Results 21 to 30 of about 367,032 (262)

A chemical method for generating live-attenuated, replication-defective DNA viruses for vaccine development

open access: yesCell Reports: Methods, 2022
Summary: The development of a chemically attenuated, replication-incompetent virus vaccine can provide protection against diseases caused by DNA viruses.
Dabbu Kumar Jaijyan   +3 more
doaj   +1 more source

Gestational Viral Infections: Role of Host Immune System

open access: yesMicroorganisms, 2023
Viral infections in pregnancy are major causes of maternal and fetal morbidity and mortality. Infections can develop in the neonate transplacentally, perinatally, or postnatally (from breast milk or other sources) and lead to different clinical ...
Silvia Beltrami   +6 more
doaj   +1 more source

Diversity of CRESS DNA Viruses in Squamates Recapitulates Hosts Dietary and Environmental Sources of Exposure

open access: yesMicrobiology Spectrum, 2022
Replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses comprise viruses with covalently closed, circular, single-stranded DNA (ssDNA) genomes, and are considered the smallest known autonomously replicating, capsid-encoding ...
Paolo Capozza   +14 more
doaj   +1 more source

Universal Virucidal Activity of Calcium Bicarbonate Mesoscopic Crystals That Provides an Effective and Biosafe Disinfectant

open access: yesMicroorganisms, 2022
We investigated the virucidal effects in solution of a new type of disinfectant, calcium bicarbonate mesoscopic crystals, designated CAC-717, against various types of virus.
Rikio Kirisawa   +3 more
doaj   +1 more source

Novel circular single-stranded DNA viruses identified in marine invertebrates reveal high sequence diversity and consistent predicted intrinsic disorder patterns within putative structural proteins

open access: yesFrontiers in Microbiology, 2015
Viral metagenomics has recently revealed the ubiquitous and diverse nature of single-stranded DNA (ssDNA) viruses that encode a conserved replication initiator protein (Rep) in the marine environment.
Karyna eRosario   +4 more
doaj   +1 more source

Modern taxonomy of viruses of vertebrates

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2020
The modern taxonomy of viruses of vertebrates is presented according to the information of ICTV issue 07.2019, ratification 03.2020. The leading criteria of taxonomy of viruses are named: type and structure of viral genome, mechanism of replication and ...
O. S. Kalinina
doaj   +1 more source

CXCL10 Chemokine: A Critical Player in RNA and DNA Viral Infections

open access: yesViruses, 2022
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration and contribute to their activation. Chemokines are crucial inflammatory mediators that play a key role in managing viral infections, during which the profile of ...
Noha Mousaad Elemam   +2 more
doaj   +1 more source

Deciphering the Origin of DNA Viruses (Replication-Associated Parvo-NS1) That Infect Vertebrates from Invertebrate-Infecting Viruses

open access: yesMicrobiology Spectrum, 2023
DNA replication is a standard and essential function among DNA viruses; however, this functional domain's common ancestor, origin, and evolutionary path in invertebrate- and vertebrate-infecting viruses are not yet fully understood.
Perumal Arumugam Desingu   +2 more
doaj   +1 more source

Pervasive Chimerism in the Replication-Associated Proteins of Uncultured Single-Stranded DNA Viruses

open access: yesViruses, 2018
Numerous metagenomic studies have uncovered a remarkable diversity of circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses, the majority of which are uncultured and unclassified. Unlike capsid proteins, the Reps show
Darius Kazlauskas   +2 more
doaj   +1 more source

Inhibition of histone methyltransferase SETD8 represses DNA virus replication

open access: yesCell Insight, 2022
Multiple diseases, such as cancer and neural degeneration diseases, are related with the latent infection of DNA viruses. However, it is still difficult to clean up the latent DNA viruses and new anti-viral strategies are critical for disease treatment ...
Lin Chen   +6 more
doaj   +1 more source

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