Energetic Calculations to Decipher pH-Dependent Oligomerization and Domain Swapping of Proteins. [PDF]
PLoS ONE, 2015 Domain swapping mechanism is a specialised mode of oligomerization of proteins in which part of a protein is exchanged in a non-covalent manner between constituent subunits. This mechanism is highly affected by several physiological conditions.
Prashant Shingate +2 more
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Domain Swapping and Retroviral Assembly [PDF]
Molecular Cell, 2005 The structure of a mammalian SCAN domain has been recently reported. The molecule is a structural homolog of the HIV-1 capsid protein and forms a domain-swapped dimer in solution. The authors propose a similar domain-swapping event facilitates HIV-1 assembly, providing a new model for protein-protein interactions underlying viral particle formation.
Kingston, Richard L., Vogt, Volker M.
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REC protein family expansion by the emergence of a new signaling pathway
mBio, 2023 This report presents multi-genome evidence that REC protein family expansion occurs when the emergence of new pathways gives rise to functional discordance.
Megan E. Garber +9 more
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Domain swapping is a consequence of minimal frustration [PDF]
Proceedings of the National Academy of Sciences, 2004 The same energy landscape principles associated with the folding of proteins into their monomeric conformations should also describe how these proteins oligomerize into domain-swapped conformations. We tested this hypothesis by using a simplified model for the epidermal growth factor receptor pathway substrate 8 src homology 3 domain protein, both of ...
Sichun, Yang +6 more
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Dramatic structural changes resulting from the loss of a crucial hydrogen bond in the hinge region involved in C-terminal helix swapping in SurE: a survival protein from Salmonella typhimurium. [PDF]
PLoS ONE, 2013 Domain swapping is an interesting feature of some oligomeric proteins in which each protomer of the oligomer provides an identical surface for exclusive interaction with a segment or domain belonging to another protomer.
Yamuna Kalyani Mathiharan +3 more
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Frontiers in Microbiology, 2021 Cotton is a commercial crop of global importance. The major threat challenging the productivity in cotton has been the lepidopteron insect pest Helicoverpa armigera or cotton bollworm which voraciously feeds on various plant parts.
Kesiraju Karthik +4 more
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IUCrJ, 2020 Protein dimerization or oligomerization resulting from swapping part of the protein between neighboring polypeptide chains is known to play a key role in the regulation of protein function and in the formation of protein aggregates.
Kitaik Lee +12 more
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Structure and stability of recombinant bovine odorant-binding protein: I. Design and analysis of monomeric mutants [PDF]
PeerJ, 2016 Bovine odorant-binding protein (bOBP) differs from other lipocalins by lacking the conserved disulfide bond and for being able to form the domain-swapped dimers.
Olga V. Stepanenko +5 more
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Unraveling the Functional Significance of Unstructured Regions in G Protein-Coupled Receptors
Biomolecules, 2023 Unstructured regions in functional proteins have gained attention in recent years due to advancements in informatics tools and biophysical methods.
Roberto Maggio +5 more
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Statistical disclosure control methods for census frequency tables [PDF]
, 2007 This paper provides a review of common statistical disclosure control (SDC) methods implemented at Statistical Agencies for standard tabular outputs containing whole population counts from a Census (either enumerated or based on a register).
Shlomo, Natalie
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