Results 31 to 40 of about 83,637 (272)
Trimeric domain-swapped barnase
Proceedings of the National Academy of Sciences, 1999 The structure of a trimeric domain-swapped form of barnase (EC 3.1.27.3 ) was determined by x-ray crystallography at a resolution of 2.2 Å from crystals of space group R 32. Residues 1–36 of one molecule associate with residues 41–110 from another molecule related through threefold symmetry ...
Zegers, Nathalie +2 more
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Crystal structure of domain‐swapped STE20 OSR1 kinase domain [PDF]
Protein Science, 2009 AbstractOSR1 (oxidative stress‐responsive‐1) and SPAK (Ste20/Sps1‐related proline/alanine‐rich kinase) belong to the GCK‐VI subfamily of Ste20 group kinases. OSR1 and SPAK are key regulators of NKCCs (Na+/K+/2Cl− cotransporters) and activated by WNK family members (with‐no‐lysine kinase), mutations of which are known to cause Gordon syndrome, an ...
Seung-Jae, Lee +2 more
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Parallel implementation of an optimal two level additive Schwarz preconditioner for the 3-D finite element solution of elliptic partial differential equations [PDF]
, 2002 This paper presents a description of the extension and parallel implementation of a new two level additive Schwarz (AS) preconditioner for the solution of 3-D elliptic partial differential equations (PDEs). This preconditioner, introduced in Bank et al. (
Ashby +13 more
core +2 more sources
Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol Cell, 2016 Gammons MV +4 more
europepmc +2 more sources
Laser frequency combs and ultracold neutrons to probe braneworlds through induced matter swapping between branes [PDF]
, 2011 This paper investigates a new experimental framework to test the braneworld hypothesis. Recent theoretical results have shown the possibility of matter exchange between branes under the influence of suitable magnetic vector potentials.
Fabrice Petit +3 more
core +2 more sources
Domain-swapping of mesophilic xylanase with hyper-thermophilic glucanase
BMC Biotechnology, 2012 Background Domain fusion is limited at enzyme one terminus. The issue was explored by swapping a mesophilic Aspergillus niger GH11 xylanase (Xyn) with a hyper-thermophilic Thermotoga maritima glucanase (Glu) to construct two chimeras, Xyn-Glu and Glu-Xyn,
Liu Liangwei +5 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2022 Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids (Sia) from sialoglycoconjugates to terminal galactose or N-acetylgalactosamine residues of oligosaccharides without the ...
Mario Waespy +6 more
doaj +1 more source
Linking in domain-swapped protein dimers
Scientific Reports, 2016 AbstractThe presence of knots has been observed in a small fraction of single-domain proteins and related to their thermodynamic and kinetic properties. The exchanging of identical structural elements, typical of domain-swapped proteins, makes such dimers suitable candidates to validate the possibility that mutual entanglement between chains may play a
Marco Baiesi +3 more
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Molecular Therapy: Methods & Clinical Development, 2022 Recent clinical successes have intensified interest in using adeno-associated virus (AAV) vectors for therapeutic gene delivery. The liver is a key clinical target, given its critical physiological functions and involvement in a wide range of genetic ...
Marti Cabanes-Creus +14 more
doaj +1 more source
The Unfolding Story of Three-Dimensional Domain Swapping [PDF]
Structure, 2003 Three-dimensional domain swapping is the event by which a monomer exchanges part of its structure with identical monomers to form an oligomer where each subunit has a similar structure to the monomer. The accumulating number of observations of this phenomenon in crystal structures has prompted speculation as to its biological relevance. Domain swapping
Rousseau, Frederic +2 more
openaire +3 more sources