Identification and characterization of unique to human regulatory sequences in embryonic stem cells reveal associations with transposable elements, distal enhancers, non-coding RNA, and DNA methylation-driven mechanisms of genome editing [PDF]
Gennadi V. Glinsky
openalex +1 more source
Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng +8 more
wiley +1 more source
Haplotype-Resolved Chromatin Conformation Data Reveals Relationship Between Transposable Elements and Chromosomal Pairing. [PDF]
Genutis LK +5 more
europepmc +1 more source
Seasonality in temperate ecosystems shapes species phenology, influencing interactions and food web structure. Variations in species richness and biomass affect trophic interaction strength, a crucial factor for community stability, which can be assessed through energy fluxes – an essential indicator of ecosystem function.
Simon Bazin +4 more
wiley +1 more source
Anuran genome size evolution is driven by relatively recent retrotransposon activity and by life history. [PDF]
Rubio AO +6 more
europepmc +1 more source
Wasp communities associated with fig trees, Ficus spp., are a model system to investigate how local and regional processes shape biodiversity across large geographical ranges. We investigated the β‐diversity of fig wasp assemblages associated with three widely distributed Neotropical fig species – F. citrifolia, F. obtusifolia and F. pertusa – using 27
Elmecelli Moraes de Castro Souza +6 more
wiley +1 more source
The interplay of recombination landscape and a transposable element in European populations of Chironomus riparius. [PDF]
Pettrich LC, Waldvogel AM.
europepmc +1 more source
The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source

