Results 11 to 20 of about 93,119 (340)
Regulatory transposable elements in the encyclopedia of DNA elements
Nature Communications, 2023 Transposable elements (TEs) comprise ~50% of our genome, but knowledge of how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we provide the most comprehensive study to date of TE contributions to the regulatory genome.
Alan Y. Du +4 more
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Detection of DNA Methylation Changes Surrounding Transposable Elements
Bio-Protocol, 2013 Transposable elements (TEs) are a major component of all genomes, thus the epigenetic mechanisms controlling their activity is an important field of study.
Beery Yaakov, Khalil Kashkush
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Small RNAs, DNA methylation and transposable elements in wheat [PDF]
BMC Genomics, 2010 Background More than 80% of the wheat genome is composed of transposable elements (TEs). Since active TEs can move to different locations and potentially impose a significant mutational load, their expression is suppressed in the genome via small non ...
Matvienko Marta +7 more
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Proliferation of Regulatory DNA Elements Derived from Transposable Elements in the Maize Genome [PDF]
Plant Physiology, 2018 Genomic regions free of nucleosomes, which are hypersensitive to DNase I digestion, are known as DNase I hypersensitive sites (DHSs) and frequently contain cis-regulatory DNA elements. To investigate their prevalence and characteristics in maize (Zea mays), we developed high-resolution genome-wide DHS maps using a modified DNase-seq technique.
Hainan Zhao +6 more
openalex +3 more sources
DNA methylation enables transposable element-driven genome expansion [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance We examined recent whole-genome data of 53 organisms and found that the substantial differences in their genome sizes can be largely explained by the proportion of transposable elements (TEs) within them. TEs coexist with their host largely because CpG methylation suppresses their transcription.
Wanding Zhou +3 more
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Regulation of transposable elements by DNA modifications [PDF]
Nature Reviews Genetics, 2019 Maintenance of genome stability requires control over the expression of transposable elements (TEs), whose activity can have substantial deleterious effects on the host. Chemical modification of DNA is a commonly used strategy to achieve this, and it has long been argued that the emergence of 5-methylcytosine (5mC) in many species was driven by the ...
Özgen Deniz +2 more
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Comparative analysis of repeat content in plant genomes, large and small
Frontiers in Plant Science, 2023 The DNA Features pipeline is the analysis pipeline at EMBL-EBI that annotates repeat elements, including transposable elements. With Ensembl’s goal to stay at the cutting edge of genome annotation, we proved that this pipeline needed an update.
Joris Argentin +4 more
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Insertion sequence inversions mediated by ectopic recombination between terminal inverted repeats. [PDF]
PLoS ONE, 2010 Transposable elements are widely distributed and diverse in both eukaryotes and prokaryotes, as exemplified by DNA transposons. As a result, they represent a considerable source of genomic variation, for example through ectopic (i.e.
Alison Ling, Richard Cordaux
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Mobilization of DNA transposable elements from lentiviral vectors [PDF]
Mobile Genetic Elements, 2011 With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
Bak, Rasmus Otkjær +1 more
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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Nature Communications, 2020 Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates ...
Kevin H.-C. Wei +2 more
doaj +1 more source