Results 41 to 50 of about 30,654 (263)

Roman Age iron tools from Pannonia

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2016
of PhD thesis submitted in 2015 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of László Borhy.
László Rupnik
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Transformations of the human communities in the eastern part of the Carpathian Basin between the middle of the 5th and 7th century

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2019
of PhD thesis submitted in 2018 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of Tivadar Vida.
Alpár Dobos
doaj   +1 more source

Complex, household-based analysis of the stone tools of Polgár-Csőszhalom

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2020
of PhD thesis submitted in 2019 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of Pál Raczky and Zsolt Mester.
Norbert Faragó
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Late groups of the Alföld Linear Pottery culture in north-eastern Hungary. New results of the research in Borsod-Abaúj-Zemplén County

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2015
of PhD thesis submitted in 2014 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of Pál Raczky.
Piroska Csengeri
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

‘...circa Danubium...’ from the Late Avar Age until the Early Árpádian Age: 8th–11th-Century Settlements in the Region of the Central Part of the Hungarian Little Plain and the Danube Bend

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae, 2020
and further consideration of the PhD thesis submitted in the winter of 2018 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of Miklós Takács.
Szabina Merva
doaj   +1 more source

Programme doctoral « Études méditerranéennes » 2022-2023

open access: yesSociétés en mutation en Méditerranée, 2023
L’Institut Sociétés en Mutation en Méditerranée (SoMuM) propose une offre de formation accessible aux doctorants appartenant aux écoles doctorales « Espaces, Cultures, Sociétés » (ED 355), « Sciences juridiques et politiques » (ED 67), « Langues, Lettres et Art (ED 354) d’Aix-Marseille Université, et rattachées aux douze laboratoires du périmètre de l ...
openaire   +2 more sources

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