Results 1 to 10 of about 2,884,567 (307)

Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema

Drug Design, Development and Therapy, 2023
Yuan Cui,1,2 Jingyi Hu,2 Yanan Li,1,2 Ryan Au,1,2 Yulai Fang,2 Cheng Cheng,1 Feng Xu,1,2 Weiyang Li,1,2 Yuguang Wu,1,2 Lei Zhu,2 Hong Shen2 1Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Affiliated Hospital of Nanjing ...
Cui Y, Hu J, Li Y, Au R, Fang Y, Cheng C, Xu F, Li W, Wu Y, Zhu L, Shen H   +10 more
doaj   +6 more sources

Improving survival, growth rate, and animal welfare in piglets by avoiding teeth shortening and tail docking [PDF]

Journal of Veterinary Behavior, 2012
Piglets are subjected to several painful procedures during their first week of life, including ear tagging, teeth clipping or grinding (although routinely prohibited in Europe), tail docking (although routinely prohibited in Europe), needle injections (vaccination and iron injection), and castration might be performed for male piglets.
Sanne Van Beirendonck, Bert Driessen, Geert Verbeke, Liesbet Permentier, Vincent Van de Perre, R. Geers   +5 more
semanticscholar   +4 more sources

Sedative-hypnotic-like effect and molecular docking of di-naphthodiospyrol from Diospyros lotus in an animal model

Biomedicine & Pharmacotherapy, 2017
Diospyros lotus Linn commonly known as date-plum, or Caucasian persimmon has multiple uses in folk medicine. Various parts of this plant is used for alleviating lumbago, dysponea, hemorrhage, insomnia, and hiccup. The plant extracts possess a variety of biological activities, such as anti-inflammatory, sedative, febrifuge, anti-microbial, vermifuge ...
Abdur Rauf, Taïbi Ben Hadda, Ghias Uddin, José P. Cerón‐Carrasco, Jorge Peña‐García, Horacio Pérez‐Sánchez, Haroon Khan, Saud Bawazeer, Seema Patel, Mohammad S. Mubarak, Tareq Abu‐Izneid, Yahia N. Mabkhot   +11 more
semanticscholar   +4 more sources

Integrated network pharmacology, molecular docking, and animal experiments to reveal the potential mechanism of hesperetin on COPD

Scientific Reports
Hesperetin (HE), a natural flavonoid exhibiting anti-inflammatory and antioxidant properties, holds significant potential in treating chronic obstructive pulmonary disease (COPD).
Jingxi Wang, Hongyang Wang, Xin Kang, Xiaotian Wang, Xi Li, Jie Guo, Xuan Jing, Xi Chu, Xue Han   +8 more
doaj   +4 more sources

Anti-hyperalgesic effect of Lippia grata leaf essential oil complexed with β-cyclodextrin in a chronic musculoskeletal pain animal model: Complemented with a molecular docking and antioxidant screening

Biomedicine & Pharmacotherapy, 2017
Due to its unclear pathophysiology, the pharmacological treatment of fibromyalgia is a challenge for researchers. Studies using medicinal plants, such as those from the genus Lippia, complexed with cyclodextrins (CDs) have shown innovative results.The present research intended to evaluate the effect of an inclusion complex containing β-cyclodextrin ...
Pollyana S. Siqueira-Lima, Renan Guedes de Brito, Heitor G. Araújo-Filho, Priscila L. Santos, Angélica Maria Lucchesi, Adriano Antunes de Souza Araújo, Paula dos Passos Menezes, Luciana Scotti, Luciana Scotti, Irwin Rose Alencar de Menezes, Henrique Douglas Melo Coutinho, Gökhan Zengin, Abdurrahman Aktumsek, Ângelo R. Antoniolli, Lucindo José Quíntans-Júnior, Jullyana de Souza Siqueira Quintans   +15 more
semanticscholar   +4 more sources

Molecular docking studies on α-amylase inhibitory peptides from milk of different farm animals [PDF]

Journal of Dairy Science, 2023
Milk-derived peptides have emerged as a popular mean to manage various lifestyle disorders such as diabetes. Fermentation is being explored as one of the faster and efficient way of producing peptides with antidiabetic potential. Therefore, in this study, an attempt was made to comparatively investigate the pancreatic α-amylase (PAA) inhibitory ...
Priti Mudgil, Mouza Khamis Obaid Al Dhaheri, Maitha Saif Mohammed Alsubousi, Hina Khan, Ali Ali Redha, Pei-Gee Yap, Chee‐Yuen Gan, Sajid Maqsood   +7 more
openalex   +5 more sources

SARS-CoV-2 prevalence in domestic and wildlife animals: A genomic and docking based structural comprehensive review [PDF]

Heliyon, 2023
The SARS-CoV-2 virus has been identified as the infectious agent that led to the COVID-19 pandemic, which the world has seen very recently. Researchers have linked the SARS-CoV-2 outbreak to bats for the zoonotic spread of the virus to humans. Coronaviruses have a crown-like shape and positive-sense RNA nucleic acid.
Tuhin Das, Suranjana Sikdar, Md. Helal Uddin Chowdhury, Khandakar Jannatul Nyma, Md. Adnan   +4 more
openalex   +4 more sources

Tail docking and animal welfare [PDF]

The Bovine Practitioner, 2004
Tail docking is a common practice on many dairy farms, and is perceived by many farmers to improve cleanliness and enhance milking parlour efficiency. It is a controversial practice attracting increasing scrutiny by the animal welfare community. Scientific studies have been performed to evaluate physiological and behavioural responses to tail docking ...
P.L. Ruegg
openalex   +3 more sources

Design, Synthesis, Evaluation, and Molecular Docking Study of Ascorbic Acid Dual-Coated Omeprazole Pellets and the Antioxidative Effect of Ascorbic Acid on Omeprazole-Induced Renal Injury in an Animal Model [PDF]

ACS Omega, 2023
The present study was carried out to investigate the antioxidant effect of ascorbic acid on omeprazole (O.P.)-induced acute kidney infection (AKI). Design of experiment (DoE) was employed to fabricate formulations (P1-P8) by the extrusion spheronization technique, and they were evaluated using various analytical techniques.
Hina Raza, Ali Abrar, Asmara Ashraf, Suryyia Manzoor, Rahat Shamim, Farhan Siddique, Ahmad Mohammad Salamatullah, Mohammed Bourhia, Gezahign Fentahun Wondmie   +8 more
openalex   +4 more sources

Exploring the mechanism of anti-fatigue of resveratrol based on network pharmacology and molecular docking, and in vitro studies

Scientific Reports, 2023
To investigate the potential mechanism of resveratrol in anti-fatigue by network pharmacology and molecular docking, and to investigate the anti-fatigue efficacy of resveratrol through in vitro animal experiments.
Peipei Ma, Jinlei Li, Qing Huang, Shijie Wei, Hurong Ge, Zhizhong Wang   +5 more
doaj   +2 more sources