Results 61 to 70 of about 614,581 (300)

Interplay between the DNA damage response and the life cycle of DNA tumor viruses

open access: yesTumour Virus Research, 2023
Approximately 20 % of human cancers are associated with virus infection. DNA tumor viruses can induce tumor formation in host cells by disrupting the cell's DNA replication and repair mechanisms. Specifically, these viruses interfere with the host cell's
Caleb J. Studstill   +2 more
doaj   +1 more source

Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Suppresses Transcriptional Gene Silencing [PDF]

open access: yes, 2015
Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit. The replication of the largest known family of single-stranded DNA viruses, Geminiviridae, is impaired by DNA methylation but the fact ...
Cruzado, Lucia   +5 more
core   +1 more source

Characterization of DNA methylation as a function of biological complexity via dinucleotide inter-distances

open access: yes, 2015
We perform a statistical study of the distances between successive occurrencies of a given dinucleotide in the DNA sequence for a number of organisms of different complexity.
Castellani, Gastone C.   +6 more
core   +1 more source

Force steps during viral DNA packaging ? [PDF]

open access: yes, 2003
Biophysicists and structural biologists increasingly acknowledge the role played by the mechanical properties of macromolecules as a critical element in many biological processes.
Alberts   +29 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

DNA plant viruses

open access: yesCalifornia Agriculture, 1982
Not available – first paragraph follows: A remarkably simple genetic system for study of DNA multiplication and gene expression in plants is provided by DNA plant viruses.
R Shepherd, S Daubert, R Gardner
doaj  

Towards quantitative viromics for both double-stranded and single-stranded DNA viruses [PDF]

open access: yesPeerJ, 2016
Background Viruses strongly influence microbial population dynamics and ecosystem functions. However, our ability to quantitatively evaluate those viral impacts is limited to the few cultivated viruses and double-stranded DNA (dsDNA) viral genomes ...
Simon Roux   +8 more
doaj   +2 more sources

Cancer is a side effect of evolution of viruses and bacteria [PDF]

open access: yes, 2011
Any human organism is home to viruses and bacteria. However, viruses (as well as other intracellular parasites) are interested in continuous division of the host cells.
Valentin Mitin
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Unveiling CRESS DNA Virus Diversity in Oysters by Virome

open access: yesViruses
Oysters that filter feed can accumulate numerous pathogens, including viruses, which can serve as a valuable viral repository. As oyster farming becomes more prevalent, concerns are mounting about diseases that can harm both cultivated and wild oysters ...
Peng Zhu   +8 more
doaj   +1 more source

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