Results 111 to 120 of about 4,193,737 (302)

Nucleon structure from 2+1-flavor domain-wall QCD

, 2017
Nucleon-structure calculations of isovector vector- and axialvector-current form factors, transversity and scalar charge, and quark momentum and helicity fractions are reported from two recent 2+1-flavor dynamical domain-wall fermions lattice-QCD ...
Ohta, Shigemi
core   +2 more sources

Domain structure and domain-domain interactions of recombinant tissue plasminogen activator

Journal of Biological Chemistry, 1991
The melting of recombinant tissue plasminogen activator (rtPA) has been investigated by differential scanning calorimetry and fluorescence spectroscopy. At neutral pH, rtPA melts with only partial reversibility in a single sharp peak that can be deconvoluted into four transitions.
V V, Novokhatny, K C, Ingham, L V, Medved   +2 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Nucleon structure with two flavors of dynamical domain-wall fermions

, 2008
We present a numerical lattice quantum chromodynamics calculation of isovector form factors and the first few moments of the isovector structure functions of the nucleon.
E. G. Floratos, H.-W. Lin, Huey-Wen Lin, K. Orginos, M. Gockeler, P. Hagler, R. G. Edwards, S. Syritsyn, Shigemi Ohta, Shoichi Sasaki, T. Yamazaki, Takeshi Yamazaki, Tom Blum   +12 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

DOMAIN CONTRIBUTION TO THE DIELECTRIC PROPERTIES OF THE CRYSTALS OF TRIGLYCINE SULPHATE GROUP AND ROCHELLE SALT

Конденсированные среды и межфазные границы, 2017
The dielectric properties of the crystals of nominally pure triglycine sulphate (TGS), deuterated TGS, TGS doped with L,α – alanine, TGS with impurity of phosphorus P5+ ions, TGS subjected to X-ray radiation as well as of Rochelle salt crystal were ...
Golitsyna Olga M., Drozhdin Sergey N., Chulakova Valeriya O. , Gridnev Aleksandr E.   +3 more
doaj   +1 more source

Field sweep rate dependence of magnetic domain patterns: Numerical simulations for a simple Ising-like model

, 2007
We study magnetic domain patterns in ferromagnetic thin films by numerical simulations for a simple Ising-like model. Magnetic domain patterns after quench demonstrate various types of patterns depending on the field sweep rate and parameters of the ...
Katsuhiro Nakamura, Kazue Kudo, M. Mino
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source