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Lipids, docosahexaenoic acid (DHA), and traumatic brain injury

2023
Traumatic brain injury (TBI) is one of the leading causes of death or disability in incidents of trauma. It continues to be clinically challenging to find absolute treatments that can manage and control all aspects of secondary injury post-TBI. While some fat diets, like high-fat diet (HFD), are bad, emerging evidence suggests that early treatment with
Darwish, Batoul   +4 more
openaire   +2 more sources

Docosahexaenoic acid (DHA) and human platelet reactivity

The Journal of Nutritional Biochemistry, 1991
This article wil review the evidence to date using human platelets which indicates that docosahexaenoic acid, in addition to the more well-known effects of eicosapentaenoic acid, may contribute to the dampened platelet reactivity observed following fish/fish oil feeding.
Douglas C. Gaudette, Bruce J. Holub
openaire   +1 more source

The Importance Of Docosahexaenoic Acid (DHA) For Child Development

2023
Long-chain polyunsaturated fatty acids (LMPIC), such as those of the n-3 family, represented by eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have relevant physiological and biochemical functions in human metabolism and health. DHA, specifically, is a key nutrient for childhood growth and development because of its primary role in the ...
Pedro Rocha Magalhães   +5 more
openaire   +1 more source

Docosahexaenoic acid (DHA) and cardiovascular disease risk factors

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2009
Numerous epidemiological and controlled interventional trials have supported the health benefits of long-chain omega-3 fatty acids in the form of docosahexaenoic acid (DHA, 22:6n-3) plus eicosapentaenoic acid (EPA, 20:5n-3) from fish and fish oils as well as from algal sources.
openaire   +2 more sources

Docosahexaenoic acid (DHA) attenuated paraquat induced lung damage in mice

Inhalation Toxicology, 2013
Accumulating evidences have proposed the critical roles of oxidative stress in the etiology of lung injury caused by paraquat (PQ). Docosahexaenoic acid (DHA) is an essential n-3 polyunsaturated fatty acid (PUFA), which has been proved to possess prominent antioxidative and anti-inflammatory effects.The aim of this study was to evaluate effects of DHA ...
Jingjing, Chen   +5 more
openaire   +2 more sources

Docosahexaenoic Acid (DHA) Supplementation of Orange Juice Increases Plasma Phospholipid DHA Content of Children

Journal of the American Dietetic Association, 2009
The major dietary source of docosahexaenoic acid (DHA) is fish, which is not widely consumed by children. There is concern, therefore, that children may not receive adequate DHA and so might benefit from dietary supplementation. The aim of the present study was to evaluate the effects of providing a supplement of microencapsulated algal DHA in juice ...
Keli M, Hawthorne   +2 more
openaire   +2 more sources

Effect of docosahexaenoic acid (DHA) on arachidonic acid metabolism and platelet function

Biochemical and Biophysical Research Communications, 1983
Studies from our laboratory have suggested a role for ferrous iron in the metabolism of arachidonic acid and demonstrated that inhibitors of prostaglandin synthesis exert their effect by complexing with the heme group of cyclooxygenase. Docosahexaenoic acid (DHA) is a potent competitive inhibitor of arachidonic acid metabolism by sheep vesicular gland ...
G H, Rao, E, Radha, J G, White
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Maternal docosahexaenoic acid (DHA) supplementation and fetal DHA accretion

2001
Docosahexaenoic acid (DHA) (C22;6n-3) is a polyunsaturated fatty acid that is an essential constituent of cell membranes, particularly of the nervous system where it is found in relatively high concentrations in the brain and retina. In this study expectant mothers were supplied with preformed DHA, at a dosage comparable with current dietary ...
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Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids

Applied Microbiology and Biotechnology, 2016
Thraustochytrids have been applied for industrial production of the omega-3 fatty acid docosahexaenoic (DHA) since the 1990s. During more than 20 years of research on this group of marine, heterotrophic microorganisms, considerable increases in DHA productivities have been obtained by process and medium optimization.
Inga Marie, Aasen   +6 more
openaire   +2 more sources

Endogenous Docosahexaenoic Acid (DHA) Prevents Aβ1–42 Oligomer-Induced Neuronal Injury

Molecular Neurobiology, 2015
The intake of the polyunsaturated fatty acid docosahexaenoic acid (DHA) or n-3 fatty acid has been associated with reduced risk of Alzheimer's disease (AD) in epidemiological reports. However, the underlying mechanism remains to be elucidated. Here, we report that exogenous DHA administration could protect neurons against Aβ oligomer-induced injury ...
Yuan, Tan   +9 more
openaire   +2 more sources

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