Results 251 to 260 of about 167,159 (369)
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Genome of the green-head ant, Rhytidoponera metallica, reveals mechanisms of toxin evolution in a genetically hyper-diverse eusocial species. [PDF]
Isaksen A +6 more
europepmc +1 more source
Identification and characterization of unique to human regulatory sequences in embryonic stem cells reveal associations with transposable elements, distal enhancers, non-coding RNA, and DNA methylation-driven mechanisms of genome editing [PDF]
Gennadi V. Glinsky
openalex +1 more source
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood +6 more
wiley +1 more source
Long-read sequencing-based analyses of the adult Drosophila brain transcriptome in physiological and pathological settings. [PDF]
Ramirez P, Zuniga G, Ochoa E, Frost B.
europepmc +1 more source
Candida auris is an emerging multidrug‐resistant fungal pathogen that poses a serious global health threat. In our study, we comprehensively delineate both the pan‐genomic and transcriptomic features of C. auris. Intriguingly, our findings reveal an unexpected alkaline pH‐dependent regulation required for C. auris virulence and commensalism mediated by
Chaoyue Xu +30 more
wiley +1 more source
Probiotic Lactobacillus acidophilus strain LA01 was applied to bone powder fermentation. The adsorbable calcium, small peptides, and compounds with lipid‐lowering and antioxidant properties were greatly enriched. This study provided insights into the metabolism of probiotic fermentation and laid the scientific basis for development of value‐added ...
Ruijie Zhang +3 more
wiley +1 more source
Transposable element dynamics in glioblastoma stem cells: insights from locus-specific quantification. [PDF]
Pizzagalli MD +3 more
europepmc +1 more source

