Scientific Reports, 2022 Global changes in DNA methylation are observed in development and disease, and single-cell analyses are highlighting the heterogeneous regulation of these processes.
Kooper V. Hunt +7 more
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Comparative analysis of repeat content in plant genomes, large and small
Frontiers in Plant Science, 2023 The DNA Features pipeline is the analysis pipeline at EMBL-EBI that annotates repeat elements, including transposable elements. With Ensembl’s goal to stay at the cutting edge of genome annotation, we proved that this pipeline needed an update.
Joris Argentin +4 more
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Insertion sequence inversions mediated by ectopic recombination between terminal inverted repeats. [PDF]
PLoS ONE, 2010 Transposable elements are widely distributed and diverse in both eukaryotes and prokaryotes, as exemplified by DNA transposons. As a result, they represent a considerable source of genomic variation, for example through ectopic (i.e.
Alison Ling, Richard Cordaux
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Mobilization of DNA transposable elements from lentiviral vectors [PDF]
Mobile Genetic Elements, 2011 With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
Bak, Rasmus Otkjær +1 more
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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Nature Communications, 2020 Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei +2 more
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Transposable elements and circular DNAs [PDF]
Mobile Genetic Elements, 2016 Circular DNAs are extra-chromosomal fragments that become circularized by genomic recombination events. We have recently shown that yeast LTR elements generate circular DNAs through recombination events between their flanking long terminal repeats (LTRs).
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Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
PLoS ONE, 2012 Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
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Sex and the TEs: transposable elements in sexual development and function in animals
Mobile DNA, 2019 Transposable elements are endogenous DNA sequences able to integrate into and multiply within genomes. They constitute a major source of genetic innovations, as they can not only rearrange genomes but also spread ready-to-use regulatory sequences able to
Corentin Dechaud +3 more
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Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. [PDF]
PLoS ONE, 2011 H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila.
Zhenhai Zhang, B Franklin Pugh
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The biology and potential for genetic research of transposable elements in filamentous fungi
Genetics and Molecular Biology, 2005 Recently many transposable elements have been identified and characterized in filamentous fungi, especially in species of agricultural, biotechnological and medical interest.
Léia Cecilia de Lima Fávaro +3 more
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