Results 11 to 20 of about 37,526 (188)

Impact of Plasmodium falciparum infection on DNA methylation of circulating immune cells

Frontiers in Genetics, 2023
The regulation of immune cell responses to infection is a complex process that involves various molecular mechanisms, including epigenetic regulation. DNA methylation has been shown to play central roles in regulating gene expression and modulating cell ...
Dareen Almojil, Aïssatou Diawara, Issiaka Soulama, Mame Massar Dieng, Vinu Manikandan, Samuel S. Sermé, Salif Sombié, Amidou Diarra, Aissata Barry, Sam Aboubacar Coulibaly, Sodiomon B. Sirima, Youssef Idaghdour   +11 more
doaj   +1 more source

Simultaneous profiling of transcriptome and DNA methylome from a single cell. [PDF]

, 2016
BackgroundSingle-cell transcriptome and single-cell methylome technologies have become powerful tools to study RNA and DNA methylation profiles of single cells at a genome-wide scale. A major challenge has been to understand the direct correlation of DNA
An, Qin, Du, Guizhen, Fan, Guoping, Hu, Ganlu, Hu, Youjin, Huang, Kevin, Wang, Cun-Yu, Xue, Jinfeng, Xue, Zhigang, Zhu, Xianmin   +9 more
core   +3 more sources

Massive Loss of DNA Methylation in Nitrogen-, but Not in Phosphorus-Deficient Zea mays Roots Is Poorly Correlated With Gene Expression Differences

Frontiers in Plant Science, 2018
DNA methylation in plants plays a role in transposon silencing, genome stability and gene expression regulation. Environmental factors alter the methylation pattern of DNA and recently nutrient stresses, such as phosphate starvation, were shown to alter ...
Svenja Mager, Uwe Ludewig
doaj   +1 more source

Joint profiling of DNA methylation and chromatin architecture in single cells. [PDF]

, 2019
We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC reveals coordinated DNA methylation status between distal genomic segments that are in spatial proximity in the ...
AD Schmitt, B Diedenhofen, Bing Ren, C Luo, E Lieberman-Aiden, E Rodríguez-Carballo, F Lyko, Guoqiang Li, IM Flyamer, J Gribnau, JesseR Dixon, JR Dixon, JU Guo, M Iurlaro, Manolis Kellis, Miao Yu, Naoki Kubo, NC Durand, O Schwartzman, R Lister, R Shoemaker, Rongxin Fang, S Guo, SA Smallwood, SuhasSP Rao, T Nagano, T Yang, V Ramani, Y Liu, Y Liu, Yanxiao Zhang, Yaping Liu   +31 more
core   +1 more source

Identification of DNA-Methylated CpG Islands Associated With Gene Silencing in the Adult Body Tissues of the Ogye Chicken Using RNA-Seq and Reduced Representation Bisulfite Sequencing

Frontiers in Genetics, 2019
DNA methylation is an epigenetic mark that plays an essential role in regulating gene expression. CpG islands are DNA methylations regions in promoters known to regulate gene expression through transcriptional silencing of the corresponding gene.
Won-Jun Lim, Won-Jun Lim, Kyoung Hyoun Kim, Kyoung Hyoun Kim, Jae-Yoon Kim, Jae-Yoon Kim, Seongmun Jeong, Namshin Kim, Namshin Kim   +8 more
doaj   +1 more source

DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing [PDF]

, 2016
Comprehensive genome-wide DNA methylation studies in neuroblastoma (NB), a childhood tumor that originates from precursor cells of the sympathetic nervous system, are scarce. Recently, we profiled the DNA methylome of 102 well-annotated primary NB tumors
Decock, Anneleen, Ongenaert, Maté, Speleman, Franki, Van Criekinge, Wim, Vandesompele, Jo   +4 more
core   +1 more source

Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis [PDF]

, 2019
© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Xu, X., Li, G., Li, C., Zhang, J., Wang, Q., Simmons, D. K., Chen, X., Wijesena, N., Zhu, W., Wang, Z.,
Aluru, Neelakanteswar, Chen, Xuepeng, Ci, Weimin, Ju, Bao, Li, Congru, Li, Guoqiang, Liu, Jiang, Lu, Xuemei, Martindale, Mark Q., Oliveri, Paola, Simmons, David K., Wang, Qian-fei, Wang, Qiang, Wang, Zhanyang, Wang, Zhenhua, Wijesena, Naveen, Xu, Xiaocui, Yu, Daqi, Zhang, Jing, Zhang, Yong E., Zhu, Wei   +20 more
core   +2 more sources

Analyses of methylomes derived from Meso-American common bean (Phaseolus vulgaris L.) using MeDIP-seq and whole genome sodium bisulfite-sequencing

Frontiers in Plant Science, 2016
Common bean (Phaseolus vulgaris L.) is economically important for its high protein, fiber, and micronutrient contents, with a relatively small genome size of ~587 Mb. Common bean is genetically diverse with two major gene pools, Meso-American and Andean.
Mollee eCrampton, Venkateswara eSripathi, Khwaja eHossain, Venu (Kal) eKalavacharla   +3 more
doaj   +1 more source

Genome-wide DNA methylation profiling in human breast tissue by Illumina TruSeq methyl capture EPIC sequencing and infinium methylationEPIC beadchip microarray

Epigenetics, 2021
A newly-developed platform, the Illumina TruSeq Methyl Capture EPIC library prep (TruSeq EPIC), builds on the content of the Infinium MethylationEPIC Beadchip Microarray (EPIC-array) and leverages the power of next-generation sequencing for targeted ...
Nan Lin, Jinpeng Liu, James Castle, Jun Wan, Aditi Shendre, Yunlong Liu, Chi Wang, Chunyan He   +7 more
doaj   +1 more source

Comparison of Yersinia enterocolitica DNA Methylation at Ambient and Host Temperatures

Epigenomes, 2023
Pathogenic bacteria recognize environmental cues to vary gene expression for host adaptation. Moving from ambient to host temperature, Yersinia enterocolitica responds by immediately repressing flagella synthesis and inducing the virulence plasmid (pYV ...
Dustin J. Van Hofwegen, Carolyn J. Hovde, Scott A. Minnich   +2 more
doaj   +1 more source