Bacterial Infections, DNA Virus Infections, and RNA Virus Infections Manifest Differently in Neutrophil Receptor Expression [PDF]
The Scientific World Journal, 2012 Treating viral illnesses or noninfective causes of inflammation with antibiotics is ineffective and contributes to the development of antibiotic resistance, toxicity, and allergic reactions, leading to increasing medical costs.
Esa-Matti Lilius, Jari Nuutila
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Interplay between Lipid Metabolism, Lipid Droplets, and DNA Virus Infections [PDF]
Cells, 2022 Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and cholesterol esters that are coated by a phospholipid monolayer and associated proteins. LDs are known to play important roles in the storage and availability of
Mónica A. Farías +4 more
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Human papilloma and other DNA virus infections of the cervix: A population based comparative study among tribal and general population in India. [PDF]
PLoS ONE, 2019 BackgroundDespite being preventable, cervical cancer remains a major health concern among women. Persistent Human Papillomavirus (HPV) and other viral co-infections may influence cervical dysplasia.
Supriti Ghosh +9 more
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TRIM29 promotes DNA virus infections by inhibiting innate immune response [PDF]
Nature Communications, 2017 Proteins of the TRIM family have regulatory functions in immune signaling, often via ubiquitination of target proteins. Here, the authors show that TRIM29 is induced upon infection with DNA viruses, resulting in degradation of STING, decreased interferon
Junji Xing +6 more
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Hepatitis B Virus DNA Integration, Chronic Infections and Hepatocellular Carcinoma [PDF]
Microorganisms, 2021 Hepatitis B Virus (HBV) is an Old World virus with a high mutation rate, which puts its origins in Africa alongside the origins of Homo sapiens, and is a member of the Hepadnaviridae family that is characterized by a unique viral replication cycle.
Maria Bousali +3 more
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Nuclear Soluble cGAS Senses DNA Virus Infection [PDF]
SSRN Electronic Journal, 2021 ABSTRACTThe cytosolic DNA sensor cGAS detects foreign DNA from pathogens or self-DNA from cellular damage and instigates type I interferon (IFN) expression. Recent studies find that cGAS also localizes in the nucleus and binds the chromatin. Despite how cGAS is inhibited in the nucleus is well elucidated, whether nuclear cGAS participates in DNA ...
Yakun Wu +4 more
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Kidney Transplant-Associated Viral Infection Rates and Outcomes in a Single-Centre Cohort
Viruses, 2022 Background: Opportunistic infections remain a significant cause of morbidity and mortality after kidney transplantation. This retrospective cohort study aimed to assess the incidence and predictors of post-transplant DNA virus infections (CMV, EBV, BKV ...
Kairi Pullerits +7 more
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From infection to cancer: how DNA tumour viruses alter host cell central carbon and lipid metabolism [PDF]
Open Biology, 2021 Infections cause 13% of all cancers globally, and DNA tumour viruses account for almost 60% of these cancers. All viruses are obligate intracellular parasites and hijack host cell functions to replicate and complete their life cycles to produce progeny ...
Kamini L. Magon, Joanna L. Parish
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Evaluating vertical transmission of sexually transmitted infections to newborns
Journal of Infection in Developing Countries, 2021 Introduction: Sexually transmitted infections are among the most frequent infections affecting pregnant women. We assessed the transmission of hepatitis B virus, human immunodeficiency virus type 1 and Treponema pallidum to newborns from infected ...
Dinamene Oliveira +5 more
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Vaccines against persistent DNA virus infections [PDF]
British Medical Bulletin, 2002 Persistent viruses present some particular problems for vaccine design. As for acute non-persistent viruses, the prime goal of a vaccine should be to prevent primary infection. Vaccines might also be used to modify the course of established persistent virus infections - so-called postinfective immunisation.
M R, Wills +2 more
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