Domain swapping in allosteric modulation of DNA specificity.
PLoS Biology, 2010 SgrAI is a type IIF restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of cleavage activity and sequence specificity.
Chad K Park +7 more
doaj +3 more sources
A five-residue motif for the design of domain swapping in proteins [PDF]
Nature Communications, 2019 Designing interfaces that can induce protein-protein interactions is a challenging problem. Here the authors show that a five amino acid sequence known to mediate domain swapping in cystatins can drive oligomerization when grafted onto functionally and ...
Neha Nandwani +6 more
doaj +2 more sources
Domain swapping of complementarity-determining region in nanobodies produced by Pichia pastoris [PDF]
AMB Express, 2019 Easy preparation of chimeric nanobodies with various scaffolds is important for customizing abilities of nanobodies toward practical utilization. To accomplish high-throughput production of various nanobodies, utilization of microbes is an attractive ...
Natsuko Miura +7 more
doaj +2 more sources
Domain Swapping in Abiotic Foldamers [PDF]
Angewandte Chemie International EditionAbstractFoldamer sequences that adopt tertiary helix‐turn‐helix folds mediated by helix‐helix hydrogen bonding in organic solvents have been previously reported. In an attempt to create genuine abiotic quaternary structures, i.e. assemblies of tertiary structures, new sequences were prepared that possess additional hydrogen bond donors at positions ...
Shuhe Wang +4 more
openaire +4 more sources
Amino‐acid composition after loop deletion drives domain swapping [PDF]
Protein Science, 2017 Neha Nandwani +2 more
exaly +2 more sources
3D domain swapping: As domains continue to swap [PDF]
Protein Science, 2002 Abstract Three‐dimensional (3D) domain swapping creates a bond between two or more protein molecules as they exchange their identical domains. Since the term '3D domain swapping' was first used to describe the dimeric structure of diphtheria toxin, the database of domain‐swapped proteins has greatly expanded. Analyses of the now about
Yanshun, Liu, David, Eisenberg
openaire +2 more sources
Understanding protein domain-swapping using structure-based models of protein folding [PDF]
Progress in Biophysics and Molecular Biology, 2017 Nahren Manuel Mascarenhas +1 more
exaly +2 more sources
Genome-Wide Prediction and Analysis of 3D-Domain Swapped Proteins in the Human Genome from Sequence Information. [PDF]
PLoS ONE, 2016 3D-domain swapping is one of the mechanisms of protein oligomerization and the proteins exhibiting this phenomenon have many biological functions. These proteins, which undergo domain swapping, have acquired much attention owing to their involvement in ...
Atul Kumar Upadhyay +1 more
doaj +1 more source
Domain Swapping and Retroviral Assembly [PDF]
Molecular Cell, 2005 The structure of a mammalian SCAN domain has been recently reported. The molecule is a structural homolog of the HIV-1 capsid protein and forms a domain-swapped dimer in solution. The authors propose a similar domain-swapping event facilitates HIV-1 assembly, providing a new model for protein-protein interactions underlying viral particle formation.
Kingston, Richard L., Vogt, Volker M.
openaire +2 more sources
Apoprotein Intermolecular Interactions and Heme Insertion for 3D Domain Swapping in Myoglobin [PDF]
ACS OmegaGissi Novientri +7 more
doaj +2 more sources