Results 71 to 80 of about 26,277 (245)
The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01
Journal of FungiGerronema lapidescens (Lei Wan), a valued medicinal basidiomycete traditionally employed for antiparasitic and digestive ailments, faces severe conservation threats due to unsustainable wild harvesting and the absence of reliable cultivation protocols ...
Yanming Qiao +9 more
doaj +1 more source
mmiddleton/mmiddleton-fish546: O.mykiss sperm methylome
, 2016 <p>This is the completed version of my project learning bioinformatics skills and using them to investigate the methylome of a sperm sample from steelhead trout.</p ...
mmiddleton
core +1 more source
Epigenetic profiling of preterm birth: a dual-tissue methylation patterns using long-read sequencing
Frontiers in Epigenetics and EpigenomicsIntroductionPreterm birth (PTB), a leading cause of neonatal morbidity and mortality, arises from complex maternal-fetal interactions with multifactorial origins.
BalaSubramani Gattu Linga +41 more
doaj +1 more source
Advanced Science, EarlyView.We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong +19 more
wiley +1 more source
Simultaneous profiling of transcriptome and DNA methylome from a single cell [PDF]
, 2016 BackgroundSingle-cell transcriptome and single-cell methylome technologies have become powerful tools to study RNA and DNA methylation profiles of single cells at a genome-wide scale. A major challenge has been to understand the direct correlation of DNA
Zhigang Xue +19 more
core +1 more source
The Arabidopsis DNA methylome is stable under transgenerational drought stress
, 2020 Improving the responsiveness, acclimation, and memory of plants to abiotic stress holds substantive potential for improving agriculture. An unresolved question is the involvement of chromatin marks in the memory of agriculturally relevant stresses.
Eichten, Steven +3 more
core +2 more sources
EpigeneticsA global priority for ameliorating male factor infertility includes identification of environmental factors and mechanisms that impact sperm function. Detection of endocrine disrupting chemicals (EDC) in seminal plasma and within the female reproductive ...
Muhammad S. Siddique +6 more
doaj +1 more source
Current Research on Molecular Biomarkers for Colorectal Cancer in Stool Samples
Biology, 2023 Colorectal cancer (CRC) is one of the most diagnosed cancers worldwide, with a high incidence and mortality rate when diagnosed late. Currently, the methods used in healthcare to diagnose CRC are the fecal occult blood test, flexible sigmoidoscopy, and ...
Patricio Órdenes +3 more
doaj +1 more source
Genetic Perturbation of the Maize Methylome [PDF]
The Plant Cell, 2014 DNA methylation can play important roles in the regulation of transposable elements and genes. A collection of mutant alleles for 11 maize (Zea mays) genes predicted to play roles in controlling DNA methylation were isolated through forward- or reverse-genetic approaches. Low-coverage whole-genome bisulfite sequencing and high-coverage sequence-capture
Qing Li +18 more
openaire +3 more sources
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
Advanced Science, EarlyView.The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source