Results 41 to 50 of about 1,858,101 (277)
Genome-Wide Analysis of Domain-Swap Predicted Products in the Genome of Anti-Stress Medicinal Plant:
Bioinformatics and Biology Insights, 2019 Computational approaches to high-throughput data are gaining importance because of explosion of sequences in the post-genomic era. This explosion of sequence data creates a huge gap among the domains of sequence structure and function, since the ...
Atul Kumar Upadhyay +1 more
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The Making of a Slicer: Activation of Human Argonaute-1
Cell Reports, 2013 Argonautes are the central protein component in small RNA silencing pathways. Of the four human Argonautes (hAgo1–hAgo4) only hAgo2 is an active slicer.
Christopher R. Faehnle +4 more
doaj +1 more source
3DSwap: Curated knowledgebase of proteins involved in 3D domain swapping [PDF]
, 2011 Three-dimensional domain swapping is a unique protein structural phenomenon where two or more protein chains in a protein oligomer share a common structural segment between individual chains.
S. C. P. Manjunath +12 more
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Linking in domain-swapped protein dimers
Scientific Reports, 2016 AbstractThe presence of knots has been observed in a small fraction of single-domain proteins and related to their thermodynamic and kinetic properties. The exchanging of identical structural elements, typical of domain-swapped proteins, makes such dimers suitable candidates to validate the possibility that mutual entanglement between chains may play a
Marco Baiesi +3 more
openaire +3 more sources
Probing the mechanism of 3D-domain swapping [PDF]
, 2011 Domain swapping, the process in which a structural unit is exchanged between monomers to create a dimer containing two versions of the monomeric fold, is believed to be an important mechanism for oligomerization and the formation of amyloid fibrils. Very
Miller, Katherine Helen
core +1 more source
Domain-swapping analyses of ICR-Mo.
, 2018 A. Schematic illustration for domain-swapping designing amongst the three transmembrane enzymes EptA, MCR-1 and ICR-Mo (AXE82_07515). B. Use of Western blotting to detect the expression of icr-Mo and its mosaic versions. C.
Swaminath Srinivas (450675) +7 more
core +1 more source
The Evolving Role of 3D Domain Swapping in Proteins [PDF]
, 2004 3D domain swapping is increasingly implicated in amyloidosis but also has potential functional advantages in soluble proteins. Indeed, the structure of an NF-κB p50 mutant (Chirgadze et al., 2004) demonstrates that 3D domain swapping can rescue function ...
Bennett, Melanie J, Eisenberg, David
core +1 more source
Data swapping for protecting census tables [PDF]
, 2010 The pre-tabular statistical disclosure control (SDC) method of data swapping is the preferred method for protecting Census tabular data in some National Statistical Institutes, including the United States and Great Britain.
Tudor, Caroline +2 more
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Deciphering MCR-2 Colistin Resistance
mBio, 2017 Antibiotic resistance is a prevalent problem in public health worldwide. In general, the carbapenem β-lactam antibiotics are considered a final resort against lethal infections by multidrug-resistant bacteria.
Jian Sun +11 more
doaj +1 more source
Crystal structure of domain‐swapped STE20 OSR1 kinase domain [PDF]
Protein Science, 2009 AbstractOSR1 (oxidative stress‐responsive‐1) and SPAK (Ste20/Sps1‐related proline/alanine‐rich kinase) belong to the GCK‐VI subfamily of Ste20 group kinases. OSR1 and SPAK are key regulators of NKCCs (Na+/K+/2Cl− cotransporters) and activated by WNK family members (with‐no‐lysine kinase), mutations of which are known to cause Gordon syndrome, an ...
Seung-Jae, Lee +2 more
openaire +2 more sources