Results 61 to 70 of about 26,277 (245)

Increased methylome distances within scalp-derived fibroblasts.

, 2016
Y-axis: methylome (Euclidean) distance between pairs of samples stratified by cell and tissue types. CD4T: CD4+ T-cell, NK: natural killer cell, Mono: monocyte, NeuN+: neuronal DLPC cell, NeuN-: non-neuronal DLPFC cell.
Joshua G. Chenoweth (2512222), Daniel R. Weinberger (83125), Anna Brandtjen (2512225), Michelle I. Mighdoll (2512216), Ran Tao (81449), Andrew E. Jaffe (132950), Yankai Jia (2476102), John D. Genova (2512210), Joel E. Kleinman (67665), Thomas M. Hyde (67664), Ronald D. McKay (2512219), Nikolay A. Ivanov (2512213)   +11 more
core   +1 more source

Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia [PDF]

, 2015
Although children with acute lymphoblastic leukemia (ALL) generally have a good outcome, some patients do relapse and survival following relapse is poor.
Mitchell, Chris D, Steven C Clifford (779057), Gabriel, Alem, Clifford, Steven, Schwalbe, Edward C, Mitchell, Chris, Nakjang, Sirintra, Alem S Gabriel (779049), Clifford, Steven C, Lafta, Fadhel M, Strathdee, Gordon, Simon J Cockell (779052), Kinsey, Sally, Vikki Rand (779056), Iliasova, Alice, Christine J Harrison (779061), Schwalbe, Ed, Harrison, Christine, Anthony V Moorman (779062), Lafta, Fadhel, Kinsey, Sally E, Sally E Kinsey (779058), Chris D Mitchell (779059), Vora, Ajay, Cockell, Simon J, Rand, Vikki, Edward C Schwalbe (779051), Gordon Strathdee (779063), Enshaei, Amir, Sirintra Nakjang (124590), Harris, Christine J, Gabriel, Alem S, Moorman, Anthony, Amir Enshaei (779054), Fadhel M Lafta (779050), Claire Schwab (779055), Moorman, Anthony V, Rand, Vikki; id_orcid, Schwab, Claire, Ajay Vora (779060), Cockell, Simon, Alice Iliasova (779053)   +41 more
core   +1 more source

Epigenetic insights into creep-feeding: methylation profiling of Longissimus thoracis muscle at weaning in crossbred cattle

Frontiers in Animal Science
IntroductionThis study investigated the impact of creep-feeding supplementation on the genome methylation of the Longissimus thoracis (LT) muscle in crossbred beef cattle (Bos taurus × Bos indicus).MethodsThe experiment involved 48 uncastrated F1 Angus ...
Lucas Farias Rodrigues, German Dario Ramírez-Zamudio, German Dario Ramírez-Zamudio, Guilherme Luis Pereira, Guilherme Luis Pereira, Juliana Akamine Torrecilhas, Lucas Augustinho Trevisan, Otávio Rodrigues Machado Neto, Otávio Rodrigues Machado Neto, Luis Artur Loyola Chardulo, Luis Artur Loyola Chardulo, Welder Angelo Baldassini, Welder Angelo Baldassini, Rogério Abdallah Curi, Rogério Abdallah Curi   +14 more
doaj   +1 more source

The methylome of motile cilia

Molecular Biology of the Cell
Cilia are highly complex motile, sensory, and secretory organelles that contain perhaps 1000 or more distinct protein components, many of which are subject to various posttranslational modifications such as phosphorylation, N-terminal acetylation, and proteolytic processing.
Stephen M. King, Miho Sakato-Antoku, Ramila S. Patel-King, Jeremy L. Balsbaugh   +3 more
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

VerenaDietrich/Spermatogenesis-Methylome: final version for manuscript with licence

, 2023
No description ...
Verena Dietrich
core   +1 more source

Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations [PDF]

, 2017
DNA methylation is an epigenetic mark that is indispensable for mammalian development and occurs at cytosine residues throughout the genome (the "methylome").
Butcher, LM, Beck, S
core   +1 more source

Epstein-Barr virus (EBV)-host cell interactions: an epigenetic dialogue?

Frontiers in Genetics, 2014
Epstein-Barr virus (EBV) is associated with diverse lymphoid and epithelial malignancies. Their molecular pathogenesis is accompanied by epigenetic alterations which are distinct for each of them.
Hans Helmut Niller, Kalman eSzenthe, Janos eMinarovits   +2 more
doaj   +1 more source

Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems

, 2020
Aim: We conducted a methylome-wide association study to examine associations between DNA methylation in whole blood and central adiposity and body fat distribution, measured as waist circumference, waist-to-hip ratio and waist-to-height ratio adjusted ...
Huang, R-C (15628547), Gondalia, R (15717521), Liu, C-T (15567068), Guan, W (15670142), Bressler, J (15605804), Mori, MA (15717548), Beilin, LJ (15501392), Cupples, LA (15567371), Conneely, K (15717545), Lim, E (15687272), Heard-Costa, N (15717533), Fernandez-Rhodes, L (15717527), Howard, AG (15717554), Phillip Melton (14744191), Stewart, JD (15717539), Demerath, E (15717530), Li, Y (15494459), Gordon-Larsen, P (15717551), Boerwinkle, E (15595487), Whitsel, EA (15717524), Hou, L (15621599), Grove, ML (15670148), Justice, AE (15656651), Chittoor, G (15717518), Baccarelli, A (15717542), Fornage, M (15555863), North, KE (15667877), Levy, D (15717536)   +27 more
core  

Enhancing resolution of natural methylome reprogramming behavior in plants

, 2018
BackgroundNatural methylome reprogramming within chromatin involves changes in local energy landscapes that are subject to thermodynamic principles. Signal detection permits the discrimination of methylation signal from dynamic background noise that is ...
Sally A. Mackenzie, Jose R Barreras, Xiaodong Yang, Robersy Sanchez, Hardik Kundariya   +4 more
core   +1 more source