Results 91 to 100 of about 1,250,382 (359)

Fleece-Lined Whelping Pools Associated with Reduced Incidence of Canine Hip Dysplasia in a Guide Dog Program

Animals
Using genetic selection, Guide Dogs for the Blind (GDB) has reduced the incidence rate of canine hip dysplasia (CHD). However, given that CHD is polygenic and multifactorial, environmental factors may impact the expression of this developmental condition.
Lynna C. Feng, Alexandra Philippine, Elizabeth Ball-Conley, Sarah-Elizabeth Byosiere   +3 more
doaj   +1 more source

The detection of capsaicin and dihydrocapsaicin in horse serum following long-term local administration

BMC Veterinary Research, 2018
Background Capsaicin and dihydrocapsaicin are alkaloids with analgesic effects in humans and animals. When used locally, both of them minimalise pain sensation by defunctionalising nerve endings.
A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, P. Szpot, M. Zawadzki, A. Niedzwiedz   +6 more
doaj   +1 more source

Safety and pharmacokinetics of thalidomide in tumor-bearing dogs

, 2023
Fukiko Matsuyama, Yukiyoshi FUJITA, Eri Fukazawa, T. Kobayashi   +3 more
openalex   +2 more sources

Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias. [PDF]

, 2018
BackgroundSotalol is a commonly used antiarrhythmic drug that may alter ventricular function.ObjectiveTo determine the effect of sotalol on echocardiographic indices of ventricular systolic function in dogs with ventricular arrhythmias.AnimalsThirty-five
Anderson, Baumwart, Chetboul, Cornell, Dukes-McEwan, Hansson, Hoffmann, Hohnloser, Kaye, Mahmarian, Maran, Martin, Meurs, Meurs, Meurs, Meurs, Motskula, Oyama, Palermo, Peralta, Schnelle, Seidler, Singh, Smets, Stephenson, Summerfield, Visser, Visser, Wess, Wess, Zupan   +30 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Why do dogs (Canis familiaris) select the empty container in an observational learning task? [PDF]

, 2011
Many argue that dogs show unique susceptibility to human communicative signals that make them suitable for being engaged in complex co-operation with humans.
A Cleveland, A Dijksterhuis, A Senju, A Senju, AN Meltzoff, B Hare, B Hare, C Schwier, C Tennie, C Teuscher, D Buttelmann, D Buttelmann, F Range, F Range, F Range, F Warneken, G Csibra, G Gergely, G Gergely, G Gergely, György Gergely, H Bekkering, H Moll, H Moll, HC Miller, I Király, J Bräuer, J Kaminski, J Riedel, J Topál, J Topál, J Topál, J Topál, J Topál, J Topál, JMD Yoon, József Topál, Krisztina Kupán, M Carpenter, M Carpenter, M Gácsi, M Gácsi, M Nielsen, M Tomasello, M Tomasello, M Tomasello, MJ Rochat, N Wood, P Pongrácz, P Prato-Previde, P Ricciardelli, PJ Reid, T Grossmann, V Horner, V Szetei, Zs Virányi, Á Erdőhegyi, Á Miklósi, Ádám Miklósi   +58 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Temporal Changes in Indicators of Testicular Dysgenesis Syndrome in Labrador and Golden Retrievers

Animals
Temporal changes in testicular traits have been reported in both humans and dogs. Analysis of % living sperm and motility from semen collections from 186 Labrador Retrievers and 113 Golden Retrievers between 2006 and 2023, and of incidents of ...
Thomas Lewis, Rachel Moxon, Gary C. W. England   +2 more
doaj   +1 more source

A liver core needle biopsy technique in guinea pigs (Cavia porcellus)

Acta Veterinaria Scandinavica, 2019
The aim of this study was to describe a core needle biopsy technique in the guinea pig (Cavia porcellus) and to assess the incidence of complications when applying this method.
Kamila Glińska-Suchocka, Marcin Jankowski, Krzysztof Kubiak, Jolanta Spużak, Pola Borusewicz, Dominika Kubiak-Nowak   +5 more
doaj   +1 more source

The effect of Eck and reverse Eck fistula in dogs with experimental diabetes mellitus [PDF]

, 1959
1. 1. Dogs with alloxan diabetes were subjected to Eck fistula. This procedure produced a marked increase in the amount of insulin necessary to control glycosuria.
Meyer, WH, Starzl, TE
core