Results 41 to 50 of about 98,224 (178)

A novel prognostic risk score associated with resistance to docetaxel chemotherapy for predicting biochemical recurrence-free survival in patients with prostate cancer

Discover Oncology
Objective To identify molecular clusters and develop a novel prognostic risk score associated with resistance to docetaxel chemotherapy for predicting biochemical recurrence free survival (BCRFS) and tumor immune microenvironment of prostate cancer (PCa).
Desheng Zhu, Hongbin Zhu, Ting Huang, Wentao Fan   +3 more
doaj   +1 more source

Combination therapy in metastatic castration sensitive prostate cancer: A Systematic review and network meta-analysis

Indian Journal of Urology, 2022
Introduction: Studies directly comparing the different combination therapies offered to men with metastatic castration sensitive prostate cancer (mCSPC), are not available yet.
Jatinder Kumar, Muhammad Umar Alam, Seyed Behzad Jazayeri, Karthik Tanneru, Soroush Bazargani, Charu Shastri, Shiva Gautam, Shahriar Koochekpour, Sanjeev Shukla, Mark Bandyk, Joseph Costa, K C Balaji   +11 more
doaj   +1 more source

Clostridium difficile Colitis and Neutropenic Fever Associated with Docetaxel Chemotherapy in a Patient with Advanced Extramammary Paget’s Disease

Case Reports in Dermatology, 2012
Extramammary Paget's disease is a rare cutaneous malignant neoplasm. Previous studies indicated the efficacy of docetaxel in advanced cases. The common side effects of docetaxel are usually tolerable and seldom life-threatening.
Yumi Nonomura, Atsushi Otsuka, Yuichiro Endo, Akihiro Fujisawa, Miki Tanioka, Kenji Kabashima, Yoshiki Miyachi   +6 more
doaj   +1 more source

Relationship Between Docetaxel AUC and Neutropenia in Patients with Breast Cancer

Zhongliu Fangzhi Yanjiu, 2018
Objective To investigate the relationship between docetaxel AUC(area under curve) and neutropenia in patients with breast cancer after chemotherapy. Methods We selected 94 patients with breast cancer who accepted AC sequential T chemotherapy regimen as ...
ZHANG Ni, TIAN Fengqi, HE Baoxia
doaj   +1 more source

Docetaxel Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Apoptosis in Prostate Cancer Cells via Epigenetic Gene Regulation by Enhancer of Zeste Homolog 2

The World Journal of Men's Health, 2023
Purpose: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising cancer therapeutic agent because of its tumor selectivity and its ability to induce apoptosis in cancer cells while sparing most normal cells.
Won Hyeok Lee, Seong Cheol Kim, Song Hee Kim, Ji Hyung Yoon, Kyung Hyun Moon, Sang Hyeon Cheon, Taekmin Kwon, Young Min Kim, Jeong Woo Park, Sang Hun Lee, Jeong Min Lee, Sungchan Park, Benjamin I Chung   +12 more
doaj   +1 more source

Docetaxel enhances lysosomal function through TFEB activation

, 2018
Docetaxel is an effective and commonly used chemotherapeutic drug for cancer. Autophagy has been reported to be involved in the anticancer mechanism of docetaxel. However, the effect of docetaxel on lysosomal function remains elusive.
Liu Yang, Jigang Wang, Han-Ming Shen, Dongsheng Huang, Yin Kwan Wong, Yun Chen, Liqin Lu, Xin Sun, Jianbin Zhang, Liming Wang   +9 more
core   +1 more source

"Docetaxel in adjuvant therapy of breast cancer: results of the TAXIT 216 multicenter trial" [PDF]

, 2008
The dissertation is focused on the evaluation of a Docetaxel-based sequential regimen as adjuvant therapy of breast cancer. Docetaxel is among the most active chemotherapeutic agents for breast cancer.
Forestieri, Valeria
core   +1 more source

Docetaxel-induced pericardial effusion

, 2017
Hypersensitivity reactions, cumulative fluid retention, and neurotoxicity are frequently seen toxicities related to docetaxel. Fluid retention may be present as edema, weight gain, or third place fluid collection. Pericardial effusion is rarely seen with
Alkan, Ali, Mizrak, Dilsa, DEMİRKAZIK, AHMET, Dogan, Serife E.   +3 more
core   +1 more source

Focal Adhesion Kinase Silencing Augments Docetaxel-Mediated Apoptosis in Ovarian Cancer Cells [PDF]

, 2005
Docetaxel causes cell death through induction of apoptosis; however, cell death characteristics for docetaxel have not yet been fully elucidated.
Lutgendorf, Susan K., Halder, Jyotsnabaran, Schmandt, Rosemarie, Nelkin, Gina M., Jennings, Nicholas B., Schaller, Michael D., Sood, Anil K., Landen Jr., Charles N., Li, Yang, Fan, Dominic   +9 more
core   +1 more source

In vivo CRISPR/Cas9 knockout screen: TCEAL1 silencing enhances docetaxel efficacy in prostate cancer

Life Science Alliance, 2020
A whole genome in vivo CRISPR/Cas9 screen identifies TCEAL1 as a potential target to sensitise prostate cancer cells to docetaxel to improve the efficacy of chemotherapy.
Linda K Rushworth, Victoria Harle, Peter Repiscak, William Clark, Robin Shaw, Holly Hall, Martin Bushell, Hing Y Leung, Rachana Patel   +8 more
doaj   +1 more source