The main DNA viruses significantly affecting pig livestock
Swine DNA viruses have developed unique mechanisms for evasion of the host immune system, infection and DNA replication, and finally, construction and release of new viral particles.
Díaz Carlos +2 more
doaj +1 more source
Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization
Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells ...
Haruhiko Murata +7 more
doaj +1 more source
Contribution of hypoxia inducible factor-1 during viral infections
Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that plays critical roles during the cellular response to hypoxia. Under normoxic conditions, its function is tightly regulated by the degradation of its alpha subunit (HIF-1α), which impairs ...
Antonia Reyes +5 more
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The early discoveries of Gross (1951) of viral causation of murine leukemias, the subsequent demonstration of retroviruses as the causative factors and the presence of similar viruses particularly in lymphoproliferative disorders in cattle, cats, and various rodent species, underlined for decades the justi®cation of attempts to search for similar ...
openaire +2 more sources
Systematic CpT (ApG) depletion and CpG excess are unique genomic signatures of large DNA viruses infecting invertebrates. [PDF]
Differences in the relative abundance of dinucleotides, if any may provide important clues on host-driven evolution of viruses. We studied dinucleotide frequencies of large DNA viruses infecting vertebrates (n = 105; viruses infecting mammals = 99 ...
Mohita Upadhyay +2 more
doaj +1 more source
First Report on Detection and Complete Genomic Analysis of a Novel CRESS DNA Virus from Sea Turtles
To date, only a handful of viruses have been identified in sea turtles. Although eukaryotic circular Rep (replication initiation protein)-encoding single-stranded DNA (CRESS DNA) viruses have been reported from a wide variety of terrestrial species, and ...
Kerry Gainor +8 more
doaj +1 more source
Pepper yellow leaf curl Indonesia virus, a new bipartite begomovirus species that belongs to distinct clade of Old World geminiviruses [PDF]
Begomoviruses are currently emerging as a major threat to vegetable production in many tropical and subtropical regions worldwide. Pepper yellow leaf curl disease (PepYLCD) has been noticed in many Capsicum annum L.
J. Sakata2 +3 more
core +2 more sources
Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex
BRCA1 is a tumor suppressor found to be mutated in hereditary breast and ovarian cancer and plays key roles in the maintenance of genomic stability by homologous recombination repair.
Otto J.P. Kyrieleis +9 more
doaj +1 more source
Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruption. [PDF]
Combination antiretroviral therapy controls but does not cure HIV-1 infection because a small fraction of cells harbor latent viruses that can produce rebound viremia when therapy is interrupted. The circulating latent virus reservoir has been documented
Barton, John +13 more
core +1 more source
Human Herpesvirus Sequencing in the Genomic Era: The Growing Ranks of the Herpetic Legion
The nine human herpesviruses are some of the most ubiquitous pathogens worldwide, causing life-long latent infection in a variety of different tissues. Human herpesviruses range from mild childhood infections to known tumour viruses and ‘trolls of ...
Charlotte J. Houldcroft
doaj +1 more source

