Results 31 to 40 of about 31,499 (264)

Reconsidering the Barefoot Doctor Programme [PDF]

Fudan Journal of the Humanities and Social Sciences, 2015
This paper examines the widely acclaimed Barefoot Doctor campaign in China. The Barefoot Doctor campaign has come to symbolise the success of Chinese health care to the extent that it has become a model for WHO public health strategy. Yet little has been done to understand how or whether it worked on the ground and what difficulties and contradictions ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Ecological brain: reframing the study of human behaviour and cognition

Royal Society Open Science
The last decade has seen substantial advances in the capacity to record behaviour and neural activity in humans in real-world settings, to simulate real-world situations in laboratory settings and to apply sophisticated analyses to large-scale data ...
Gabriella Vigliocco, Laura Convertino, Sara De Felice, Lara Gregorians, Viktor Kewenig, Marie A. E. Mueller, Sebastijan Veselic, Mirco Musolesi, Andrew Hudson-Smith, Nicholas Tyler, Eirini Flouri, Hugo J. Spiers   +11 more
doaj   +1 more source

Settlement History of the Middle Tisza Region in the 4th–6th centuries AD

Dissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2019
of PhD thesis submitted in 2018 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of Tivadar Vida.
Zsófia Masek
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Animal remains from the mid 12th–13th century (Árpád Period) village of Kána, Hungary

Dissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2015
of PhD thesis submitted in 2014 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of László Bartosiewicz.
Márta Daróczi-Szabó
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Roman Age iron tools from Pannonia

Dissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2016
of PhD thesis submitted in 2015 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of László Borhy.
László Rupnik
doaj   +1 more source

Junior doctor led teaching programme provides insight for incoming Foundation doctors [PDF]

Medical Teacher, 2015
Dear SirAfter passing final examinations, graduation from medical school is thought to be a time to celebrate, however, most view it as the calm before the storm with students finding the transitio...
Oliver J, Ziff, Monica, Samra
openaire   +2 more sources