Results 171 to 180 of about 94,936 (269)

Laryngeal NUT Carcinoma With BRD4::NUTM1 Fusion: A 4‐Year Clinical Course Highlighting the Limitations of Current Multimodal Therapy

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Nuclear protein in testis (NUT) carcinoma is a rare, aggressive malignancy driven by NUTM1 rearrangement, often misdiagnosed as squamous cell carcinoma, with no established standard therapy. This report describes the clinical course and treatment resistance in primary laryngeal NUT carcinoma and provides insights into potential ...
Masafumi Kanno   +15 more
wiley   +1 more source

Cancer-Control Outcomes of Japanese Vs. German Metastatic Hormone-Sensitive Prostate Cancer Patients: A Real-World Cross-Country Comparison of Patients Undergoing Combination Therapies. [PDF]

open access: yesInt J Urol
ABSTRACT Objectives Differences in tumor biology, ethnicities, and healthcare structures across populations may contribute to variability in oncologic outcomes. This study compared baseline characteristics and oncologic outcomes of Japanese and German metastatic hormone‐sensitive prostate cancer (mHSPC) patients.
Wenzel M   +13 more
europepmc   +2 more sources

Fewer Injections and Lower Drug Costs With Long‐Acting GnRH Depot Formulations: A Nationwide Analysis of 2.3 Million Patient‐Years in Japan

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Androgen deprivation therapy (ADT) is the base of treatment for prostate cancer, and gonadotropin‐releasing hormone (GnRH) drugs are given as depot injections. Long‐acting formulations may reduce the number of injections and the drug cost, but this impact has not been quantified in real practice.
Takashi Kawahara   +7 more
wiley   +1 more source

Lactoferrin and Nanotechnology: New Insights Into Glioblastoma Therapy

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Current glioblastoma multiforme (GBM) management primarily relies on surgery, chemotherapy, and radiotherapy; however, therapeutic efficacy remains limited due to tumor invasiveness and restricted drug penetration across the blood–brain barrier. Lactoferrin (LF), an iron‐binding glycoprotein with receptor‐mediated transport capability, has emerged as a
Atena Abed, Javad Amini Mahabadi
wiley   +1 more source

Gemcitabine-Based Bladder Preservation in BCG-Unresponsive High-Risk NMIBC: Evidence, Limitations, and Clinical Positioning. [PDF]

open access: yesBiomedicines
Kaltsas A   +9 more
europepmc   +1 more source

Bevacizumab plus nab‐paclitaxel and platinum as second‐line therapy for driver‐gene‐negative non‐squamous non‐small cell lung cancer after immunochemotherapy: A prospective single‐arm single‐centre study

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
This study prospectively evaluated the efficacy and safety of the bevacizumab, nab‐paclitaxel and platinum combination as a second‐line therapy for driver‐gene‐negative advanced non‐squamous non‐small cell lung cancer after immunochemotherapy. The confirmed objective response rate was 46.4%.
Ying Lin   +12 more
wiley   +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

open access: yesHead &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan   +12 more
wiley   +1 more source

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