Results 141 to 150 of about 60,956 (264)

Rumen Mycobiome Thiamine Metabolism Contributes to Subacute Rumen Acidosis Tolerance in Goats Through Enhancing Epithelial Cell Proliferation via IGFBP2/IGF1 Axis Activation

Exploration, EarlyView.
Schematic illustration of the mechanism underlying the differences between SARA‐susceptible and SARA‐tolerant dairy goats fed a high‐concentrate diet. SARA‐susceptible goats (HCS) exhibit low rumen pH and metabolic decline, characterized by epithelial inflammation.
Jingyi Xu, Xiaodong Chen, Yi Ma, Jianrong Ren, Guanghao Xu, Peilin Zhang, Wenhao Jia, Quanqiu Deng, Yuquan Xiao, Junhu Yao, Shengru Wu   +10 more
wiley   +1 more source

Intraspecific genome size variation is attributed to adaptive silencing of transposable elements in Hordeum species. [PDF]

Mol Biol Evol
Potapenko E, Shermeister B, Mandel T, Hübner S.   +3 more
europepmc   +1 more source

Mapping Alkyne Chemical Space—Classifying the Reactivity of Alkynes in Semihydrogenation and beyond Using a Data Science Framework

Helvetica Chimica Acta, EarlyView.
A data science framework integrating DFT featurization and hierarchical clustering was used to map the chemical space of over 2700 alkynes into six subsets before using experimental data for Ni3Zn‐catalyzed semihydrogenation and applying a logistic regression model to categorize substrates by reactivity.
Jordan De Jesus Silva, Scott R. Docherty, Jasper Clarysse, Maksym Yarema, Vanessa Wood, Christophe Copéret   +5 more
wiley   +1 more source

Chromosome-scale Genome Assembly of the Most Abundant Ectomycorrhizal Fungus Cenococcum Geophilum Reveals Massive TE Expansion and RIP Defense Mechanism. [PDF]

Genome Biol Evol
Dauphin B, Baril T, Morin E, Oggenfuss U, Pfister S, De Freitas Pereira M, Grigoriev IV, Kohler A, Martin F, Croll D, Peter M.   +10 more
europepmc   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, EarlyView.
What's New? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Expression of endogenous retroviral elements is associated with extracellular matrix remodeling in prostate cancer. [PDF]

Mob DNA
Williams EC, Mayarata DR, Horvath A, Chiappinelli KB, Shibata M.   +4 more
europepmc   +1 more source

Diversity, transfer potential, and transcriptional activity of virus‐carried antibiotic resistance genes in global estuaries

iMetaOmics, EarlyView.
Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo, Xiyang Dong, Jia‑Ling Li, Ji‐Cheng Yao, Ziqi Peng, Qi Li, Zi‐Wen Yang, Yang Yuan, Wen‑Jun Li, Pandeng Wang   +9 more
wiley   +1 more source

Transcriptional response of transposable elements to thermal stress in the Antarctic fish Trematomus bernacchii. [PDF]

Sci Rep
Tittarelli E, Carotti E, Palladinelli C, Barucca M, Carducci F, Santovito G, Piva E, Canapa A, Biscotti MA.   +8 more
europepmc   +1 more source

Resistome flow in global landfill systems

iMetaOmics, EarlyView.
Global landfill systems represent key hubs of resistome, serving as dynamic reservoirs and amplifiers through plasmid‐driven gene mobility. Waste flows and environmental pathways sustain the transboundary resistome networks, accelerating resistance dissemination across ecosystems.
Wenqing Hong, Rui Zhang, Xiaoxing Lin, Yangqing Wang, Shu Yang, Farees ud din Mufti, Yuping Yao, Guowei Zhou, Chuanwu Xi, Weixi Shu, Gordon Price, Youcai Zhao, Liyan Song   +12 more
wiley   +1 more source

Haplotype-resolved chromosome-level genome assembly of creeping bentgrass, Agrostis stolonifera. [PDF]

Sci Data
Robbins MD, Park S, Bushman BS, Warnke SE, Barnaby JY.   +4 more
europepmc   +1 more source