Results 51 to 60 of about 3,025,811 (189)
Engineering DNA vaccines against infectious diseases
Acta Biomaterialia, 2018 Graphical ...
Jihui Lee +3 more
semanticscholar +1 more source
Toward QbD Process Understanding on DNA Vaccine Purification Using Design of Experiment
Frontiers in Bioengineering and Biotechnology, 2021 DNA vaccines, the third generation of vaccines, are a promising therapeutic option for many diseases as they offer the customization of their ability on protection and treatment with high stability.
Lalintip Hocharoen +2 more
doaj +1 more source
Molecular Adjuvants for DNA Vaccines.
Current Issues in Molecular Biology, 2017 Poor immunogenicity remains the single biggest obstacle to human DNA vaccines achieving their potential. Strategies to improve DNA vaccine efficacy include codon optimization, transfection reagents, electroporation, vaccine adjuvants or combination with ...
Lei Li, N. Petrovsky
semanticscholar +1 more source
DNA Vaccines: Regulatory Considerations and Safety Aspects.
Current Issues in Molecular Biology, 2017 DNA vaccines have great potential as preventive or therapeutic vaccines against viral, bacterial, or parasitic diseases as well as cancer, and may also be used as gene therapy products.
A. Myhr
semanticscholar +1 more source
Проблемы особо опасных инфекций, 2010 Cited are literary data related to the development of DNA vaccines against rabies virus. Research results regarding gene vaccination of different models of laboratory animals and different ways of vaccine introduction are presented.
I. V. Tuchkov, A. K. Nikiforov
doaj +1 more source
Comparison of DNA and mRNA vaccines against cancer.
Drug Discovery Today, 2019 Nucleic acid vaccines (NAVs) have recently been tested as a cancer therapy. DNA and mRNA vaccines deliver genetic information encoding tumor antigens (TAs) to the host, which then produces immune responses against cancer cells that express the TAs ...
Z. Jahanafrooz +6 more
semanticscholar +1 more source
Molecular Therapy: Methods & Clinical Development, 2020 DNA vaccines expressing codon-optimized Venezuelan equine encephalitis virus (VEEV) and Ebola virus (EBOV) glycoprotein genes provide protective immunity to mice and nonhuman primates when delivered by intramuscular (IM) electroporation (EP).
John J. Suschak +7 more
doaj +1 more source
Veterinární Medicína, 2023 Pseudomonas aeruginosa is an infectious pathogenic bacteria infecting many different species of animals. Currently, it lacks a commercial vaccine. In this study, three monovalent DNA vaccines (poprL, poprF, and pflgE), three bivalent combination DNA ...
Q Gong, Y Li, W Zhai, M Niu
doaj +1 more source
Next-Generation TB Vaccines: Progress, Challenges, and Prospects
Vaccines, 2023 Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global infectious disease and a leading cause of mortality worldwide. Currently, the only available vaccine for TB prevention is Bacillus Calmette–Guérin (BCG).
Zhuang Li +4 more
semanticscholar +1 more source
A Comparison of Plasmid DNA and mRNA as Vaccine Technologies
Vaccines, 2019 This review provides a comparison of the theoretical issues and experimental findings for plasmid DNA and mRNA vaccine technologies. While both have been under development since the 1990s, in recent years, significant excitement has turned to mRNA ...
Margaret A. Liu
doaj +1 more source