Results 41 to 50 of about 4,232,910 (194)
A comparative investigation of nuclear DNA content and its phenotypic impacts in Silene marizii and S. latifolia [PDF]
, 2008 Considerable variation exists both within and between species in nuclear DNA content. Despite there being no obvious functional role for much of this DNA, many studies have reported phenotypic correlations with genome size at various taxonomic levels ...
Looseley, Mark E
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Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes
Nature Communications, 2023 Here the authors show transposable elements, formerly considered junk DNA, are a source of CTCF binding sites that contribute to species-specific 3D-genome structure, and may impact gene regulation during the course of mammalian evolution.
Mayank N. K. Choudhary +4 more
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Epigenetics & ChromatinDNA methylation is an essential epigenetic mechanism for regulation of gene expression, through which many physiological (X-chromosome inactivation, genetic imprinting, chromatin structure and miRNA regulation, genome defense, silencing of transposable ...
Alexandra Chera +3 more
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DNA methylation dynamics during early plant life
Genome Biology, 2017 Background Cytosine methylation is crucial for gene regulation and silencing of transposable elements in mammals and plants. While this epigenetic mark is extensively reprogrammed in the germline and early embryos of mammals, the extent to which DNA ...
Daniel Bouyer +6 more
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Bioinformatic analysis of Entamoeba histolytica SINE1 elements. [PDF]
, 2010 BACKGROUND: Invasive amoebiasis, caused by infection with the human parasite Entamoeba histolytica remains a major cause of morbidity and mortality in some less-developed countries. Genetically E.
Derek M Huntley +11 more
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Transposable Elements as a Source of Novel Repetitive DNA in the Eukaryote Genome
Cells, 2022 The impact of transposable elements (TEs) on the evolution of the eukaryote genome has been observed in a number of biological processes, such as the recruitment of the host’s gene expression network or the rearrangement of genome structure. However, TEs may also provide a substrate for the emergence of novel repetitive elements, which contribute to ...
Michelle Louise Zattera +1 more
openaire +3 more sources
Nature Communications, 2019 DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific —LINE-1 ...
Marie E Jönsson +12 more
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RIPCAL: a tool for alignment-based analysis of repeat-induced point mutations in fungal genomic sequences [PDF]
, 2008 Background Repeat-induced point mutation (RIP) is a fungal-specific genome defence mechanism that alters the sequences of repetitive DNA, thereby inactivating coding genes.
Hane, J. +7 more
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Proliferation of Regulatory DNA Elements Derived from Transposable Elements in the Maize Genome [PDF]
Plant Physiology, 2018 Genomic regions free of nucleosomes, which are hypersensitive to DNase I digestion, are known as DNase I hypersensitive sites (DHSs) and frequently contain cis-regulatory DNA elements. To investigate their prevalence and characteristics in maize (Zea mays), we developed high-resolution genome-wide DHS maps using a modified DNase-seq technique.
Hainan Zhao +6 more
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Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi. [PDF]
, 2007 BACKGROUND: Trypanosomes are parasitic protozoa that diverged early from the main eukaryotic lineage. Their genomes display several unusual characteristics and, despite completion of the trypanosome genome projects, the location of centromeric DNA has ...
Bot, Christopher +9 more
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