Results 1 to 10 of about 2,926,121 (366)

Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema

Drug Design, Development and Therapy, 2023
Yuan Cui,1,2 Jingyi Hu,2 Yanan Li,1,2 Ryan Au,1,2 Yulai Fang,2 Cheng Cheng,1 Feng Xu,1,2 Weiyang Li,1,2 Yuguang Wu,1,2 Lei Zhu,2 Hong Shen2 1Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Affiliated Hospital of Nanjing ...
Cui Y, Hu J, Li Y, Au R, Fang Y, Cheng C, Xu F, Li W, Wu Y, Zhu L, Shen H   +10 more
doaj   +6 more sources

Improving survival, growth rate, and animal welfare in piglets by avoiding teeth shortening and tail docking [PDF]

Journal of Veterinary Behavior, 2012
Piglets are subjected to several painful procedures during their first week of life, including ear tagging, teeth clipping or grinding (although routinely prohibited in Europe), tail docking (although routinely prohibited in Europe), needle injections (vaccination and iron injection), and castration might be performed for male piglets.
Van Beirendonck, Sanne, Driessen, Bert, Verbeke, Geert, Permentier, Liesbet, Van de Perre, Vincent, Geers, Rony   +5 more
semanticscholar   +5 more sources

A comprehensive study on the impact of <i>Ligustrum vicaryi</i> L. fruit polysaccharide on myocardial fibrosis through animal experiments, network pharmacology and molecular docking. [PDF]

Front Cardiovasc Med
BackgroundMyocardial fibrosis (MF) is a prevalent pathological condition associated with various heart diseases, such as heart failure and arrhythmias, which disrupt electrical signals and reduce pumping efficiency. This research explored the therapeutic effects and potential mechanisms of Ligustrum vicaryi L.
Liu S, Liu M, Wang J, Rong R, Gao Y, Li X, Liu X, Li S.   +7 more
europepmc   +5 more sources

Integrated network pharmacology, molecular docking, and animal experiments to reveal the potential mechanism of hesperetin on COPD [PDF]

Scientific Reports
Hesperetin (HE), a natural flavonoid exhibiting anti-inflammatory and antioxidant properties, holds significant potential in treating chronic obstructive pulmonary disease (COPD).
Jingxi Wang, Hongyang Wang, Xin Kang, Xiaotian Wang, Xi Li, Jie Guo, Xuan Jing, Xi Chu, Xue Han   +8 more
doaj   +3 more sources

Why are most EU pigs tail docked? Economic and ethical analysis of four pig housing and management scenarios in the light of EU legislation and animal welfare outcomes

Animal, 2016
To limit tail biting incidence, most pig producers in Europe tail dock their piglets. This is despite EU Council Directive 2008/120/EC banning routine tail docking and allowing it only as a last resort.
R.B. D’Eath, J.K. Niemi, B. Vosough Ahmadi, K.M.D. Rutherford, S.H. Ison, S.P. Turner, H.T. Anker, T. Jensen, M.E. Busch, K.K. Jensen, A.B. Lawrence, P. Sandøe   +11 more
doaj   +7 more sources

Sedative-hypnotic-like effect and molecular docking of di-naphthodiospyrol from Diospyros lotus in an animal model

Biomedicine & Pharmacotherapy, 2017
Diospyros lotus Linn commonly known as date-plum, or Caucasian persimmon has multiple uses in folk medicine. Various parts of this plant is used for alleviating lumbago, dysponea, hemorrhage, insomnia, and hiccup. The plant extracts possess a variety of biological activities, such as anti-inflammatory, sedative, febrifuge, anti-microbial, vermifuge ...
Ghias Uddin, Seema Patel, Mohammad S. Mubarak, Horacio Pérez-Sánchez, José P. Cerón-Carrasco, Yahia N. Mabkhot, Haroon Khan, Abdur Rauf, Jorge Peña-García, Saud Bawazeer, Taibi Ben Hadda, Tareq Abu-Izneid   +11 more
semanticscholar   +4 more sources

Anti-hyperalgesic effect of Lippia grata leaf essential oil complexed with β-cyclodextrin in a chronic musculoskeletal pain animal model: Complemented with a molecular docking and antioxidant screening

Biomedicine & Pharmacotherapy, 2017
Due to its unclear pathophysiology, the pharmacological treatment of fibromyalgia is a challenge for researchers. Studies using medicinal plants, such as those from the genus Lippia, complexed with cyclodextrins (CDs) have shown innovative results.The present research intended to evaluate the effect of an inclusion complex containing β-cyclodextrin ...
Gokhan Zengin, Henrique Douglas Melo Coutinho, Lucindo José Quintans-Júnior, Abdurrahman Aktumsek, Jullyana S.S. Quintans, Adriano Antunes de Souza Araújo, Pollyana S. Siqueira-Lima, Paula dos Passos Menezes, Priscila L. Santos, Marcus Tullius Scotti, Luciana Scotti, Irwin Rose Alencar de Menezes, Angélica Maria Lucchesi, Renan G. Brito, Heitor G. Araújo-Filho, Angelo R. Antoniolli   +15 more
semanticscholar   +4 more sources

Molecular docking studies on α-amylase inhibitory peptides from milk of different farm animals [PDF]

Journal of Dairy Science, 2023
Milk derived peptides have emerged as a popular mean to manage various lifestyle disorders such as diabetes. Fermentation is being explored as one of the faster and efficient way of producing peptides with antidiabetic potential. Therefore, in this study an attempt was made to comparatively investigate the α-amylase (AA) inhibitory properties of ...
Mudgil, P, Al Dhaheri, MKO, Alsubousi, MSM, Khan, H, Redha, AA, Yap, P-G, Gan, C-Y, Maqsood, S   +7 more
openaire   +5 more sources

SARS-CoV-2 prevalence in domestic and wildlife animals: A genomic and docking based structural comprehensive review [PDF]

Heliyon, 2023
The SARS-CoV-2 virus has been identified as the infectious agent that led to the COVID-19 pandemic, which the world has seen very recently. Researchers have linked the SARS-CoV-2 outbreak to bats for the zoonotic spread of the virus to humans. Coronaviruses have a crown-like shape and positive-sense RNA nucleic acid.
Tuhin Das, Suranjana Sikdar, Md. Helal Uddin Chowdhury, Khandakar Jannatul Nyma, Md. Adnan   +4 more
openaire   +4 more sources

Tail docking and animal welfare [PDF]

The Bovine Practitioner, 2004
Tail docking is a common practice on many dairy farms, and is perceived by many farmers to improve cleanliness and enhance milking parlour efficiency. It is a controversial practice attracting increasing scrutiny by the animal welfare community. Scientific studies have been performed to evaluate physiological and behavioural responses to tail docking ...
P.L. Ruegg
openaire   +3 more sources