Results 91 to 100 of about 16,255,401 (402)

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

MIDV-500: a dataset for identity document analysis and recognition on mobile devices in video stream [PDF]

open access: yesКомпьютерная оптика, 2019
A lot of research has been devoted to identity documents analysis and recognition on mobile devices. However, no publicly available datasets designed for this particular problem currently exist.
Vladimir Arlazarov   +3 more
doaj   +1 more source

Towards identifying and minimizing customer-facing documentation debt [PDF]

open access: yes
Software documentation often struggles to catch up with the pace of software evolution. The lack of correct, complete, and up-to-date documentation results in an increasing number of documentation defects which could introduce delays in integrating software systems.
arxiv   +1 more source

Assembling and enriching digital library collections [PDF]

open access: yes, 2003
People who create digital libraries need to gather together the raw material, add metadata as necessary, and design and build new collections. This paper sets out the requirements for these tasks and describes a new tool that supports them interactively,
Bainbridge, David   +2 more
core   +2 more sources

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

DOCUMENT COMMUNICATION AS A FORM OF SOCIAL COMMUNICATION

open access: yesVestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 2. Âzykoznanie, 2014
The article considers the notion of document communication in its relation to the notions of communication and social communication. The author analyses the approaches to the classification of communication types, to identification of its components ...
Saidgasanova Elnara Umalatovna
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Exploring Multi-Tasking Learning in Document Attribute Classification [PDF]

open access: yesarXiv, 2021
In this work, we adhere to explore a Multi-Tasking learning (MTL) based network to perform document attribute classification such as the font type, font size, font emphasis and scanning resolution classification of a document image. To accomplish these tasks, we operate on either segmented word level or on uniformed size patches randomly cropped out of
arxiv  

A Typed Calculus for Querying Distributed XML Documents [PDF]

open access: yes, 2007
We study the problems related to querying large, distributed XML documents. Our proposal takes the form of a new process calculus in which XML data are processes that can be queried by means of concurrent pattern-matching expressions. What we achieve is a functional, strongly-typed programming model based on three main ingredients: an asynchronous ...
ACCIAI, LUCIA   +2 more
openaire   +4 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

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