Results 21 to 30 of about 26,277 (245)

Impact of Plasmodium falciparum infection on DNA methylation of circulating immune cells

Frontiers in Genetics, 2023
The regulation of immune cell responses to infection is a complex process that involves various molecular mechanisms, including epigenetic regulation. DNA methylation has been shown to play central roles in regulating gene expression and modulating cell ...
Dareen Almojil, Aïssatou Diawara, Issiaka Soulama, Mame Massar Dieng, Vinu Manikandan, Samuel S. Sermé, Salif Sombié, Amidou Diarra, Aissata Barry, Sam Aboubacar Coulibaly, Sodiomon B. Sirima, Youssef Idaghdour   +11 more
doaj   +1 more source

An Analysis of Methylome Evolution in Primates [PDF]

Molecular Biology and Evolution, 2021
Abstract Although the investigation of the epigenome becomes increasingly important, still little is known about the long-term evolution of epigenetic marks and systematic investigation strategies are still lacking. Here, we systematically demonstrate the transfer of classic phylogenetic methods such as maximum likelihood based on ...
Arne Sahm, Philipp Koch, Steve Horvath, Steve Hoffmann   +3 more
openaire   +2 more sources

Massive Loss of DNA Methylation in Nitrogen-, but Not in Phosphorus-Deficient Zea mays Roots Is Poorly Correlated With Gene Expression Differences

Frontiers in Plant Science, 2018
DNA methylation in plants plays a role in transposon silencing, genome stability and gene expression regulation. Environmental factors alter the methylation pattern of DNA and recently nutrient stresses, such as phosphate starvation, were shown to alter ...
Svenja Mager, Uwe Ludewig
doaj   +1 more source

Identification of DNA-Methylated CpG Islands Associated With Gene Silencing in the Adult Body Tissues of the Ogye Chicken Using RNA-Seq and Reduced Representation Bisulfite Sequencing

Frontiers in Genetics, 2019
DNA methylation is an epigenetic mark that plays an essential role in regulating gene expression. CpG islands are DNA methylations regions in promoters known to regulate gene expression through transcriptional silencing of the corresponding gene.
Won-Jun Lim, Won-Jun Lim, Kyoung Hyoun Kim, Kyoung Hyoun Kim, Jae-Yoon Kim, Jae-Yoon Kim, Seongmun Jeong, Namshin Kim, Namshin Kim   +8 more
doaj   +1 more source

Multi-omics integration strategies for animal epigenetic studies — A review [PDF]

Animal Bioscience, 2021
Genome-wide studies provide considerable insights into the genetic background of animals; however, the inheritance of several heritable factors cannot be elucidated.
Do-Young Kim, Jun-Mo Kim
doaj   +1 more source

Computational Methods for Single-cell DNA Methylome Analysis

, 2023
Dissecting intercellular epigenetic differences is key to understanding tissue heterogeneity. Recent advances in single-cell DNA methylome profiling have presented opportunities to resolve this heterogeneity at the maximum resolution.
Wanding Zhou, Waleed Iqbal
core   +1 more source

Mining methylome databases [PDF]

Trends in Genetics, 2013
A confounding issue in deciphering the methylome is the recently observed phenomenon of non-CpG methylation (i.e., methylation at CpA, CpT, and CpC). Intriguingly, evidence suggests that methylation of up to 25% of cytosines occurs in a non-CpG context [12xHuman DNA methylomes at base resolution show widespread epigenomic differences. Lister, R. et al.
O'Rourke, Colm J, Murphy, Therese M, Hollywood, Donal, Perry, Antoinette S   +3 more
openaire   +3 more sources

Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of Repeats [PDF]

, 2012
PMCID: PMC3315563This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Vardhman K. Rakyan (175834), Smith Paul, Silvana Debernardi, Bryan D. Young (46738), Gael Molloy (46735), Sabah Khalid, Sabah Khalid (175832), Rakyan, VK, Molloy, Gael, Khalid, Sabah, Marzec, J, Marwa H. Saied (175830), Down Thomas A., Molloy Gael, Marzec Jacek, Gael Molloy, Raghavan Manoj, Raghavan, Manoj, Young, BD, Khalid Sabah, Debernardi, Silvana, Vardhman K Rakyan, Manoj Raghavan (175835), Down, Thomas A, Jacek Marzec (175831), Raghavan, M, Young, Bryan D, Marwa H Saied, Bryan D Young, Debernardi Silvana, Smith, P, Debernardi, S, Marzec, Jacek, Jacek Marzec, Rakyan, Vardhman K, Saied Marwa H., Molloy, G, Paul Smith (175833), Thomas A. Down (8471), Paul Smith, Saied, Marwa H, Rakyan Vardhman K., Manoj Raghavan, Young Bryan D., Smith, Paul, Down, TA, Saied, MH, Khalid, S, Silvana Debernardi (46739), Thomas A Down   +49 more
core   +2 more sources

Analyses of methylomes derived from Meso-American common bean (Phaseolus vulgaris L.) using MeDIP-seq and whole genome sodium bisulfite-sequencing

Frontiers in Plant Science, 2016
Common bean (Phaseolus vulgaris L.) is economically important for its high protein, fiber, and micronutrient contents, with a relatively small genome size of ~587 Mb. Common bean is genetically diverse with two major gene pools, Meso-American and Andean.
Mollee eCrampton, Venkateswara eSripathi, Khwaja eHossain, Venu (Kal) eKalavacharla   +3 more
doaj   +1 more source

The methylomes of six bacteria [PDF]

Nucleic Acids Research, 2012
Six bacterial genomes, Geobacter metallireducens GS-15, Chromohalobacter salexigens, Vibrio breoganii 1C-10, Bacillus cereus ATCC 10987, Campylobacter jejuni subsp. jejuni 81-176 and C. jejuni NCTC 11168, all of which had previously been sequenced using other platforms were re-sequenced using single-molecule, real-time (SMRT) sequencing specifically to
Murray, Iain A., Clark, Tyson A., Morgan, Richard D., Boitano, Matthew, Anton, Brian P., Luong, Khai, Fomenkov, Alexey, Turner, Stephen W., Korlach, Jonas, Roberts, Richard J.   +9 more
openaire   +2 more sources