Results 21 to 30 of about 3,160,114 (308)

JIT, truck docks, and simulation [PDF]

1988 Winter Simulation Conference Proceedings, 1988
Changes in manufacturing and distribution strategies have changed the shipping/receiving functions into an integral part of the production process. As a result of this change, the performance requirements and standards for truck docks have changed. To meet those standards, many shipping/receiving docks have automated. This automation affects the entire
openaire   +2 more sources

Synthesis and Structure Elucidation of Two Essential Metal Complexes: In-Vitro Studies of Their BSA/HSA-Binding Properties, Docking Simulations, and Anticancer Activities

Molecules, 2022
Imidazole and tetrazole derivatives are widely used as clinical drugs since they possess a variety of pharmaceutical function. Zinc and iron are essential trace elements of the human body, with less toxicity and good biocompatibility.
Jun-Li Guo, Guang-Yu Liu, Rui-Ying Wang, Shu-Xiang Sun   +3 more
doaj   +1 more source

Simulation and cross docking [PDF]

Winter Simulation Conference Proceedings, 1995., 1995
Cross docking is a material handling and distribution concept in which goods move directly from receiving to shipping. In a typical cross docking system, the primary objective is to eliminate storage and excessive handling. As companies continue to streamline distribution functions, cross docking is becoming a more widely accepted distribution method ...
openaire   +1 more source

Molecular Docking Simulations for Macromolecularly Imprinted Polymers [PDF]

Industrial & Engineering Chemistry Research, 2011
Molecularly imprinted polymers are fully synthetic antibody mimics prepared via the crosslinking of organic monomers in the presence of an analyte. This general procedure is now well developed for small molecule templates; however, attempts to extend the same techniques to the macromolecular regime have achieved limited success to date.
David R, Kryscio, Yue, Shi, Pengyu, Ren, Nicholas A, Peppas   +3 more
openaire   +2 more sources

5,8-Dimethyl-9H-carbazole Derivatives Blocking hTopo I Activity and Actin Dynamics

Pharmaceuticals, 2023
Over the years, carbazoles have been largely studied for their numerous biological properties, including antibacterial, antimalarial, antioxidant, antidiabetic, neuroprotective, anticancer, and many more. Some of them have gained great interest for their
Jessica Ceramella, Domenico Iacopetta, Anna Caruso, Annaluisa Mariconda, Anthi Petrou, Athina Geronikaki, Camillo Rosano, Carmela Saturnino, Alessia Catalano, Pasquale Longo, Maria Stefania Sinicropi   +10 more
doaj   +1 more source

Syntheses and Glycosidase Inhibitory Activities, and in Silico Docking Studies of Pericosine E Analogs Methoxy-Substituted at C6

Marine Drugs, 2020
Inspired by the significant α-glucosidase inhibitory activities of (+)- and (−)-pericosine E, we herein designed and synthesized 16 analogs of these marine natural products bearing a methoxy group instead of a chlorine atom at C6. Four of these compounds
Yoshihide Usami, Megumi Higuchi, Koji Mizuki, Mizuki Yamamoto, Mao Kanki, Chika Nakasone, Yuya Sugimoto, Makio Shibano, Yoshihiro Uesawa, Junko Nagai, Hiroki Yoneyama, Shinya Harusawa   +11 more
doaj   +1 more source

Anti-Browning Effect of 2-Mercaptobenzo[d]imidazole Analogs with Antioxidant Activity on Freshly-Cut Apple Slices and Their Highly Potent Tyrosinase Inhibitory Activity

Antioxidants, 2023
Ten 2-mercaptobenzimidazole (2-MBI) analogs were synthesized as potential tyrosinase inhibitors because mercapto-containing compounds can bind to copper ions at the active site of tyrosinase to inhibit enzyme activity.
Jieun Lee, Hye Soo Park, Hee Jin Jung, Yu Jung Park, Min Kyung Kang, Hye Jin Kim, Dahye Yoon, Sultan Ullah, Dongwan Kang, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon   +12 more
doaj   +1 more source

Graphics processing unit accelerated coarse-grained protein-protein docking [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves [187]-202).In this work, we describe a Graphics processing unit (GPU) implementation of the Kim-Hummer coarse-grained model for protein docking simulations, using a Replica Exchange Monte ...
Tunbridge, Ian William
core   +1 more source

Evaluation of Isoflavones as Bone Resorption Inhibitors upon Interactions with Receptor Activator of Nuclear Factor-κB Ligand (RANKL)

Molecules, 2020
Receptor activator of nuclear factor-κB ligand (RANKL) is a cytokine responsible for bone resorption. It binds its receptor RANK, which activates osteoporosis.
Małgorzata Zakłos-Szyda, Grażyna Budryn, Joanna Grzelczyk, Horacio Pérez-Sánchez, Dorota Żyżelewicz   +4 more
doaj   +1 more source

Simulasi Inhibisi Aktivitas Enzim α-Amilase dan α-Glukosidase oleh Senyawa Bioaktif Mikroalga Spirulina platensis

Alchemy, 2023
Diabetes Melitus (DM) Tipe 2 merupakan penyakit dengan gejala hiperglikemia dengan jumlah kasus yang meningkat setiap harinya pada populasi dunia. Enzim yang berperan terkait DM Tipe 2 yaitu α-amilase dan α-glukosidase yang bertindak dalam menghidrolisis
Syafrizayanti Syafrizayanti, Adetya Putri, Marniati Salim, Arif Juliari Kusnanda   +3 more
doaj   +1 more source