Results 51 to 60 of about 98,224 (178)

How nanotechnology can enhance docetaxel therapy

open access: yes, 2013
Li Zhang, Na ZhangSchool of Pharmaceutical Science, Shandong University, Shandong Province, People's Republic of ChinaAbstract: Docetaxel has been recognized as one of the most efficient anticancer drugs over the past decade; however, its poor water ...
Zhang N, Zhang L
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ABA enhances the apoptotic effect of docetaxel in the multidrug-resistant DU145 prostate cancer cell line [PDF]

open access: yesArchives of Biological Sciences
This study aimed to induce drug resistance in DU145 prostate cancer cells by exposing them to docetaxel and mitoxantrone, and to examine the effects of combining docetaxel and abscisic acid (ABA).
Şumnulu Deniz, Doğanlar Zeynep Banu
doaj   +1 more source

MAOA expression inhibits docetaxel cytotoxicity.

open access: yes, 2014
(A) PC3 cells expressing MAOA exhibit enhanced cell survival following 48 and 72 hours of exposure to docetaxel ...
Ryan R. Gordon (626946)   +14 more
core   +1 more source

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile

open access: yes, 2017
Pedram Rafiei, Azita Haddadi Division of Pharmacy, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada Abstract: Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer types.
Rafiei P, Haddadi A
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Predictors of Toxicity of Weekly Docetaxel in Chemotherapy-Treated Non- Small Cell Lung Cancers

open access: yes, 2011
Weekly docetaxel. seems to be safe and effective compared with traditional triweekly docetaxel. as a second-line treatment for non-small cell lung cancer. However, the risk factors for severe toxicity of weekly docetaxel in this group of patients are not
CHEN, JO-PAI;LO, YIN;YU, CHONG-JEN;HSU, CHIUN;SHIH, JIN-YUAN;YANG, CHIH-HSIN;YANG, CHIH- HSIN   +1 more
core   +1 more source

EGFR‐mediated hyperacetylation of tubulin induced docetaxel resistance by downregulation of HDAC6 and upregulation of MCAK and PLK1 in prostate cancer cells

open access: yesKaohsiung Journal of Medical Sciences
Docetaxel‐based chemotherapy has generally been considered as one of the effective treatments for castration‐resistant prostate cancer (PCa). However, clinical treatment with docetaxel often encounters a number of undesirable effects, including drug ...
Yeong‐Shiau Pu   +10 more
doaj   +1 more source

Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK

open access: yesJournal of Experimental & Clinical Cancer Research, 2011
Objective To investigate the effects of ulinastatin and docetaxel on invasion of breast cancer cells and expression of uPA, uPAR and ERK, breast cancer MDA-MB-231 and MCF-7 cells.
Wang Hong   +6 more
doaj   +1 more source

Early clinical studies with docetaxel. Docetaxel Investigators Group.

open access: yes, 1995
Docetaxel has been evaluated in six phase I studies involving a total of 234 patients with a wide variety of tumour types (50% had breast or ovarian cancer).
Aapro M, Bruno R
core   +1 more source

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

open access: yesInterdisciplinary Medicine
Docetaxel remains a mainstay in the treatment of prostate cancer; however, docetaxel resistance continues to pose a major challenge and is associated with unfavorable patient outcomes.
Yishan Zhang   +11 more
doaj   +1 more source

Docetaxel treatment in the elderly patient with hormone refractory prostate cancer

open access: yes, 2008
Victoria J SinibaldiSidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MA, USAAbstract: Docetaxel is an anti-microtubular agent in the family of the taxanes, now FDA approved as first line chemotherapy for the treatment of hormone ...
Victoria J Sinibaldi
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