Conformational stability analyses of alpha subunit I domain of LFA-1 and Mac-1. [PDF]
β₂ integrin of lymphocyte function-associated antigen-1 (LFA-1) or macrophage-1 antigen (Mac-1) binds to their common ligand of intercellular adhesion molecule-1 (ICAM-1) and mediates leukocyte-endothelial cell (EC) adhesions in inflammation cascade ...
Debin Mao +4 more
doaj +3 more sources
Crystal structure of the α1β1 integrin I‐domain: insights into integrin I‐domain function [PDF]
The α1β1 integrin is a major cell surface receptor for collagen. Ligand binding is mediated, in part, through a ∼200 amino acid inserted ‘I’‐domain contained in the extracellular part of the integrin α chain. Integrin I‐domains contain a divalent cation binding (MIDAS) site and require cations to interact with integrin ligands.
Nolte, Matthias +5 more
openaire +2 more sources
Platelet integrin α 2 I-domain specific antibodies produced via domain specific DNA vaccination combined with variable gene phage display [PDF]
Antibodies are a powerful tool for structure/function studies of platelet proteins. However, classic immunisation frequently elicits antibody responses against domains of minor functional interest. Robust strategies to generate antibodies against defined
Deckmyn, H. +17 more
core +1 more source
De Novo Polycomb Recruitment and Repressive Domain Formation
Every cell of an organism shares the same genome; even so, each cellular lineage owns a different transcriptome and proteome. The Polycomb group proteins (PcG) are essential regulators of gene repression patterning during development and homeostasis ...
Itzel Alejandra Hernández-Romero +1 more
doaj +1 more source
Domain mismatch modeling of out-domain i-vectors for PLDA speaker verification [PDF]
The state-of-the-art i-vector based probabilistic linear discriminant analysis (PLDA) trained on non-target (or out- domain) data significantly affects the speaker verification performance due to the domain mismatch between training and evaluation data ...
Dean, David +7 more
core +1 more source
Antimicrobial effect of probiotics on bacterial species from dental plaque
Introduction: The antimicrobial role of probiotic Lactobacillus casei subspecies casei DG (L. casei DG) and of the mix culture of probiotic Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 was tested on species of Staphylococcus, Streptococcus ...
Csilla Zambori +6 more
doaj +1 more source
Unsupervised Domain Adaptive Corner Detection in Vehicle Plate Images
Rectification of vehicle plate images helps to improve the accuracy of license-plate recognition (LPR). It is a perspective-transformation process to project images as if taken from the front geometrically. To obtain the projection matrix, we require the
Kyungkoo Jun
doaj +1 more source
Sectional domain specific languages [PDF]
Nowadays, many problems are solved by using a domain specific language (DSL), i.e., a programming language tailored to work on a particular application domain.
W. Cazzola +3 more
core +1 more source
Armillaria sp. 541, a genus of root-infecting fungi, forms a symbiosis with traditional Chinese medicine Gastrodia elata (Orchid) and Polyporus umbellatus via extensive networks of durable rhizomorphs.
Bing Li +3 more
doaj +1 more source
Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy. [PDF]
Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known.
Kellermayer Miklós +5 more
core +1 more source

