Results 11 to 20 of about 83,637 (272)
3D domain swapping: As domains continue to swap [PDF]
Protein Science, 2002 Abstract Three‐dimensional (3D) domain swapping creates a bond between two or more protein molecules as they exchange their identical domains. Since the term '3D domain swapping' was first used to describe the dimeric structure of diphtheria toxin, the database of domain‐swapped proteins has greatly expanded. Analyses of the now about
Yanshun, Liu, David, Eisenberg
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Domain swapping and amyloid fibril conformation [PDF]
Prion, 2012 For several different proteins an apparent correlation has been observed between the propensity for dimerization by domain-swapping and the ability to aggregate into amyloid-like fibrils.
Van Der Wel, PCA
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Deposition Diseases and 3D Domain Swapping [PDF]
Structure, 2006 Protein aggregation is a feature of both normal cellular assemblies and pathological protein depositions. Although the limited order of aggregates has often impeded their structural characterization, 3D domain swapping has been implicated in the formation of several protein aggregates.
Bennett, Melanie J. +2 more
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Domain swapping in allosteric modulation of DNA specificity.
PLoS Biology, 2010 SgrAI is a type IIF restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of cleavage activity and sequence specificity.
Chad K Park +7 more
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3D domain swapping: A mechanism for oligomer assembly [PDF]
Protein Science, 1995 Abstract3D domain swapping is a mechanism for forming oligomeric proteins from their monomers. In 3D domain swapping, one domain of a monomeric protein is replaced by the same domain from an identical protein chain. The result is an intertwined dimer or higher oligomer, with one domain of each subunit replaced by the identical domain from another ...
M J, Bennett +2 more
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Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites. [PDF]
Proc Natl Acad Sci U S A, 2021 Beitia GJ +5 more
europepmc +2 more sources
Domain Swapping and Retroviral Assembly [PDF]
Molecular Cell, 2005 The structure of a mammalian SCAN domain has been recently reported. The molecule is a structural homolog of the HIV-1 capsid protein and forms a domain-swapped dimer in solution. The authors propose a similar domain-swapping event facilitates HIV-1 assembly, providing a new model for protein-protein interactions underlying viral particle formation.
Kingston, Richard L., Vogt, Volker M.
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Topological Determinants of Protein Domain Swapping [PDF]
Structure, 2006 Protein domain swapping has been repeatedly observed in a variety of proteins and is believed to result from destabilization due to mutations or changes in environment. Based on results from our studies and others, we propose that structures of the domain-swapped proteins are mainly determined by their native topologies. We performed molecular dynamics
Ding, Feng +3 more
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Unraveling the Functional Significance of Unstructured Regions in G Protein-Coupled Receptors
Biomolecules, 2023 Unstructured regions in functional proteins have gained attention in recent years due to advancements in informatics tools and biophysical methods.
Roberto Maggio +5 more
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Dramatic structural changes resulting from the loss of a crucial hydrogen bond in the hinge region involved in C-terminal helix swapping in SurE: a survival protein from Salmonella typhimurium. [PDF]
PLoS ONE, 2013 Domain swapping is an interesting feature of some oligomeric proteins in which each protomer of the oligomer provides an identical surface for exclusive interaction with a segment or domain belonging to another protomer.
Yamuna Kalyani Mathiharan +3 more
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