Small RNAs, DNA methylation and transposable elements in wheat [PDF]
BMC Genomics, 2010 Background More than 80% of the wheat genome is composed of transposable elements (TEs). Since active TEs can move to different locations and potentially impose a significant mutational load, their expression is suppressed in the genome via small non ...
Matvienko Marta +7 more
doaj +9 more sources
Proliferation of Regulatory DNA Elements Derived from Transposable Elements in the Maize Genome [PDF]
Plant Physiology, 2018 Genomic regions free of nucleosomes, which are hypersensitive to DNase I digestion, are known as DNase I hypersensitive sites (DHSs) and frequently contain cis-regulatory DNA elements. To investigate their prevalence and characteristics in maize (Zea mays), we developed high-resolution genome-wide DHS maps using a modified DNase-seq technique.
Hainan Zhao +6 more
semanticscholar +4 more sources
Detection of DNA Methylation Changes Surrounding Transposable Elements
Bio-Protocol, 2013 Transposable elements (TEs) are a major component of all genomes, thus the epigenetic mechanisms controlling their activity is an important field of study.
Beery Yaakov, Khalil Kashkush
doaj +3 more sources
Satellite DNA and Transposable Elements in Seabuckthorn ( Hippophae rhamnoides ), a Dioecious Plant with Small Y and Large X Chromosomes [PDF]
Genome Biology and Evolution, 2017 Seabuckthorn (Hippophae rhamnoides) is a dioecious shrub commonly used in the pharmaceutical, cosmetic, and environmental industry as a source of oil, minerals and vitamins.
Janka Puterová +8 more
openalex +2 more sources
DNA methylation enables transposable element-driven genome expansion [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance We examined recent whole-genome data of 53 organisms and found that the substantial differences in their genome sizes can be largely explained by the proportion of transposable elements (TEs) within them.
Wanding Zhou +3 more
semanticscholar +4 more sources
Paired-End Mappability of Transposable Elements in the Human Genome [PDF]
Mobile DNA, 2019 Though transposable elements make up around half of the human genome, the repetitive nature of their sequences makes it difficult to accurately align conventional sequencing reads.
Han, Mira V., Sexton, Corinne E.
core +3 more sources
The epigenomic landscape of transposable elements across normal human development and anatomy [PDF]
Nature Communications, 2019 Transposable elements (TEs) have deposited functional regulatory elements throughout the human genome. Although most are silenced, certain TEs have been co-opted by the host.
Choudhary, Mayank N.K. +3 more
core +3 more sources
Regulation of transposable elements by DNA modifications [PDF]
Nature Reviews Genetics, 2019 Maintenance of genome stability requires control over the expression of transposable elements (TEs), whose activity can have substantial deleterious effects on the host. Chemical modification of DNA is a commonly used strategy to achieve this, and it has long been argued that the emergence of 5-methylcytosine (5mC) in many species was driven by the ...
Özgen Deniz, J. Frost, M. Branco
semanticscholar +4 more sources
PERSPECTIVE: TRANSPOSABLE ELEMENTS, PARASITIC DNA, AND GENOME EVOLUTION [PDF]
Evolution, 2001 The nature of the role played by mobile elements in host genome evolution is reassessed considering numerous recent developments in many areas of biology. It is argued that easy popular appellations such as "selfish DNA" and "junk DNA" may be either inaccurate or misleading and that a more enlightened view of the transposable element-host relationship ...
Margaret G. Kidwell, Damon Lisch
openalex +4 more sources
Mobilization of DNA transposable elements from lentiviral vectors [PDF]
Mobile Genetic Elements, 2011 With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
R. Bak, J. Mikkelsen
semanticscholar +5 more sources