Results 81 to 90 of about 734,031 (297)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Others and My Image: Debate on Indigenous Representation with Martu and Pankararu Filmmakers

open access: yeseTropic: electronic journal of studies in the tropics, 2015
What interests us in this paper is to explore some issues related to the genre of documentary that we usually call the "ethnographic film" focused on the experience of two indigenous filmmakers on a residence project during the 5th International ...
Renato Athias
doaj   +1 more source

Ending the silence : a documentary theatre response to the impact of German war guilt on intergenerational, bi-cultural identity in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University, Albany, New Zealand [PDF]

open access: yes, 2016
This exegesis forms the written accompaniment to the documentary theatre production Ending the Silence. Together, these creative and critical components form the basis for a Performance as Research (PAR) project undertaken as part of a Masters in English
Hines, Rebekah Leigh
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Raymond Depardon Sinemasında Etik Kaygılar

open access: yesİletişim Kuram ve Araştırma Dergisi
İçinde yaşadığımız dünyanın temsilini sunan belgeseller toplumsal katılımcılar diye adlandırdığımız gerçek kişilerin yaşamlarından, deneyimledikleri olay ve durumlar hakkında kesitler sunarken onların çıkarlarını da korumak durumundadır.
Merve Gezen
doaj   +1 more source

Mercy [PDF]

open access: yes, 2003
Includes bibliographical references.The way in which indigenous people are represented in documentaries has radically changed within the last century. But "If there (still) is one overriding ethical/political / ideological!
Hibbeler, Christian
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Discovering Arab Indianapolis: An Interview with Edward Curtis IV

open access: yesMashriq & Mahjar
In Arab Indianapolis: A Hidden History, author and historian Edward E. Curtis IV explores the origins and growth of the Arab American community in Indianapolis, Indiana.
Edward Curtis IV, Lindsey Waldenberg
doaj   +1 more source

REVIEW: Noted: Documentary exposes dark side of Tongan diaspora

open access: yesPacific Journalism Review, 2019
Gangsters in Paradise—The Deportees of Tonga. Documentary. 2019. Director: Ursula Williams. Vice/Zealandia. ‘IT’S LIKE crabs being stuck in a bucket scratching each other to get out.’ ‘It’s like rubbish dumping.’ Those are two views about the crisis ...
Philip Cass
doaj   +1 more source

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