Results 31 to 40 of about 2,926,121 (366)

Mechanism of Bazhen decoction in the treatment of colorectal cancer based on network pharmacology, molecular docking, and experimental validation

Frontiers in Immunology, 2023
Objective Bazhen Decoction (BZD) is a common adjuvant therapy drug for colorectal cancer (CRC), although its anti-tumor mechanism is unknown. This study aims to explore the core components, key targets, and potential mechanisms of BZD treatment for CRC ...
Shuai Lu, Xibo Sun, Zhongbao Zhou, Huazhen Tang, Ruixue Xiao, Qingchen Lv, Bing Wang, Jinxiu Qu, Jinxuan Yu, Fang Sun, Zhuoya Deng, Yuying Tian, Cong Li, Zhenpeng Yang, Penghui Yang, Benqiang Rao   +15 more
semanticscholar   +1 more source

Neuroprotective Effect of Methanolic Ajwa Seed Extract on Lipopolysaccharide-Induced Memory Dysfunction and Neuroinflammation: In Vivo, Molecular Docking and Dynamics Studies

Plants, 2023
Islamic literature has indicated that daily consumption of Ajwa dates heals a variety of chronic diseases and disorders. The current research investigates the neuroprotective effect of methanolic Ajwa seed extract (MASE) on lipopolysaccharide (LPS ...
V. Mani, Minhajul Arfeen, D. Dhaked, H. Mohammed, P. Amirthalingam, Hossam A Elsisi   +5 more
semanticscholar   +1 more source

Nelumbo nucifera Gaertn. leaves: network pharmacology and molecular docking analysis of active ingredients and their mechanisms of action in treating atherosclerosis

Biotechnology & Biotechnological Equipment, 2022
Atherosclerosis is the pathological basis of cardiovascular and cerebrovascular diseases. Nelumbo nucifera Gaertn. leaves are edible, an effective traditional Chinese medicine in the treatment of atherosclerosis, but its mechanisms of action remain ...
Linhai Wang, Zhuoji Guan, Shaodong Li, Xin Dong, Jialin Jiang, Lingjun Wang, Shaoxiang Xian   +6 more
doaj   +1 more source

Government response to UK Farm Animal Welfare Council report on castration and tail docking of lambs

Animal Welfare, 2009
E Carter
openaire   +2 more sources

Acclimation and Blood Sampling: Effects on Stress Markers in C57Bl/6J Mice

Animals, 2023
Blood sampling in rodents is common practice in scientific studies. Some of the refined methods widely used are the puncture of the saphenous vein or tail vein, or even tail docking.
Nerea Marin, Amparo Moragon, Domingo Gil, Francisco Garcia-Garcia, Viviana Bisbal   +4 more
doaj   +1 more source

An integrative reverse vaccinology, immunoinformatic, docking and simulation approaches towards designing of multi-epitopes based vaccine against monkeypox virus

Journal of Biomolecular Structure and Dynamics, 2022
Monkeypox is a viral zoonotic disease that is caused by the monkeypox virus (MPXV) and is mainly transmitted to human through close contact with an infected person, animal, or fomites which is contaminated by the virus.
Asad Ullah, Farah Shahid, M. Haq, Muhammad Tahir ul Qamar, Muhammad Irfan, B. Shaker, Sajjad Ahmad, Faris A Alrumaihi, Khaled S. Allemailem, A. Almatroudi   +9 more
semanticscholar   +1 more source

Ganoderic acid C2 exerts the pharmacological effects against cyclophosphamide-induced immunosuppression: a study involving molecular docking and experimental validation

Scientific Reports, 2023
Triterpenoids, as the main active ingredient of Ganoderma lucidum fermented extract, exert multiple pharmacological activities, including immunomodulatory properties.
Yuchen Liu, Dongsheng Tan, Hong Cui, Jihua Wang   +3 more
doaj   +1 more source

Biological Effect of Quercetin in Repairing Brain Damage and Cerebral Changes in Rats: Molecular Docking and In Vivo Studies

BioMed Research International, 2022
This study examined the protective effect of quercetin against high-altitude-induced brain damage in rats. A molecular docking study was performed to investigate the potential effect of quercetin in reducing brain damages through its ability to target ...
Ahmed B. M. Mehany, A. Belal, Eman Y. Santali, S. Shaaban, Mohammad A S Abourehab, Ola A El-Feky, Mahmoud Diab, F. M. Abou Galala, E. Elkaeed, Ghada Abdelhamid   +9 more
semanticscholar   +1 more source

Purification, Identification and Molecular Docking of Immunomodulatory Peptides from the Heads of Litopenaeus vannamei

Foods, 2022
In order to realize the high-value utilization of Litopenaeus vannamei (L. vannamei) heads, immunomodulatory peptides were prepared from the enzymatic hydrolysate of L.
Weiwei Jiang, Keyu Ren, Zhiyan Yang, Zhou Fang, Yan Li, Xiaoxue Xiang, Yishan Song   +6 more
semanticscholar   +1 more source

Clove Flower Extract (Syzygium aromaticum) Has Anticancer Potential Effect Analyzed by Molecular Docking and Brine Shrimp Lethality Test (BSLT)

Veterinary Medicine International, 2022
Various anticancer medications have been discovered due to advances in the health care industry, but they have undesirable side effects. On the other hand, anticancer drugs derived from natural sources have low side effects, making them excellent for ...
E. Aksono, Aprilia Cahya Latifah, L. T. Suwanti, K. U. Haq, Herinda Pertiwi   +4 more
semanticscholar   +1 more source