Results 21 to 30 of about 89,572 (287)
The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment
Cell & Bioscience, 2023 Background Prostate cancer is a leading cause of cancer-related deaths among men worldwide. Docetaxel chemotherapy has proven effective in improving overall survival in patients with castration-resistant prostate cancer (CRPC), but drug resistance ...Bisheng Cheng, Lingfeng Li, Yongxin Wu, Tianlong Luo, Chen Tang, Qiong Wang, Qianghua Zhou, Jilin Wu, Yiming Lai, Dingjun Zhu, Tao Du, Hai Huang +11 moredoaj +1 more sourceNanocrystal-Loaded Micelles for the Enhanced In Vivo Circulation of Docetaxel
Molecules, 2021 Prolonging in vivo circulation has proved to be an efficient route for enhancing the therapeutic effect of rapidly metabolized drugs. In this study, we aimed to construct a nanocrystal-loaded micelles delivery system to enhance the blood circulation of ...Meng Cheng, Qiaoming Liu, Tiantian Gan, Yuanying Fang, Pengfei Yue, Yongbing Sun, Yi Jin, Jianfang Feng, Liangxing Tu +8 moredoaj +1 more sourceHigh efficacy and low toxicity of weekly docetaxel given as first-line treatment for metastatic breast cancer [PDF]
, 2005 Background: Docetaxel is one of the most effective antitumor agents currently available for the treatment of metastatic breast cancer (MBC). This phase II multicenter study prospectively analyzed the efficacy and toxicity of docetaxel given on a weekly ...Abenhardt, Wolfgang, Leinung, S., V. Heinemann, Stemmler, J., W. Mair, Jackisch, C., O. Brudler, G. Deutsch, Stamp, J., Dorn, B., J. Stemmler, Brudler, O., Stauch, M., M. Malekmohammadi, Papke, J., M. Stauch, Deutsch, G., Vehling-Kaiser, U., S. Leinung, B. Dorn, Heinemann, Volker, C. Jackisch, U. Vehling-Kaiser, Mair, W., Kentenich, C., J. Papke, C. Kentenich, Malekmohammadi, M., W. Abenhardt, J. Stamp +29 morecore +1 more sourceProspective Multicenter Randomized Phase III Study of Weekly versus Standard Docetaxel (D2) for First-Line Treatment of Metastatic Breast Cancer [PDF]
, 2010 Purpose: Previous phase II studies have indicated a greatly reduced hematotoxicity of docetaxel-based regimens administered on weekly schedules. The present trial was initiated to randomly compare the toxicity and efficacy of weekly docetaxel versus its ...Abenhardt, Wolfgang, Rauthe, Gerhard, Marion Kiechle, Stemmler, Hans-Joachim, Heinemann, Volker, Harald Sommer, Artmann, Almut, Sommer, Harald, Isolde Gröll de Rivera, Hans-Gerd Meerpohl, de Rivera, Isolde Groell, Meerpohl, Hans-Gerd, Nadia Harbeck, Gerhard Rauthe, Harbeck, Nadia, Volker Heinemann, Kiechle, Marion, Kaiser, Ursula Vehling, Ursula Vehling Kaiser, Wolfgang Abenhardt, Almut Artmann, Hans-Joachim Stemmler +21 morecore +1 more sourceDocetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02) : an open-label, phase 3 randomised controlled trial [PDF]
, 2008 Background:
Second-line chemotherapy for patients with oesophagogastric adenocarcinoma refractory to platinum and fluoropyrimidines has not shown benefits in health-related quality of life (HRQoL). We assessed whether the addition of docetaxel to active Cliona C Kirwan (10530920), Burnett, Alan K., Carmichael, Amtul, Neal, Richard D, Mallon, Elizabeth, Greenhalf, W, Faria, Claudia C., Wen, Patrick Y, Zimmermann, C., Murray, G, Hickish, T, Dommett, R., Berendsen, A, Wen, Patrick Y., Fareeda Coxon, Greenhalf, William, Xu, B, Torchia, Jonathon, Patricia Fairbrother (10530899), Harvey, J, Evans, A, de Wit, Niek, Janowitz, T., Dunkel, Ira J, Martin, Paul, Waters, Justin S., Cherian, Meena Nathan, Skene, Anthony, Roques, Tom, Camilla Zimmermann, Wildiers, Hans, Benson, JR, A Goyal (7752236), O'Donovan, Anita, Ching Ho, King, Grech, Angela, Voruganti, Teja, Bridgewater, J. A., Wilkinson, Clare, Kefford, Richard, Whitlock, J., Eatock, M, Wataya, Takafumi, Holcombe, Chris, Vezina, Gilber, Trimboli, R.M., Walker, J, Wardle, Jane, Barakzai, Muhammad Abrar, Morden, James, S Michael Crawford, Bouffet, Prof Eric, Evans, J, Horgan, K, Falk, S., Madhusudan, S., Watson, E., Johnson, Miriam J., Benson, John R, J. S. Waters (7644221), Ford, Hugo E R, Palmer, DH, Kilburn, L, McIntosh, SA, Jones, Gail, Neoptolemos, JP, CC Kirwan (7752239), Hiom, S, Reeve, B.B., Colver, Graham B, Franceschi, Enrico, Wender, R, Chan, Jennifer A, Rueda, Oscar M., Poussaint, Tina Y., K. Morris (7644206), Peake, M, Kim, Seung-Ki, Sisler, J, SMaRT (Symptom Management Research Trials) Oncology-3 Team, D. Cunningham (2534575), Hauser, Peter, Stephen Taplin, Friis, Lone, Caldas, C, Horgan, Kieran, Sussman, J, Kyte, Derek, Taplin, Stephen, Hiom, S., Hills, Robert K, Ross, Paul J., Charlotte Rawcliffe, Macleod, U., Van Meter, Timothy E., Karnakis, Theodora, Soto-Perez-de-Celis, E., Emery, Jon, Cunningham, D., Strother, Douglas, RI Cutress (7705409), Mitchell, Geoffrey, Cox, T, Cox, Trevor, Archer, Caroline, Anthoney, DA, Raghavan Vidya (10530911), Evans, Anthony G., Glas, N.A. de, Warren, Katherine E, Nicolson, Marianne, Evans, Anthony, Hongeng, Suradej, MacDonald, Tobey J, Currow, DC, Ellis, Ian O., Rees, Robert C., Anthony Evans, Schueller, Ulrich, Morgan, Yvonne G, Hunter, Ann, Greenhalf, W., Wadd, N., Hukin, Juliette, Burnett, Alan K, Hawkins, Cynthia E, Mason, R., Moseley, PM, Harrison, M, Kirwan, C, Benn, K., Hortobágyi, Tibor, Cutress, Ramsey I, Aapro, MS, William Greenhalf, Bridgewater, JA, Ball, Graham R., Taplin, S., Aapro, Matti S., Abdel-Fatah, TMA, Kirkwood, John M., Lorigan, Paul; id_orcid, Wardle, J., Peter Vedsted, S. Madhusudan (6554321), Kenis, Cindy, Wadsley, J, Benn, Karen, Chan, Stephen Y.T., Wadd, N, Agarwal, D, Grassi, L., Eva Grunfeld, Cook, Natalie; id_orcid, Nanson, Gemma, McAdam, Karen, Judkins, Alexander R., Georgios Lyratzopoulos, Propper, D., Phillips, Joanna, A. Lopes (7644197), Bogn�r, Laszl�, Haworth, Kellie B, Kilburn, Lucy, Ramsey I. Cutress (12375363), Sharpe, Michael, Dodson, Andrew, Cunningham, D., Marshall, Andrea, Ho, King Ching, Eatock, Martin, Musolino, Najia, Cheung, Kwok-Leung, Zimmermann, C, Ford, H. E., Blazeby, Jane M, Bognár, Laszló, Liu, DX, Valle, J, Roque, Lucia, Lee, Sandra J., Campbell, Fiona, Lyratzopoulos, Georgios, JS Vaidya (7752254), Devi, Beena, Crawford, M., Gourley, C, Cunningham, David, Richard Wender, Dodson, A, Johnston, Donna, Wadd, Nick, Costello, E, Ponti, A., Neal, Richard D., Gupta, S, Rawcliffe, Charlotte L., Srinivasan Madhusudan, Evans, Abigail, Cardoso, Maria-Joao, Van Meter, Timothy E, Hills, Robert K., Wasan, H., Dive, C, Wender, R., Palmer, Daniel H, Abernethy, Amy P, Mason, R, Extermann, Martine, Dive, Caroline, Neoptolemos, John, Lyratzopoulos, G, Harvey, James, Hunter, D., Fangusaro, Jason R., Lafay-Cousin, Lucie, Ross, P., Calvert, Melanie, Abernethy, AP, Fangusaro, Jason R, Scheineman, Prof Katrin, Ozolins, Mara, Anthoney, Alan, Armstrong, Sarah J., Palmer, Daniel H., Ross, PJ, Jabado, Nada, Marshall, A. (Andrea), Costello, Eithne, S Potter (7655408), Propper, D, Mata-Mbemba, Daddy, Association Of Breast Surgery Surgical Gap Analysis Working Group, Sisler, J., Sussman, Jonathan, Evans, Jeff, Niek de Wit, Jeremy Whelan, James Harvey (6581414), Colver, Graham B., Korc-Grodzicki, B, Sibbering, M, Haworth, Kellie B., Korc-Grodzicki, B., Kaur, Geetinder, Zimmerman, C, Wall, Lucy, Pippa Corrie, Hunter, D.J., Cheang, M, Amit Goyal (2678353), Corrie, Pippa, Earle, Craig, Grunfeld, E, Michael Peake, Perkins, William, Emery, J., de Glas, Nienke Aafke, Peake, Michael, Will P. Steward (7644224), Robertson, John, Shaw, Victoria, Chan, SYT, Middleton, G., Tamrazi, Benita, Lowis, Stephen, Macleod, U, Judkins, Alexander R, Cox, T., Long, Georgina V, Ball, GR, Ng, Ho-keung, Walker, Jane, Beare, S, Foreman, Prof Nick, Hiom, Sara, on behalf of Association for Palliative Medicine for Great Britain and Ireland, Trevor Cox, JR Benson (7752260), Kaur, G., Biganzoli, L., Hunter, D, Russell, R, Hamilton, W, P. J. Ross (7644218), Vezina, Gilbert, Silcocks, P, Ra, Prof Young-Shin, Peake, M., Pimentel, Jos�, Brain, EGC, Nicolaides, Theodore, Association of Breast Surgery Surgical Gap Analysis Working Group (7752266), Naisbitt, Dean, John P Neoptolemos, Blazeby, J. M., Una Macleod, Neoptolemos, J.P., Russell, Nigel H, Middleton, G, Xu, Bing, Grimwade, David, Waters, JS, Smith, Ian, Fearon, Kenneth C, Crawford, SM, Cardoso, M.J., Zielenska, Maria, Sin-Chan, Patrick, Mitchell, G., Middleton, Gary W., Voruganti, T, Cardoso, Maria João, de Glas, Nienke, Steward, WP, Dowsett, Mitch, Gupta, S., AR Carmichael (7752248), SA McIntosh (7752233), Amtul R. Carmichael (16671834), Backen, Alison C., Wasan, Harpreet, Ross, R. Paul, Warmuth-Metz, Prof Monika, Iveson, Tim, Whelan, J, Bowen, David, Jeff Sisler, Symeonides, Stefan, Hortob�gyi, Tibor, Ross, Paul J, Chan, Tiffany Sin Yu, Dunn, J. A., Zimmermann, Camilla, Seifert, B, Bliss, Judith M, Reed, Malcolm WR, Carret, Anne-Sophie, Campbell, F., Eisenstat, David D., Kirwan, Cliona C., Cheang, Maggie, Cook, Natalie, Shelley, Mike D., Tihan, Tarik, Roland, M., Shaw, Victoria E, Coxon, Fareeda Y., Symeonides, S, Ross, P, Pockley, AG, Macleod, Una, Baskin, Berivan, Wender, Richard, Garcia-Alonso, A, de Wit, N, Patel, Poulam M, Coxon, Fareeda Y, Warren, Katherine E., Backen, AC, Voruganti, T., Ascierto, Paolo A., Lyratzopoulos, G., Morden, J, Ascierto, Paolo A, McMullin, Mary Frances, Clark, Richard E, Flaherty, Keith T., McIntosh, Stuart A., Steward, W, Russell, Roslin, Goyal, Amit, Kunkler, I.H., Fahey, T, Anthoney, D Alan, Vaidya, Jayant S., Vidya, Raghaven, R Vidya (7752251), Tsang, Janice, Richard D Neal, Banerji, J, Smith, I, Grunfeld, E., Valle, J.W., Williams, Susan M., Jonathan Wadsley, Eisenstat, David D, Basch, Ethan, Ra, Young-Shin, Carmichael, Amtul R., Mitchell, G, Maclead, U, Whitlock, James, Benson, John R., John R Benson (16266674), Schüller, Ulrich, Duus, Elizabeth M, Wilcox, M, Stuart A. McIntosh (5693006), J Harvey (7752242), Lok, Jennie, Sisler, Jeff, Nakamura, Hideo, Sara Hiom, Anthoney, A, Neoptolemos, John P, Jon Emery, Pimentel, José, Marotti, L, Berendsen, A., Klekner, Almos, Maraveyas, Anthony, Jayant S. Vaidya (14979294), Bliss, JM, Weller, D., Duus, EM, Biganzoli, Laura, Rubin, G., Middleton, Gary, Malcolm Reed (4465876), Martin, P, Rachel Dommett, Fryer, Chris, Emery, J, Steward, William, D. A. Anthoney (7644212), Srinivasan, Narayanan, Cunningham, D, Amtul R Carmichael (16266668), Crawford, S. Michael, Vidya, Raghavan, David Weller, Albrecht, Steffen, Mansoor, W., Kirwan, Cliona, Teja Voruganti, Friend, J, Roland, M, Banerji, Jane, Iveson, T, Gary Middleton, Dirks, Peter, Soto-Perez-de-Celis, E, Grundy, Richard G., Mueller, Sabine, Sch�ller, Ulrich, Birks, Diane, Fearon, KC, Francis, A, Coxon, Fareeda, Fairbrother, Patricia, Maraveyas, A, Marotti, Lorenza, Mason, Robert, Ford, Hugo, Cook, N., Dommett, Rachel, Nicolson, M, Luigi Grassi, Whelan, Jeremy, Potter, S, Hansen, CH, Rutka, James T., McIntosh, Stuart, Dowsett, M, Garami, Miklos, Beare, Sandy, Poussaint, Tina Y, Seifert, Bohumil, Hickish, Tamas, Miller, Paul S J, Lulla, Rishi R, Falk, S., Yan, Y, Goyal, A, Coles, Bernadette, de Glas, NA, Jackson, R., Cutress, Ramsey, Sidhu, K, Montpetit, Alexandre, Sumit Gupta, Hamilton, Willie, Craig Earle, Cardoso, M-J, Earle, C, Sharpe, M, Propper, David, Schadendorf, Dirk, Ross, Paul, Caldas, Carlos, Fryer FRCPC, Chris, Cliona C. Kirwan (3934682), Annette Berendsen, Wilcox, Maggie, Rawcliffe, C., Kunkler, IH, Liu, K, Letourneau, Louis, Gupta, Sumit, Moseley, Paul M., C. Rees (7644227), Brain, Etienne G.C., Colloca, Giuseppe, Wilkinson, CE, Rutkowski, Stefan, Weller, David, Valle, Juan W, Green, AR, Huang, Dr Annie, Morgan, Paul S, Neoptolemos, J, Silcocks, Paul, Michaud, Jean, J. W. Valle (7644191), Morgan, Paul S., Rees, C, Janowitz, Tobias, M. Duggan (7644209), Walter, Fiona, Anthoney, D. Alan, David Propper, Shaw, VE, Warmuth-Metz, Monika, Noble, Simon IR, Larbcharoensub, Noppadol, Rawcliffe, Charlotte, A Francis (7752245), Abrar Barakzai, Muhammad, Garcia-Alonso, Angel, Soto-Perez-de-Celis, Enrique, Hennig, Michael, Grundy, Richard, Dunham, Christopher P, Marshall, A., Evans, A., Benn, K, Murray, Gordon, Wilkinson, C., Richard Jackson, Juan W Valle, Trimboli, Rubina M., Reed, Malcolm W.R., David Hunter, Daniel H Palmer, Eila Watson, Robertson, J, Holcombe, C, Reed, Malcolm, Waters, Justin S, Duggan, Marian, Douek, M, Sin Yu Chan, Tiffany, Shaw, Victoria E., Fahey, T., Cutress, RI, Neal, RD, Fiona Campbell, Falk, S, Sussman, J., Grassi, Luigi, Pietsch, Torsten, Ghaneh, Paula, Brain, Etienne, Wildiers, H., Archer, C, Lu, Jian-Qiang, Neal, R., Hammond, Robert, Carmichael, Amtul R, Williams, Hywel C, Whitlock, J, MacDonald, Tobey J., English, Martin, Wildiers, H, Wilkinson, C, Costello, E., Jackson, R, Vaidya, Jayant S, Berendsen, Annette, Hauschild, Axel, Fults, Daniel, Lopes, A, Battisti, Nicole Matteo Luca, Duggan, M, Agarwal, Devika, Victoria E Shaw, Madhusudan, Srinivasan, Swinson, D., Aapro, M.S., Armstrong, Sarah J, P Fairbrother (7752257), Foreman, Nick, Lorigan, Paul, C. Dive (7594496), Kareclas, Paula, Yip, Stephen, Vidya, R, Tsang, J, Prados, Michael D, Ponti, A, H. Wasan (7644194), Hansen, Christian Holm, Nanson, G, Chau, I., Bath-Hextall, Fiona, Williams, Hywel C., A. C. Backen (7644200), Robert Mason, Grundy, Richard G, Dummer, Reinhard, Dunn, Janet A., Shelley Potter (3405653), Rutka, James T, Shaw, V, Kunkler, Ian H., Dunham, Christopher P., Falk, Stephen, Coxon, F. Y., Steer, Christopher, COUGAR-02 Investigators, Rutkowski, Prof Stefan, Jane Wardle, Brandes, Alba A, Somers, Gino R, Peet, Andrew, Grassi, L, Dunkel, Ira J., Dommett, R, Corrie, P, Ponti, Antonio, Hamaker, Marije, Crawford, S Michael, Mallon, E, Scheineman, Katrin, Whelan, J., Brandes, Alba A., Zelcer, Shayna, Bouffet, Eric, Kirwan, CC, Kirwan, Cliona; id_orcid, Valle, Juan W., Seifert, B., Swinson, Daniel, Fairbrother, P, Yan, Ying, Clare Wilkinson, Tom Fahey, Shaw, V.E., Fahey, Tom, Hunter, David, Pietsch, Prof Torsten, Wadsley, J., Huang, Annie, Picard, Daniel, Gourley, Charlie, Martin Roland, Cheung, K.L., Adele Francis (16196210), Somers, Gino R., RUSSELL, NIGEL, Rao, Arvind, Faria, Claudia C, Fyfe, D., McCartney, Amelia, Brain, E.G.C., Erker, Craig, Hamilton, W., Russell, Nigel H., Wasan, H, Fleming, Adam J., Campbell, F, Fyfe, David, Harrison, Mark, Clark, Richard E., Sibbering, Mark, Kareclas, P., Canin, Beverly, Neal, R.D., Cheung, K-L, Lulla, Rishi R., Ghaneh, P., Greg Rubin, Knapper, Steve, Morris, Karen, Goldman, Stewart, James Whitlock, Ramsay, David A, Benson, John, Fiona Walter, Calvert, M., Maclead, U., Blazeby, Jane M., Battisti, Nicolò Matteo Luca, McArthur, Grant, Colloca, G., Vaidya, Jayant, Ghaneh, P, Wadsley, Jonathan, Kanesvaran, Ravindran, Kell, Jonathan, Kirwan, Cliona C, Jaspan, Tim, Miller, Paul S.J., Ramsay, David A., Vaidya, JS, Valle, JW, Nick Wadd, Liu, Dong-Xu, Chau, Ian, Stephens, Derek, Ellis, IO, P. Corrie (3534860), Walter, F, Reed, MWR, Corrie, P., Liu, Karen, Kyte, D., Long, Georgina V., Malcolm W. R. Reed (8115854), Rawcliffe, R, Reeve, Bryce B, Roques, T, Wall, L, Reed, Malcolm W R, Jonathan Sussman, Baskin, Berivan,, Rawcliffe, C, Potter, Shelley, Abdel-Fatah, Tarek M.A., Tamas Hickish, Bliss, Judith M., Rees, Charlotte, Geoffrey Mitchell, Eithne Costello, Ramsey I Cutress (10530917), Hickish, Tamas F., Marotti, L., Zimmerman, C., Vedsted, Peter, Madhusudan, S., A. Maraveyas (7644215), Roland, Martin, Wardle, J, Robinson, Angus, Morgan, Yvonne G., Backen, Alison C, Fried, Iris, Wildiers, Hans, Willie Hamilton, Bohumil Seifert, J. A. Bridgewater (7644233), Stuart A McIntosh (10530905), Neoptolemos, John P., Paul Ross, Wadsley, J., Middleton, G. W., Lopes, Andre, Middleton, Gary W, John R. Benson (15213625), Palmer, D.H., Weller, D, Khwaja, Asim, D. H. Palmer (7644203), Robert, Caroline, Walker, David, Harpreet Wasan, Anus, Robinson A, Pockley, Alan G., Wilkinson, C.E., Steward, Will P., Taylor, Michael D., Currow, David C., Stephen Falk, Vedsted, P, Colloca, G, McCartney, A., Battisti, NML, O'Day, Steven, Patel, Poulam M., Valle, Juan, Walter, F., Temel, JS, Green, Andrew R., Flaherty, Keith T, Earle, C., Cutress, Ramsey I., Toledano, Helen, McIntosh, Stuart A; id_orcid, MWR Reed (7752263), Rubin, Greg, Bader, Gary D, Jayant S Vaidya (16266671), Hawkins, Cynthia E., Mansoor, Wasat, Vedsted, P., Steward, Will P, Sidhu, Kally, Fleming, Adam J, David Cunningham, de Wit, N., Rubin, G, Srinivasan, Madhusudan, Dunn, Janet A, Rueda, OM, Cheung, Kwok Leung, Lee, Sandra J, Temel, Jennifer S, S. Beare (7644230), Crawford, S.M., McAdam, K, Watson, Eila, Korc-Grodzicki, Beatriz, Grunfeld, Eva, Bridgewater, John A, Naisbitt, D, Taplin, S, Battisti, N.M.L., Watson, E, Skene, A, Tsang, J., Wilson, Beverly, Carmichael, AR, Jackson, Richard, McIntosh, Stuart A, Bader, Gary D., Kirkwood, John M, Francis, Adele, Mackensen, Andreas, Paula Ghaneh, Sirachainan, Nongnuch, Chan, Jennifer A., Rees, RC, Wilcock, Andrew, Bridgewater, John A., Biganzoli, L, Eggermont, Alexander M M, Coxon, F., de Wit, NJ, Prados, Michael D., Morris, K, Friend, John, Trimboli, RM, Coxon, F, Madhusudan, S, Basch, E., McCartney, A, Taylor, Michael D +847 morecore +1 more sourceProspective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]
, 2013 Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...Klautke, Gunther, Galle, Peter R., Brenner, Baruch, Arnold, Dirk, Roessler, Hans-Peter, Thomaidis, Thomas, Schimanski, Carl Christoph, Schmidberger, Heinz, Rödel, Claus, Gockel, Ines, Möhler, Markus, Trarbach, Tanja, Lang, Hauke +12 morecore +1 more source
