Results 51 to 60 of about 2,381,020 (313)

Apicortin, a Putative Apicomplexan-Specific Protein, Is Present in Deep-Branching Opisthokonts

Biology
Apicortin, a tubulin/microtubule-binding protein, was first described in 2009 as a protein characteristic of apicomplexans; it was found to be present in all Apicomplexa genomes already sequenced.
Ferenc Orosz
doaj   +1 more source

In vitro reconstitution of chromatin domains

, 2023
ABSTRACT The spatial organization of the genome modulates nuclear processes, including transcription, replication, and DNA repair 1,2 . Eukaryotic genomes are organized into distinct 3D chromatin domains 3 .
Quililan, Kimberly, Oberbeckmann, Elisa, Cramer, Patrick, Oudelaar, A. Marieke   +3 more
openaire   +2 more sources

The phosphoCTD-interacting domain of Topoisomerase I [PDF]

Biochemical and Biophysical Research Communications, 2010
The N-terminal domain (NTD) of Drosophila melanogaster (Dm) Topoisomerase I has been shown to bind to RNA polymerase II, but the domain of RNAPII with which it interacts is not known. Using bacterially-expressed fusion proteins carrying all or half of the NTDs of Dm and human (Homo sapiens, Hs) Topo I, we demonstrate that the N-terminal half of each ...
Jianhong, Wu, Hemali P, Phatnani, Tao-Shih, Hsieh, Arno L, Greenleaf   +3 more
openaire   +2 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

An Idempotent-Based Generalization of Semicommutative Rings

Mathematics
We introduce and study several new classes of rings defined by idempotent conditions. A ring R is called i-semicommutative if (1−ab)aRb(1−ab)=0 whenever ab is a nonzero idempotent. This property lies strictly between semicommutativity and i-reversibility
Muhammad Saad, Majed Zailaee
doaj   +1 more source

Biochemical Characterizations of the Putative Endolysin Ecd09610 Catalytic Domain from Clostridioides difficile

Antibiotics, 2022
Clostridioides difficile is the major pathogen of pseudomembranous colitis, and novel antimicrobial agents are sought after for its treatment. Phage-derived endolysins with species-specific lytic activity have potential as novel antimicrobial agents.
Hiroshi Sekiya, Hina Yamaji, Ayumi Yoshida, Risa Matsunami, Shigehiro Kamitori, Eiji Tamai   +5 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

An activating mutation reveals a second binding mode of the integrin α2 I domain to the GFOGER motif in collagens.

PLoS ONE, 2013
The GFOGER motif in collagens (O denotes hydroxyproline) represents a high-affinity binding site for all collagen-binding integrins. Other GxOGER motifs require integrin activation for maximal binding.
Federico Carafoli, Samir W Hamaia, Dominique Bihan, Erhard Hohenester, Richard W Farndale   +4 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Influence of Humidity on the Domain-Structure Evolution During Local Switching in a (100) Cut Bi₄Ti₃O₁₂ Single Crystal

Crystals
The formation and growth of isolated domains during local switching by a biased tip of a scanning probe microscope in a (100) cut of a bismuth titanate Bi4Ti3O12 single crystal were studied experimentally.
Anton Turygin, Mikhail Kosobokov, Semion Melnikov, Vladimir Shur   +3 more
doaj   +1 more source