Results 31 to 40 of about 1,858,101 (277)
Synthetic and Systems Biotechnology, 2020 Modular polyketide synthases (PKSs) are a multidomain megasynthase class of biosynthetic enzymes that have great promise for the development of new compounds, from new pharmaceuticals to high value commodity and specialty chemicals.
Erin E. Drufva +2 more
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Frontiers in Microbiology, 2021 As the incidence of antibiotic-resistant bacteria has become increased, phage endolysins are believed as one of the promising alternatives to antibiotics.
Bokyung Son +7 more
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Three-Dimensional Domain Swapping Changes the Folding Mechanism of the Forkhead Domain of FoxP1. [PDF]
Biophys J, 2016 The forkhead family of transcription factors (Fox) controls gene transcription during key processes such as regulation of metabolism, embryogenesis, and immunity.
Medina E +6 more
europepmc +2 more sources
Retrotransposon Domain Swapping [PDF]
The Plant Cell, 2010 Whether you consider them major genomic parasites or potentially major drivers of genome expansion, long terminal repeat (LTR) retrotransposons are major, making up 15 to 90% of plant nuclear genomes (reviewed in Sabot and Schulman, 2006). These elements transpose by a replicate-and-paste mechanism, wherein an RNA copy of the retrotransposon is reverse
openaire +2 more sources
Trimeric domain-swapped barnase
Proceedings of the National Academy of Sciences, 1999 The structure of a trimeric domain-swapped form of barnase (EC 3.1.27.3 ) was determined by x-ray crystallography at a resolution of 2.2 Å from crystals of space group R 32.
Zegers, Nathalie +2 more
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Domain-swapping of mesophilic xylanase with hyper-thermophilic glucanase
BMC Biotechnology, 2012 Background Domain fusion is limited at enzyme one terminus. The issue was explored by swapping a mesophilic Aspergillus niger GH11 xylanase (Xyn) with a hyper-thermophilic Thermotoga maritima glucanase (Glu) to construct two chimeras, Xyn-Glu and Glu-Xyn,
Liu Liangwei +5 more
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PLoS Neglected Tropical Diseases, 2022 Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids (Sia) from sialoglycoconjugates to terminal galactose or N-acetylgalactosamine residues of oligosaccharides without the ...
Mario Waespy +6 more
doaj +1 more source
Computational Studies of the Reversible Domain Swapping of p13suc1 [PDF]
Biophysical Journal, 2005 A minimalist representation of protein structures using a Go-like potential for interactions is implemented to investigate the mechanisms of the domain swapping of p13suc1, a protein that exists in two native conformations: a monomer and a domain-swapped dimer formed by the exchange of a beta-strand.
Chahine, J., Cheung, M. S.
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Delayed-Choice Experiments and the Metaphysics of Entanglement [PDF]
, 2012 Delayed-choice experiments in quantum mechanics are often taken to undermine a realistic interpretation of the quantum state. More specifically, Healey has recently argued that the phenomenon of delayed-choice entanglement swapping is incompatible with ...
Egg, Matthias, Matthias Egg
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Molecular Therapy: Methods & Clinical Development, 2022 Recent clinical successes have intensified interest in using adeno-associated virus (AAV) vectors for therapeutic gene delivery. The liver is a key clinical target, given its critical physiological functions and involvement in a wide range of genetic ...
Marti Cabanes-Creus +14 more
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