, Agnes Viale, Marija Drobnjak, Linda T Vahdat, William Lee, Timothy A Chan   +9 more
doaj   +1 more source

Plant roots : New challenges in a changing world [PDF]

, 2016
Peer ...
Price, Adam H.
core   +1 more source

Genetic alterations in gliosarcoma and giant cell glioblastoma [PDF]

, 2015
The majority of glioblastomas develop rapidly with a short clinical history (primary glioblastoma IDH wild-type), whereas secondary glioblastomas progress from diffuse astrocytoma or anaplastic astrocytoma.
ANTONELLI, MANILA, Capper, David, GIANGASPERO, FELICE, Kleihues, Paul, Mittelbronn, Michel, Nonoguchi, Naosuke, Oh, Ji Eun, Ohgaki, Hiroko, Ohta, Takashi, Paulus, Werner, Pierscianek, Daniela, Satomi, Kaishi, Sure, Ulrich, Vital, Anne   +13 more
core   +1 more source

Intraspecific epigenomics divergence in brown bears (Ursus arctos): insights from genome-wide DNA methylation patterns

Frontiers in Ecology and Evolution
Epigenetic mechanisms such as methylation can influence gene expression and play a crucial role in the adaptation to local environmental conditions, thereby introducing non-genetic variability within species.
Paolo Colangelo, Paolo Colangelo, Ian Marc Bonapace, Laura Gramolini, Emanuela Solano, Emanuela Solano, Elisa Desiato, Paolo Franchini, Leonardo Gentile, Roberto Guadagnini, Oddmund Kleven, Jonas Kindberg, Jonas Kindberg, Alexander Kopatz, Paolo Ciucci   +14 more
doaj   +1 more source

Effects of micronutrient supplementation on performance and epigenetic status in dairy cows

Animal, 2020
The postpartum period is crucial in dairy cows and is marked by major physiological and metabolic changes that affect milk production, immune response and fertility.
M. Gasselin, M. Boutinaud, A. Prézelin, P. Debournoux, M. Fargetton, E. Mariani, J. Zawadzki, H. Kiefer, H. Jammes   +8 more
doaj   +1 more source

Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes. [PDF]

, 2017
ObjectiveTo determine whether differentially methylated CpGs in synovium-derived fibroblast-like synoviocytes (FLS) of patients with rheumatoid arthritis (RA) were also differentially methylated in RA peripheral blood (PB) samples.MethodsFor this study ...
Barcellos, Lisa F, Cole, Michael, Criswell, Lindsey A, Firestein, Gary S, Graf, John, Halperin, Eran, Harrison, Ruby, Holingue, Calliope, Link, Thomas, Quach, Diana, Quach, Hong L, Rahmani, Elior, Rhead, Brooke, Shah, Khooshbu, Shao, Xiaorong, Sinclair, Elizabeth, Wang, Wei   +16 more
core   +1 more source