Results 101 to 110 of about 2,381,020 (313)

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes

Theranostics, 2011
The long-term objective of this project is to utilize the I-domain protein for the α-subunit of LFA-1 to target drugs to lymphocytes by binding to ICAM receptors on the cell surface.
Prakash Manikwar, Bimo A. Tejo, Heather Shinogle, David S. Moore, Tahl Zimmerman, Francisco Blanco, Teruna J. Siahaan
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Localized direct segregated boundary-domain integral equations for variable-coefficient transmission problems with interface crack [PDF]

, 2011
The full text of the published article can be accessed at the link belowSome transmission problems for scalar second order elliptic partial differential equations are considered in a bounded composite domain consisting of adjacent anisotropic subdomains ...
Mikhailov, SE, Natroshvili, D, Chkadua, O   +2 more
core  

Configurational anisotropy in single-domain and pseudosingle-domain grains of magnetite [PDF]

, 2006
In classical domain theory, single-domain (SD) grains change their magnetization by coherent rotation, where the energy barrier to domain reversal is provided by the magnetocrystalline anisotropy or by shape anisotropy for elongated grains.
Paterson, GA, Williams, W., Paterson, G.A., Muxworthy, A., Paterson, Greig A., Muxworthy, AR, Williams, W, Williams, Wyn; id_orcid, Muxworthy, Adrian R.   +8 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Numerical Computation of 2D Domain Integrals in Boundary Element Method by (α, β) Distance Transformation for Transient Heat Conduction Problems

Axioms
When the time-dependent boundary element method, also termed the pseudo-initial condition method, is employed for solving transient heat conduction problems, the numerical evaluation of domain integrals is necessitated.
Yunqiao Dong, Zhengxu Tan, Hengbo Sun
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source