NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress. [PDF]
Lin M +12 more
europepmc +1 more source
ω‐3PUFAs Inhibit Gallbladder Cancer Through Enhancing STK31 Methylation
ABSTRACT Gallbladder cancer (GBC) is an aggressive malignancy with limited treatment options. ω‐3PUFAs have known anticancer activity, but their role in GBC remains unclear. The anti‐GBC effects of ω‐3PUFAs (DHA/EPA) were evaluated using in vitro assays and mouse xenograft models.
Shuang‐Xing Li +16 more
wiley +1 more source
Antioxidants rescue murine mesangial cells from docosahexaenoic acid-induced ferroptosis. [PDF]
Saschin L +9 more
europepmc +1 more source
Abstract The leucine‐rich repeat‐containing G protein‐coupled receptor 6 (LGR6) has a potential role in inflammation resolution and different cancer processes. In this study, we employed computational techniques, including molecular docking and molecular dynamics simulations of mammalian membrane‐embeded systems, to understand the activation mechanism ...
Álex Pérez‐Sánchez +3 more
wiley +1 more source
Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on Hematological and Oxidative Stress Markers of Female Wistar Rats With 7,12-Dimethylbenz[a]anthracene-Induced Breast Cancer. [PDF]
Djikeng FT +3 more
europepmc +1 more source
No abstract is available for this article.
wiley +1 more source
Meta Analysis of DHA and EPA Supplementation on Cardiovascular Outcomes and Atrial Fibrillation Risk
ABSTRACT Cardiovascular diseases (CVD) remain to impose a main global burden of morbidity and mortality despite advances in anticipation and treatment. Omega‐3 fatty acids, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been extensively studied for potential cardioprotective effects, yet their impact on cardiovascular outcomes ...
Sepideh Karkon Shayan +12 more
wiley +1 more source
Docosahexaenoic acid is comparable to vildagliptin in improving hyperglycemia and pancreatic insulin signaling of diabetic rats via SIRT1/Akt/PI3K pathway. [PDF]
Abo-Saif MA +3 more
europepmc +1 more source
Early‐life intake of nutritional additives, particularly during pregnancy and the early postnatal period, reduces the risk of Helicobacter pylori infection (HPI) in children by enhancing immune function and preventing gastrointestinal infections through proper nutrition, supporting the “(Pre‐)Fetal origins of HPI” hypothesis through the “gut–uterine ...
Chan Lu +5 more
wiley +1 more source
Maternal docosahexaenoic acid supplementation shapes offspring gut microbiota to modulate the gut-brain axis in a sow-piglet model. [PDF]
Lee S +6 more
europepmc +1 more source

