Results 11 to 20 of about 533 (104)

Recent advances in surface plasmon resonance as a powerful approach for studying Leishmania spp. and Trypanosoma cruzi parasites

Talanta Open, 2023
Leishmaniases and Chagas disease pose significant health challenges, particularly in tropical regions among impoverished communities. These conditions prevail in areas characterized by limited resources and have necessitated the continuous development of
Fatemeh Farshchi, Geovane Dias-Lopes, Luzia Monteiro Castro-Côrtes, Carlos Roberto Alves, Franklin Souza-Silva   +4 more
doaj   +1 more source

HISTOPLASMOSE CUTÂNEA EXTENSA ASSOCIADA À PÊNFIGO VULGAR EM PACIENTE IMUNOCOMPETENTE

Brazilian Journal of Infectious Diseases, 2023
A histoplasmose, causada pelo fungo Histoplasma capsulatum, é uma micose endêmica que eventualmente pode resultar em doença grave. A maioria dos pacientes que desenvolve histoplasmose severa é imunodeprimida ou está em extremos de idade.
Roberta Lestch da Silveira, Jerusa Marquardt Corazza, Fernanda Caldeira Veloso dos Santos, Thami Ellen Busanello Spanevello, Adriane Schio Pagliarini   +4 more
doaj   +1 more source

Detection of Metalloproteases and Cysteine Proteases RNA Transcripts of Leishmania (Leishmania) infantum in Ear Edge Skin of Naturally Infected Dogs

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
Leishmania spp. proteases have been proposed as virulence factors contributing to adaptive success these parasites to the mammalian hosts. Since these enzymes are poorly studied in naturally infected dogs, this work aims to show the differences in metalloprotease and cysteine proteases gene expression in ear edge skin of dogs naturally infected by ...
Laura Barral Veloso, Flávia de Oliveira Cardoso, Karen dos Santos Charret, Matheus Pereira de Sá Silva, Luzia Monteiro de Castro Côrtes, Kátia da Silva Calabrese, Franklin Souza da Silva, Joel Fontes de Sousa, Marília Fonseca Rocha, Carlos Roberto Alves, Mansour El-Matbouli   +10 more
wiley   +1 more source

Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony

Scientific Reports, 2021
Glucantime (SbV) is the first-line treatment against American Tegumentary Leishmaniasis. Resistance cases to this drug have been reported and related to host characteristics and parasite phenotypes.
Anabel Zabala-Peñafiel, Geovane Dias-Lopes, Léa Cysne-Finkelstein, Fátima Conceição-Silva, Luciana de Freitas Campos Miranda, Aline Fagundes, Armando de Oliveira Schubach, Maria Inês Fernandes Pimentel, Franklin Souza-Silva, Lucas de Almeida Machado, Carlos Roberto Alves   +10 more
doaj   +1 more source

Reactivity of sera from dogs living in a leishmaniasis-endemic area to the COOH-terminal region of cysteine proteinase B

Brazilian Journal of Infectious Diseases, 2020
Cysteine proteinases are well-known virulence factors of Leishmania spp. with demonstrated actions in both experimental mouse infection and human infection. However, studies on these enzymes in canine leishmaniasis are scarce.
Laura Barral-Veloso, Barbara Cristina de Albuquerque Melo, Raquel Santos-de-Souza, Léa Cysne-Finkelstein, Franklin Souza-Silva, Fernanda Nunes Santos, Joel Fontes de Sousa, Carlos Roberto Alves   +7 more
doaj   +1 more source

Overview of the organization of protease genes in the genome of Leishmania spp

Parasites & Vectors, 2014
Background The genus Leishmania includes protozoan parasites that are able to infect an array of phlebotomine and vertebrate species. Proteases are related to the capacity of these parasites to infect and survive in their hosts and are therefore ...
Mariana Silva-Almeida, Franklin Souza-Silva, Bernardo Acácio Santini Pereira, Michelle Lopes Ribeiro-Guimarães, Carlos Roberto Alves   +4 more
doaj   +1 more source

The midgut of Aedes albopictus females expresses active trypsin-like serine peptidases

Parasites & Vectors, 2014
Background Aedes albopictus is widely distributed across tropical and sub-tropical regions and is associated with the transmission of several arboviruses.
Leonardo Saboia-Vahia, Patricia Cuervo, Andre Borges-Veloso, Nathália Pinho de Souza, Constança Britto, Geovane Dias-Lopes, Jose Batista De Jesus   +6 more
doaj   +1 more source

Development of conventional and real-time multiplex PCR-based assays for estimation of natural infection rates and Trypanosoma cruzi load in triatomine vectors

Parasites & Vectors, 2017
Background Chagas disease is a complex anthropozoonosis with distinct domestic and sylvatic mammal species acting as potential reservoirs. The diversity of vector species and their habitats are among the factors that hinder the control of the disease ...
Otacilio C. Moreira, Thaiane Verly, Paula Finamore-Araujo, Suzete A. O. Gomes, Catarina M. Lopes, Danielle M. de Sousa, Lívia R. Azevedo, Fabio F. da Mota, Claudia M. d’Avila-Levy, Jacenir R. Santos-Mallet, Constança Britto   +10 more
doaj   +1 more source

Principais ameaças sanitárias endêmicas da cadeia produtiva de suínos no Brasil [PDF]

Pesquisa Agropecuária Brasileira, 2016
Resumo: O Brasil se destaca por ser o quarto maior produtor e exportador de carne suína. A ocorrência de determinadas doenças na produção animal é um dos fatores mais importantes para a suinocultura.
Janice Reis Ciacci Zanella, Nelson Morés, David Emilio Santos Neves de Barcellos   +2 more
doaj   +1 more source

Novel Insights Into Leishmania (Viannia) braziliensis In Vitro Fitness Guided by Temperature Changes Along With Its Subtilisins and Oligopeptidase B

Frontiers in Cellular and Infection Microbiology, 2022
Proteases are virulence factors with a recognized impact on the Leishmania spp. life cycle. This study considers a set of analyses measuring phenotypic factors of L.
Anabel Zabala-Peñafiel, Lea Cysne-Finkelstein, Fatima Conceição-Silva, Aline Fagundes, Luciana de Freitas Campos Miranda, Franklin Souza-Silva, Franklin Souza-Silva, Artur A. M. L. Brandt, Artur A. M. L. Brandt, Geovane Dias-Lopes, Carlos Roberto Alves   +10 more
doaj   +1 more source