Results 151 to 160 of about 89,572 (287)
International Statistical Review, EarlyView.Summary In high‐dimensional survival analysis, effective variable selection is crucial both for model interpretation and predictive performance. This paper investigates Cox regression with lasso and adaptive lasso penalties in genomic datasets where covariates far outnumber observations.
Pilar González‐Barquero +2 more
wiley +1 more source
, 2015 George Dranitsaris,1 Bo Yu,2 Jennifer King,3 Satyin Kaura,3 Adams Zhang3 1Augmentium Pharma Consulting Inc., Toronto, ON, Canada; 2Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China; 3Celgene Corporation, Summit, NJ, USA ...
Yu B +4 more
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Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Head and neck squamous cell carcinoma is a heterogeneous disease with poor survival outcomes. Bcl‐xL regulates tumor cell survival and apoptosis and has been associated with metastasis and poor prognosis, although its overall role remains undeciphered.
L. Leinonen +6 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model
Photochemistry and Photobiology, EarlyView.Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore +6 more
wiley +1 more source
Retrospective Study of Weekly Docetaxel (Taxotere) in Previously Treated Non-Small Cell Lung Cancer
, 2007 肺癌為最常見之惡性疾病之一，亦為惡性腫瘤中死亡率最高者之一，在國人癌症死因中高居第二位。自從發現含鉑化學治療對於非小細胞肺癌有益，在嚴重非小細胞肺癌病患中，化學治療的使用也日益廣泛，也使得需要後線化療之病患日漸增加。 Docetaxel為一紫杉醇類似物，對於非小細胞肺癌單獨使用亦有活性，為美國藥物食品管理局第一個核准使用於非小細胞肺癌第二線化學治療的藥物。然而，傳統的docetaxel 給藥方式，常造成釵h嚴重的急性副作用；一些小型的研究發現，若以低劑量每週給藥，可減低急性毒性 ...
羅英, Lo, Yin
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Authors' Reply to Letter to the Editor: Sequential Ramucirumab Plus Docetaxel After PD‐1 Inhibitors
Cancer Science, EarlyView.
Kinnosuke Matsumoto +2 more
wiley +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma +6 more
wiley +1 more source
Excessive Tearing and Lacrimal and Canalicular Blockage Secondary to Docetaxel in Breast Cancer Patients in the Metastatic and Adjuvant Settings. [PDF]
Curr OncolPfeiffer ML, Esmaeli B.
europepmc +1 more source
Development of docetaxel nanocrystals surface modified with transferrin for tumor targeting
, 2016 Jin-Seok Choi, Jeong-Sook Park College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Yuseong-gu, Daejeon, South Korea Abstract: The purpose of this study was to develop the surface modification of docetaxel ...
Choi JS, Park JS
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