Results 41 to 50 of about 71,900 (266)

JAMOOS - A Domain-Specific Language for Language Processing

open access: yesJournal of Computing and Information Technology, 2001
Summary: JAMOOS is a cohesive suite for quick definition of attribute grammars and generation of compilers, interpreters and other language processing tools. As a programming language, JAMOOS brings a new tree computing metaphor which unifies the notions of object creation, procedure call and reduction of rules in an attribute context-free grammar ...
Gil, Joseph, Tsoglin, Yuri
openaire   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Domain-specific markup languages and descriptive metadata: their functions in scientific resource discovery

open access: yesEncontros Bibli, 2010
While metadata has been a strong focus within information professionals’ publications, projects, and initiatives during the last two decades, a significant number of domain-specific markup languages have also been developing on a parallel path at the ...
Marcia Lei Zeng
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Wodel-Test: A model-based framework for engineering language-specific mutation testing tools

open access: yesSoftwareX
Mutation testing (MuT) is a well-known technique for assessing the quality of software test suites. It relies on the artificial injection of errors into the source code, which results in a collection of variations called mutants.
Pablo Gómez-Abajo   +2 more
doaj   +1 more source

Code generation approaches for parallel geometric multigrid solvers

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020
Software development for applications in computational science and engineering has become complex in recent years. This is mainly due to the increasing parallelism and heterogeneity in modern computer architectures and to the more realistic physical and ...
Köstler Harald   +5 more
doaj   +1 more source

Digital Activities in Teaching/Learning a Foreign Language for Specific Purposes, Technical/Scientific Domain [PDF]

open access: yesJournal of Humanistic and Social Studies, 2021
The present pandemic has determined the teachers to adopt new methods of on-line teaching and learning and the specific activities within the classes of foreign languages for special purposes, technical and scientific domain are part of these new ...
Cristina Ana Măluţan, Monica Negoescu
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Iterative Evaluation Of Domain-Specific Languages [PDF]

open access: yes, 2013
As software moves to the daily routines and responsibilities of people, there is a need for developing tools and languages rapidly. Domain-Specific Languages (DSLs) are claimed to contribute to this productivity increase, while reducing the required maintenance and programming expertise.
openaire   +3 more sources

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