Results 161 to 170 of about 256,848 (381)

Function and evolution of local repeats in the Firre locus

Nature Communications, 2016
Mammalian genomes contain multiple repetitive sequences such as transposable elements and local repeats. Here, the authors show that the conserved long non-coding RNA Firre contains repeats that act as nuclear retention signals and a DNA enhancer element.
Ezgi Hacisuleyman, Chinmay J. Shukla, Catherine L. Weiner, John L. Rinn   +3 more
doaj   +1 more source

Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations

Advanced Science, EarlyView.
This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu, Langqing Liu, Min Huang, Donglin Ruan, Rongrong Ding, Zebin Zhang, Enqin Zheng, Shiyuan Wang, Shaoxiong Deng, Xianglun Meng, Xinyan Cheng, Jiaxin Shi, Yingshan Yang, Fuchen Zhou, Sixiu Huang, Huaqiang Yang, Zicong Li, Gengyuan Cai, Zhenfang Wu, Jie Yang   +19 more
wiley   +1 more source

Transposable Elements and Their Epigenetic Regulation in Mental Disorders: Current Evidence in the Field

Frontiers in Genetics, 2019
Transposable elements (TEs) are highly repetitive DNA sequences in the human genome that are the relics of previous retrotransposition events. Although the majority of TEs are transcriptionally inactive due to acquired mutations or epigenetic processes ...
B. Misiak, L. Ricceri, M. Sąsiadek
semanticscholar   +1 more source

Nanoparticle Delivery of Antisense miR162 Inhibits Invasive Habitat Adaption of Alternanthera Philoxeroides

Advanced Science, EarlyView.
This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu, Erfeng Kou, Xiuzhen Liao, Ruiyi Qiu, Qi Tang, Huan Zhang, Yun Zheng, Ji Yang, Binglian Zheng   +8 more
wiley   +1 more source

Epigenetic regulation of repetitive DNA through mitotic asynchrony following double fertilization in angiosperms [PDF]

arXiv, 2013
Several recent studies show that companion cells in flowering plant gametophytes relax epigenetic control of transposable elements (TEs) to promote production of small RNA that presumably assist nearby reproductive cells in management of TEs. In light of this possibility, a closer look at the timing of cell division in relation to angiosperm double ...
arxiv  

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

Mechanisms underlying synergism between circularized tumor necrosis factor‐related apoptosis inducing ligand and bortezomib in bortezomib‐sensitive or ‐resistant myeloma cells

Hematological Oncology, Volume 40, Issue 5, Page 999-1008, December 2022., 2022
Abstract Mechanisms underlying interactions between a novel, clinically relevant circularized tumor necrosis factor‐related apoptosis inducing ligand (TRAIL) agonist, circularly permuted TRAIL (CPT) have been examined in multiple myeloma (MM) cells sensitive or resistant to bortezomib (BTZ).
Yun Leng, Xiaoyan Hu, Lin Li, Jewel Nkwocha, Toshihisa Satta, Kanika Sharma, Maciej Kmeiciak, Huixing Zhou, Zhiyao Zhang, Liang Zhou, Wenming Chen, Steven Grant   +11 more
wiley   +1 more source

Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages.

PLoS Biology, 2015
Small RNA pathways act at the front line of defence against transposable elements across the Eukaryota. In animals, Piwi interacting small RNAs (piRNAs) are a crucial arm of this defence.
Peter Sarkies, Murray E Selkirk, John T Jones, Vivian Blok, Thomas Boothby, Bob Goldstein, Ben Hanelt, Alex Ardila-Garcia, Naomi M Fast, Phillip M Schiffer, Christopher Kraus, Mark J Taylor, Georgios Koutsovoulos, Mark L Blaxter, Eric A Miska   +14 more
doaj   +1 more source

Transposable elements generate regulatory novelty in a tissue-specific fashion

BMC Genomics, 2018
Transposable elements (TE) are an important source of evolutionary novelty in gene regulation. However, the mechanisms by which TEs contribute to gene expression are largely uncharacterized.
M. Trizzino, A. Kapusta, Christopher D. Brown   +2 more
semanticscholar   +1 more source

Cytogenomic Characterization of Transposable Elements and Satellite DNA in Passiflora L. Species [PDF]

Genes
The species Passiflora alata, P. cincinnata, and P. edulis have great economic value due to the use of their fruits for human consumption. In this study, we compared the repetitive genome fractions of these three species. The compositions of the repetitive DNA of these three species’ genomes were analyzed using clustering and identification of the ...
Gonçalo Santos Silva, Margarete Magalhães Souza, Vanessa de Carvalho Cayres Pamponét, Fabienne Micheli, Cláusio Antônio Ferreira de Melo, Sárah Gomes de Oliveira, Eduardo Almeida Costa   +6 more
openaire   +4 more sources