Results 251 to 260 of about 697,276 (400)

Advanced modeling of salt-inducible kinase (SIK) inhibitors incorporating protein flexibility through molecular dynamics and cross-docking. [PDF]

Sci Rep
Valdés-Albuernes JL, Díaz-Pico E, Alfaro S, Caballero J.   +3 more
europepmc   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

Advanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang, Yuan Fang, Xiaoming Qin, Yiwei Zhang, Bo Kang, Li Zhong, Baoxin Liu, Jiachen Luo, Yidong Wei   +8 more
wiley   +1 more source

Rehabilitation of Registered Dock Workers [PDF]

, 1971
R J Blow, John M. Jackson
openalex   +3 more sources

Assessing interaction recovery of predicted protein-ligand poses. [PDF]

J Cheminform
Errington D, Schneider C, Bouysset C, Dreyer FA.   +3 more
europepmc   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

DISCUSSION. H.M. DOCKYARD, DEVONPORT ; WIDENING OF No10 DOCK. MARITIME AND WATERWAYS ENGINEERING DIVISION. [PDF]

, 1947
D P BERTLIN, C PEEL, G A WILSON, H RIDEHALGH, J H JELLETT, T L COFFIN, C F ARMSTRONG, R W A FANE, JA HOOPER, J C DICKINSON, J M P HOOLEY, R G KEEVIEL, E. G. Walker   +12 more
openalex   +1 more source

Correction: Screening potential anti-osteoarthritis compounds using molecular docking based on MAPK and NFκB pathways and validating their anti-osteoarthritis effect. [PDF]

PLoS One
Zhu TW, Zheng Y, Li RX.
europepmc   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Load strain-gage test of 150-ton floating crane for the Bureau of Yards and Docks, U. S. Navy Department.

, 1920
Louis J. Larson, R Templin
openalex   +1 more source

Special Issue: Discovery of Bioactive Phytochemicals' Molecular Mechanisms Against Different Diseases Based on Network Pharmacology and Molecular Docking. [PDF]

Int J Mol Sci
Xu B.
europepmc   +1 more source